Modeling Alzheimer's disease progression utilizing clinical trial and ADNI data to predict longitudinal trajectory of CDR‐SB

Autor: Samira Jamalian, Michael Dolton, Pascal Chanu, Vidya Ramakrishnan, Yesenia Franco, Kristin Wildsmith, Paul Manser, Edmond Teng, Jin Y. Jin, Angelica Quartino, Joy C. Hsu, for the Alzheimer's Disease Neuroimaging Initiative

Publikováno v: CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 7, Pp 1029-1042 (2023)

Abstract There is strong interest in developing predictive models to better understand individual heterogeneity and disease progression in Alzheimer's disease (AD). We have built upon previous longitudinal AD progression models, using a nonlinear, mi

Externí odkaz: https://doaj.org/article/3b249fe4407842a7bf2bc7d8b35b90cc

The Alzheimer's Disease Prediction Of Longitudinal Evolution (TADPOLE) Challenge: Results after 1 Year Follow-up

Autor: Marinescu, Razvan V., Oxtoby, Neil P., Young, Alexandra L., Bron, Esther E., Toga, Arthur W., Weiner, Michael W., Frederik Barkhof, Fox, Nick C., Arman Eshaghi, Tina Toni, Marcin Salaterski, Veronika Lunina, Manon Ansart, Stanley Durrleman, Pascal Lu, Samuel Iddi, Dan Li, Thompson, Wesley K., Donohue, Michael C., Aviv Nahon, Yarden Levy, Dan Halbersberg, Mariya Cohen, Huiling Liao, Tengfei Li, Kaixian Yu, Hongtu Zhu, Tamez-Peña, José G., Aya Ismail, Timothy Wood, Hector Corrada Bravo, Minh Nguyen, Nanbo Sun, Jiashi Feng, Thomas Yeo, B. T., Gang Chen, Ke Qi, Shiyang Chen, Deqiang Qiu, Ionut Buciuman, Alex Kelner, Raluca Pop, Denisa Rimocea, Ghazi, Mostafa M., Mads Nielsen, Sebastien Ourselin, Lauge Sørensen, Vikram Venkatraghavan, Keli Liu, Christina Rabe, Paul Manser, Hill, Steven M., James Howlett, Zhiyue Huang, Steven Kiddle, Sach Mukherjee, Anaïs Rouanet, Bernd Taschler, Tom, Brian D. M., White, Simon R., Noel Faux, Suman Sedai, Javier de Velasco Oriol, Clemente, Edgar E. V., Karol Estrada, Leon Aksman, Andre Altmann, Stonnington, Cynthia M., Yalin Wang, Jianfeng Wu, Vivek Devadas, Clementine Fourrier, Lars Lau Raket, Aristeidis Sotiras, Guray Erus, Jimit Doshi, Christos Davatzikos, Jacob Vogel, Andrew Doyle, Angela Tam, Alex Diaz-Papkovich, Emmanuel Jammeh, Igor Koval, Paul Moore, Lyons, Terry J., John Gallacher, Jussi Tohka, Robert Ciszek, Bruno Jedynak, Kruti Pandya, Murat Bilgel, William Engels, Joseph Cole, Polina Golland, Stefan Klein, Alexander, Daniel C.

Publikováno v: Machine Learning for Biomedical Imaging, 1
EUR Research Portal

We present the findings of "The Alzheimer's Disease Prediction Of Longitudinal Evolution" (TADPOLE) Challenge, which compared the performance of 92 algorithms from 33 international teams at predicting the future trajectory of 219 individuals at risk

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab0e7be456a19285c3315e5245732697
https://pure.eur.nl/en/publications/d50d3c2a-cf7b-42d1-84b4-d4faacfe53e6

A Trial of D-Cycloserine to Treat Stereotypies in Older Adolescents and Young Adults With Autism Spectrum Disorder

Autor: Leonore Okwara, Kathrin Hartmann, Paul Manser, Stephen I. Deutsch, Amy L. Herndon, Maria R. Urbano

OBJECTIVES Autism spectrum disorders (ASDs) have core impairments in social communication as well as the presence of repetitive, stereotypic behaviors and restricted interests. Older adolescents and young adults are particularly impacted by these def

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7090f7ccea378bca4eac3364db7c7615
https://europepmc.org/articles/PMC4354861/

Quality control and monitoring schemes

Autor: Paul Manser

Publikováno v: In Practice. 16:197-203

Providing a quality service demands checks, controls and established procedures. To assure customers and management that these are being done requires records, documents and audits, leading inevitably (and unfortunately) to increased administration a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2f10f49853114932f3cb386f75a6904d
https://doi.org/10.1136/inpract.16.4.197