Zobrazeno 1 - 10
of 288
pro vyhledávání: '"Paul McCormick"'
Autor:
Hugo C. Temperley, Timothy Fannon, Niall J. O’Sullivan, Maeve O’Neill, Benjamin M. Mac Curtain, Charles Gilham, Jacintha O’Sullivan, Grainne O’Kane, Brian J. Mehigan, Sharon O’Toole, John O. Larkin, David Gallagher, Paul McCormick, Michael E. Kelly
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 4005 (2024)
This systematic review investigates the potential of circulating tumour DNA (ctDNA) as a predictive biomarker in the management and prognosis of squamous cell carcinoma of the anal canal (SCCA). PubMed, EMBASE, and Cochrane Central Registry of Contro
Externí odkaz:
https://doaj.org/article/33f2bdf17f874abcb7b231b92804ee81
Autor:
Shaheer I. Khan, Niall J. O’Sullivan, Hugo C. Temperley, Emanuele Rausa, Brian J. Mehigan, Paul McCormick, John O. Larkin, Dara O. Kavanagh, Michael E. Kelly
Publikováno v:
Current Oncology, Vol 30, Iss 1, Pp 416-429 (2022)
Background: Rectal gastrointestinal stromal tumours (GISTs) have many treatment options, but uncertainty remains regarding the best treatment regimen for this rare pathology. The aim of this review is to assess the optimal management approach includi
Externí odkaz:
https://doaj.org/article/4b15f6e245e34a2092bfacbbb19affa8
Autor:
Jim O’Connell, Jayne Doherty, Amy Buckley, David Cormican, Cara Dunne, Karen Hartery, John Larkin, Finbar MacCarthy, Paul McCormick, Susan McKiernan, Brian Mehigan, Cian Muldoon, Ciara Ryan, Jacintha O’Sullivan, David Kevans
Publikováno v:
Intestinal Research, Vol 20, Iss 3, Pp 381-385 (2022)
Externí odkaz:
https://doaj.org/article/48a1ab5320f34b9a949ad5bd28338e5b
Autor:
Michael G. Argenziano, Julia L. Furnari, Michael L. Miller, Yu Sun, Matei A. Banu, Justin A. Neira, Matija Snuderl, Jeffrey N. Bruce, Mary Welch, Paul McCormick, Peter Canoll
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-7 (2022)
Abstract We present the case of a 41-year-old man who developed worsening mid-thoracic back pain and imaging revealed a well-circumscribed intramedullary tumor in the thoracic spinal cord. Subtotal resection was performed, and histopathological analy
Externí odkaz:
https://doaj.org/article/0c25799048174155b51d0a19071a0280
Autor:
Susan A. Kennedy, Maria E. Morrissey, Margaret R. Dunne, Fiona O’Connell, Clare T. Butler, Mary-Clare Cathcart, Amy M. Buckley, Brian J. Mehigan, John O. Larkin, Paul McCormick, Breandán N. Kennedy, Jacintha O’Sullivan
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-14 (2020)
Abstract Background Colorectal cancer (CRC) is the second most common cause of cancer-related mortality worldwide with one in every five patients diagnosed with metastatic CRC (mCRC). In mCRC cases, the 5-year survival rate remains at approximately 1
Externí odkaz:
https://doaj.org/article/8a55b1ac41ea46598fac7e188fb44562
Autor:
Maria E. Morrissey, Róisín Byrne, Celina Nulty, Niamh H. McCabe, Niamh Lynam-Lennon, Clare T. Butler, Susan Kennedy, Dermot O’Toole, John Larkin, Paul McCormick, Brian Mehigan, Mary-Clare Cathcart, Joanne Lysaght, John V. Reynolds, Elizabeth J. Ryan, Margaret R. Dunne, Jacintha O’Sullivan
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background Only 10–30% of oesophageal and rectal adenocarcinoma patients treated with neoadjuvant chemoradiotherapy have a complete pathological response. Inflammatory and angiogenic mediators in the tumour microenvironment (TME) may enabl
Externí odkaz:
https://doaj.org/article/eac61d4bd7544b4db891309c642d064c
Autor:
Aisling B. Heeran, Helen P. Berrigan, Croí E. Buckley, Heleena Moni Bottu, Orla Prendiville, Amy M. Buckley, Niamh Clarke, Noel E. Donlon, Timothy S. Nugent, Michael Durand, Cara Dunne, John O. Larkin, Brian Mehigan, Paul McCormick, Lorraine Brennan, Niamh Lynam-Lennon, Jacintha O'Sullivan
Publikováno v:
Translational Oncology, Vol 14, Iss 1, Pp 100882- (2021)
Locally advanced rectal cancer is treated with neoadjuvant-chemoradiotherapy, however only 22% of patients achieve a complete response. Resistance mechanisms are poorly understood. Radiation-induced Bystander Effect (RIBE) describes the effect of rad
Externí odkaz:
https://doaj.org/article/24e333a5a2ae47b7a8972b8cd7d23308
Autor:
Aisling B. Heeran, Margaret R. Dunne, Maria E. Morrissey, Croí E. Buckley, Niamh Clarke, Aoife Cannon, Noel E. Donlon, Timothy S. Nugent, Michael Durand, Cara Dunne, John O. Larkin, Brian Mehigan, Paul McCormick, Niamh Lynam-Lennon, Jacintha O’Sullivan
Publikováno v:
Cancers, Vol 13, Iss 3, p 571 (2021)
Locally advanced rectal cancer is treated with neoadjuvant-chemoradiotherapy; however, only ~22% of patients achieve a complete response, and resistance mechanisms are poorly understood. The role of inflammation and immune cell biology in this settin
Externí odkaz:
https://doaj.org/article/4b8485e6768e449cba1bb16ecaad7db8
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 8 (2016)
Treatment strategies for metastatic colorectal cancer (mCRC) patients have undergone dramatic changes in the past decade and despite improved patient outcomes, there still exist areas for continued development. The introduction of targeted agents has
Externí odkaz:
https://doaj.org/article/24bc57e410de408aa9c6921e8ebdb90d
Autor:
Hasan Al Chalabi, James M. O’Riordan, Alex Richardson, Delia Flannery, Katrina O'Connor, Charlotte Stuart, John Larkin, Paul McCormick, Brian Mehigan
Publikováno v:
Surgery Research and Practice, Vol 2014 (2014)
Aims and Objectives. To review the experience of a nurse-led colorectal cancer follow-up clinic in a tertiary referral colorectal cancer centre. Methodology. Data from the nurse-led colorectal cancer follow-up clinic in our unit was prospectively mai
Externí odkaz:
https://doaj.org/article/a3aad22af39c4aad9f3792fa97110eb6