Zobrazeno 1 - 10
of 668
pro vyhledávání: '"Paul M. O‘Byrne"'
Autor:
Maral Ranjbar, Ruth P. Cusack, Christiane E. Whetstone, Danica L. Brister, Jennifer Wattie, Lesley Wiltshire, Nadia Alsaji, Jennifer Le Roux, Eric Cheng, Thivya Srinathan, Terence Ho, Roma Sehmi, Paul M. O’Byrne, Maryonne Snow-Smith, Michelle Makiya, Amy D. Klion, MyLinh Duong, Gail M. Gauvreau
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6427 (2024)
Background: The immune response dynamics in COVID-19 patients remain a subject of intense investigation due to their implications for disease severity and treatment outcomes. We examined changes in leukocyte levels, eosinophil activity, and cytokine
Externí odkaz:
https://doaj.org/article/fda2923a573a441882051699bd42c621
Autor:
Mohsen Sadatsafavi, J. Mark FitzGerald, Paul M. O’Byrne, Mena Soliman, Niroshan Sriskandarajah, Colin Vicente, Sarowar Muhammad Golam
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 17, Iss 1, Pp 1-13 (2021)
Abstract Background The Global Initiative for Asthma recommends the use of as-needed low-dose inhaled corticosteroid (ICS)-formoterol as a preferred controller therapy for patients with mild asthma. These recommendations were based, in part, on evide
Externí odkaz:
https://doaj.org/article/c4b094a1c11345eda39bfce98150ac78
Autor:
Imran Satia, Alexandra J. Mayhew, Nazmul Sohel, Om Kurmi, Kieran J. Killian, Paul M. O'Byrne, Parminder Raina
Publikováno v:
ERJ Open Research, Vol 8, Iss 2 (2022)
Background Chronic cough is a common troublesome condition, but risk factors for developing chronic cough are poorly understood. The aim of this study was to understand the relationship between mental health disorders, personality traits and chronic
Externí odkaz:
https://doaj.org/article/8bd9c40ac13d488db76dc6cf4c449499
Autor:
Eldar Priel, Mustafaa Wahab, Tapas Mondal, Andy Freitag, Paul M. O'Byrne, Kieran J. Killian, Imran Satia
Publikováno v:
Current Research in Physiology, Vol 4, Iss , Pp 235-242 (2021)
Background: Beta blockers prolong life in patients with cardiovascular diseases. Negative chronotropic and inotropic effects carry the potential to adversely effect peripheral skeletal and airway smooth muscle contributing to further fatigue, dyspnea
Externí odkaz:
https://doaj.org/article/8335be39924b438ea61044892a60f9ca
Autor:
Chen Zhan, Rong Xu, Bizhou Li, Jiaxing Liu, Wanqin Liang, Shengfang Zhang, Liman Fang, Shuxin Zhong, S. Dushinka Shaniya Helen de Silva, Dhinesan Sivapalan, Wei Luo, Jing Li, Kefang Lai, Nanshan Zhong, Roma Sehmi, Paul M. O’Byrne, Ruchong Chen
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
ObjectiveThis study aims to explore the potential of in situ airway differentiation of eosinophil progenitors (EoPs) and hematopoietic progenitor cells (HPCs) in sputum and peripheral blood from patients with non-asthmatic eosinophilic bronchitis (NA
Externí odkaz:
https://doaj.org/article/f426ac6d95754e7ca084270c398cabf1
Autor:
Elena Kum, Gordon H. Guyatt, Caroline Munoz, Suzanne Beaudin, Shelly-Anne Li, Rayid Abdulqawi, Huda Badri, Louis-Philippe Boulet, Ruchong Chen, Peter Dicpinigaitis, Lieven Dupont, Stephen K. Field, Cynthia L. French, Peter G. Gibson, Richard S. Irwin, Paul Marsden, Lorcan McGarvey, Jaclyn A. Smith, Woo-Jung Song, Paul M. O'Byrne, Imran Satia
Publikováno v:
ERJ Open Research, Vol 8, Iss 1 (2022)
Background Cough symptom severity represents an important subjective end-point to assess the impact of therapies for patients with refractory or unexplained chronic cough (RCC/UCC). As existing instruments assessing the severity of cough are neither
Externí odkaz:
https://doaj.org/article/151080ea31be480ea6c85ee1880825c7
Autor:
Mangalakumari Jeyanathan, Dominik K. Fritz, Sam Afkhami, Emilio Aguirre, Karen J. Howie, Anna Zganiacz, Anna Dvorkin-Gheva, Michael R. Thompson, Richard F. Silver, Ruth P. Cusack, Brian D. Lichty, Paul M. O’Byrne, Martin Kolb, Maria Fe C. Medina, Myrna B. Dolovich, Imran Satia, Gail M. Gauvreau, Zhou Xing, Fiona Smaill
Publikováno v:
JCI Insight, Vol 7, Iss 3 (2022)
Background Adenovirus-vectored (Ad-vectored) vaccines are typically administered via i.m. injection to humans and are incapable of inducing respiratory mucosal immunity. However, aerosol delivery of Ad-vectored vaccines remains poorly characterized,
Externí odkaz:
https://doaj.org/article/0f5b7f6ff7fa419a8108b00742172faf
Autor:
Imran Satia, Alexandra J. Mayhew, Nazmul Sohel, Om Kurmi, Kieran J. Killian, Megan E. O'Connell, Paul M. O'Byrne, Parminder Raina
Publikováno v:
ERJ Open Research, Vol 8, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/9eb0e36e63774b0f93ab56c4d598b2c7
Autor:
Donald W. Cockcroft, Beth E. Davis, Christianne M. Blais, Louis-Philippe Boulet, Marie-Éve Boulay, Hélène Villeneuve, Gail M. Gauvreau, Paul M. O’Byrne, Karen J. Howie, Caitlin D. Obminski
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 15, Iss 1, Pp 1-8 (2019)
Abstract Background Allergen inhalation tests are a valuable research tool. The allergen dose producing an early asthmatic response (EAR) can be predicted from methacholine responsiveness and allergen skin test endpoint (STE). The Wright® jet nebuli
Externí odkaz:
https://doaj.org/article/099c329570ba4e55847fc02251f979e7
Autor:
Elena Kum, Gordon H. Guyatt, Tahira Devji, Yuting Wang, Layla Bakaa, Lucy Lan, Eva Liu, Alexander Mastrolonardo, Rachel Couban, Paul M. O'Byrne, Imran Satia
Publikováno v:
European Respiratory Review, Vol 30, Iss 161 (2021)
Background Cough severity represents an important subjective endpoint in assessing the effectiveness of therapies for patients with chronic cough. Although cough-specific quality of life questionnaires exist, a widely available cough severity instrum
Externí odkaz:
https://doaj.org/article/39f77f706fe045dbaea918e22ad23248