Zobrazeno 1 - 10
of 285
pro vyhledávání: '"Paul M. Pilowsky"'
Autor:
Sheran Li, Cara M. Hildreth, Ahmed A. Rahman, Sean A. Barton, Benjamin F. Wyse, Chai K. Lim, Paul M. Pilowsky, Jacqueline K. Phillips
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract We examined the effect of total and afferent renal denervation (RDN) on hypertension and the renin-angiotensin system (RAS) in a rodent model of juvenile-onset polycystic kidney disease (PKD). Lewis Polycystic Kidney (LPK) and control rats r
Externí odkaz:
https://doaj.org/article/48a77c43345347dcab9d38e3bb3a6bbb
Autor:
Melissa M. J. Farnham, Vikram J. Tallapragada, Edward T. O’Connor, Polina E. Nedoboy, Bowen Dempsey, Suja Mohammed, Angelina Y. Fong, Mandy S. Y. Lung, Fatemeh Derakhshan, Richard J. A. Wilson, Paul M. Pilowsky
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Repetitive hypoxia is a key feature of obstructive sleep apnoea (OSA), a condition characterized by intermittent airways obstruction. Patients with OSA present with persistent increases in sympathetic activity and commonly develop hypertension. The o
Externí odkaz:
https://doaj.org/article/0ef07b32c2494c1693cc4943dcb54255
Autor:
Paul M. Pilowsky
Publikováno v:
Angiotensin ISBN: 9780323996181
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef30857e6b96db5745b106a21ec8db56
https://doi.org/10.1016/b978-0-323-99618-1.05001-7
https://doi.org/10.1016/b978-0-323-99618-1.05001-7
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 473:107-120
Oxaliplatin is a platinum-based alkylating chemotherapeutic agent used for cancer treatment. Neurotoxicity is one of its major adverse effects that often demands dose limitation. However, the effects of chronic oxaliplatin on the toxicity of the auto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::164bc44f64c4c1a94a20a96379cdc39f
https://doi.org/10.1007/s00424-020-02480-4
https://doi.org/10.1007/s00424-020-02480-4
Autor:
Chai K. Lim, Ahmed A. Rahman, Jacqueline K. Phillips, Cara M. Hildreth, Paul M. Pilowsky, Sean A. Barton, Sheran Li, Benjamin F. Wyse
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
We examined the effect of total and afferent renal denervation (RDN) on hypertension and the renin-angiotensin system (RAS) in a rodent model of juvenile-onset polycystic kidney disease (PKD). Lewis Polycystic Kidney (LPK) and control rats received t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7ee85ea09f6bc5bc32fe92f35a777ec
http://europepmc.org/articles/PMC8275789
http://europepmc.org/articles/PMC8275789
Autor:
Polina E. Nedoboy, Paul M. Pilowsky, E. Myfanwy Cohen, Mary M. Kavurma, Zohra M. Kakall, Peter R. C. Howe
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism
The impaired ability of the autonomic nervous system to respond to hypoglycemia is termed “hypoglycemia-associated autonomic failure” (HAAF). This life-threatening phenomenon results from at least two recent episodes of hypoglycemia, but the path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dec1e4ebfb8383105b8be80cfe4bf59a
https://doi.org/10.1152/ajpendo.00051.2019
https://doi.org/10.1152/ajpendo.00051.2019
Autor:
Melissa M.J. Farnham, Seung Jae Kim, E. Myfanwy Cohen, Zohra M. Kakall, Paul M. Pilowsky, Polina E. Nedoboy
Publikováno v:
Respiratory Physiology & Neurobiology. 265:83-91
Autonomic reflex responses are critical in restoring changes to circulatory factors reduced beyond the domain of homeostasis. Intermittent hypoxia triggers repeated activation of chemoreflexes, resulting in baroreflex dysfunction and widespread chang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6333f37beefc75b02fdc2d4be4c7638e
https://doi.org/10.1016/j.resp.2018.08.008
https://doi.org/10.1016/j.resp.2018.08.008
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 315:R1115-R1122
Activation of neurons in the rostral ventrolateral medulla (RVLM) following glucoprivation initiates sympathoadrenal activation, adrenaline release, and increased glucose production. Here, we aimed to determine the role of RVLM µ-opioid receptors in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c65079ec432f471ec65a38ea11663200
https://doi.org/10.1152/ajpregu.00248.2018
https://doi.org/10.1152/ajpregu.00248.2018
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::def4bd9389cf0a056f6c8f766b17b80d
https://doi.org/10.1096/fasebj.2021.35.s1.05286
https://doi.org/10.1096/fasebj.2021.35.s1.05286
Autor:
Paul M. Pilowsky
Angiotensin: From the Kidney to Coronavirus, a new volume in the Molecular Mediators in Health and Disease series, presents the communication role of the hormone in both health and disease states. Beyond the most common conditions, the book also expl