Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Paul M. McGregor"'
Autor:
Laurel A. Keefer, James R. White, Derrick E. Wood, Kelly M. R. Gerding, Kenneth C. Valkenburg, David Riley, Christopher Gault, Eniko Papp, Christine M. Vollmer, Amy Greer, James Hernandez, Paul M. McGregor, Adriana Zingone, Bríd M. Ryan, Kristen Deak, Shannon J. McCall, Michael B. Datto, James L. Prescott, John F. Thompson, Gustavo C. Cerqueira, Siân Jones, John K. Simmons, Abigail McElhinny, Jennifer Dickey, Samuel V. Angiuoli, Luis A. Diaz, Victor E. Velculescu, Mark Sausen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The genomic profiling of tumours has not been widely adopted in the clinic due to technical and practical hurdles. Here, the authors develop PGDx elio tissue complete, a scalable, standardised and FDA-cleared test comprising a targeted gene panel and
Externí odkaz:
https://doaj.org/article/e4aa27119f0a4f1f9ac75c8283f59ea8
Autor:
Lun-Ching Chang, Biswajit Das, Chih-Jian Lih, Han Si, Corinne E. Camalier, Paul M. McGregor III, Eric Polley
Publikováno v:
Cancer Informatics, Vol 2016, Iss 15, Pp 65-71 (2016)
Externí odkaz:
https://doaj.org/article/5aaa7801d8154746a41329b20ecc70e5
Autor:
Ellen L. Verner, Jennifer B. Jackson, Eric Severson, Kenneth C. Valkenburg, Amy E. Greer, David R. Riley, Mark Sausen, Cynthia Maddox, Paul M. McGregor, Aanavi Karandikar, Stephanie B. Hastings, Rebecca A. Previs, Venkataprasanth P. Reddy, Taylor J. Jensen, Shakti H. Ramkissoon
Publikováno v:
The Journal of Molecular Diagnostics.
Autor:
James H. Doroshow, Richard M. Simon, Barbara A. Conley, Robert J. Kinders, P. Mickey Williams, Seth M. Steinberg, Paul M. McGregor, William D. Walsh, Michele G. Mehaffey, Chih-Jian Lih, Deborah E. Allen, Jiuping Ji, Alice P. Chen, Ahrim Youn, Peter M. Szabo, Robert J. Morgan, Miguel A. Villalona-Calero, Michael J. Naughton, David R. Gandara, Daniel M. Sullivan, Gini F. Fleming, Amit M. Oza, Shivaani Kummar
Supplemental Figure S1. Kaplan-Meier analysis of the progression free survival (PFS) of patients on each treatment arm stratified by BRCA status showed no significant differences.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac78b660c4e98ad73ca9863a9f1c1ebb
https://doi.org/10.1158/1078-0432.22461263.v1
https://doi.org/10.1158/1078-0432.22461263.v1
Autor:
James H. Doroshow, Richard M. Simon, Barbara A. Conley, Robert J. Kinders, P. Mickey Williams, Seth M. Steinberg, Paul M. McGregor, William D. Walsh, Michele G. Mehaffey, Chih-Jian Lih, Deborah E. Allen, Jiuping Ji, Alice P. Chen, Ahrim Youn, Peter M. Szabo, Robert J. Morgan, Miguel A. Villalona-Calero, Michael J. Naughton, David R. Gandara, Daniel M. Sullivan, Gini F. Fleming, Amit M. Oza, Shivaani Kummar
Supplementary Expression Data. Individual expression values for all 211 genes interrogated in the tumor tissue of 55 patients.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4719fdaa52cff5b2368e357113fb40cf
https://doi.org/10.1158/1078-0432.22461254
https://doi.org/10.1158/1078-0432.22461254
Autor:
James H. Doroshow, Richard M. Simon, Barbara A. Conley, Robert J. Kinders, P. Mickey Williams, Seth M. Steinberg, Paul M. McGregor, William D. Walsh, Michele G. Mehaffey, Chih-Jian Lih, Deborah E. Allen, Jiuping Ji, Alice P. Chen, Ahrim Youn, Peter M. Szabo, Robert J. Morgan, Miguel A. Villalona-Calero, Michael J. Naughton, David R. Gandara, Daniel M. Sullivan, Gini F. Fleming, Amit M. Oza, Shivaani Kummar
Purpose: Veliparib, a PARP inhibitor, demonstrated clinical activity in combination with oral cyclophosphamide in patients with BRCA-mutant solid tumors in a phase I trial. To define the relative contribution of PARP inhibition to the observed clinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a59e143b68831612282f14d975a5acd
https://doi.org/10.1158/1078-0432.c.6524744.v1
https://doi.org/10.1158/1078-0432.c.6524744.v1
Autor:
James H. Doroshow, Richard M. Simon, Barbara A. Conley, Robert J. Kinders, P. Mickey Williams, Seth M. Steinberg, Paul M. McGregor, William D. Walsh, Michele G. Mehaffey, Chih-Jian Lih, Deborah E. Allen, Jiuping Ji, Alice P. Chen, Ahrim Youn, Peter M. Szabo, Robert J. Morgan, Miguel A. Villalona-Calero, Michael J. Naughton, David R. Gandara, Daniel M. Sullivan, Gini F. Fleming, Amit M. Oza, Shivaani Kummar
Supplementary Methods, Tables S1 and S2, Figure Legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::328021638afbe02d32a6d9991afde791
https://doi.org/10.1158/1078-0432.22461251
https://doi.org/10.1158/1078-0432.22461251
Autor:
Laurel A. Keefer, James R. White, Derrick E. Wood, Kelly M. R. Gerding, Kenneth C. Valkenburg, David Riley, Christopher Gault, Eniko Papp, Christine M. Vollmer, Amy Greer, James Hernandez, Paul M. McGregor, Adriana Zingone, Bríd M. Ryan, Kristen Deak, Shannon J. McCall, Michael B. Datto, James L. Prescott, John F. Thompson, Gustavo C. Cerqueira, Siân Jones, John K. Simmons, Abigail McElhinny, Jennifer Dickey, Samuel V. Angiuoli, Luis A. Diaz, Victor E. Velculescu, Mark Sausen
Publikováno v:
Nature communications. 13(1)
The lack of validated, distributed comprehensive genomic profiling assays for patients with cancer inhibits access to precision oncology treatment. To address this, we describe elio tissue complete, which has been FDA-cleared for examination of 505 c
Autor:
Chih Jian Lih, Michele G. Mehaffey, Lisa A. Boardman, James V. Tricoli, Paul M. McGregor, Wayne L. Furman, Armita Bahrami, Barbara A. Conley, P. Mickey Williams, Jin S. Jang, William D. Walsh, Sivasish Sindiri, Javed Khan, Rajesh Patidar, Corinne Camalier
Publikováno v:
Cancer. 124:1070-1082
Background It is possible that the relative lack of progress in treatment outcome among the adolescent and young adult (AYA) group of cancer patients is due to a difference in disease biology compared to the corresponding diseases in younger and olde
Autor:
David J. Sims, Corinne Camalier, P. Mickey Williams, Kneshay N. Harper, Barbara A. Conley, James H. Doroshow, Paul M. McGregor, Biswajit Das, Courtney H. Bouk, Robin D. Harrington, Thomas Forbes, Chih Jian Lih, Eric C. Polley, Michele G. Mehaffey
Although next-generation sequencing technologies have been widely adapted for clinical diagnostic applications, an urgent need exists for multianalyte calibrator materials and controls to evaluate the performance of these assays. Control materials wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0e8fc30838f960e73cd330347249022
https://europepmc.org/articles/PMC4851732/
https://europepmc.org/articles/PMC4851732/