Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Paul M. Kunko"'
Publikováno v:
Behavioural Brain Research. 99:201-208
Chronic continuous cocaine treatment produces a unique pattern of locomotor activation over time. An initial, progressive increase in locomotion is indicative of sensitization. Unlike intermittent cocaine, this increase is subsequently reversed durin
Publikováno v:
Synapse. 30:275-283
U-69593, the selective K-opioid agonist, was repeatedly administered in single daily injections (0.32 mg/kg) to male, Sprague-Dawley rats. Two or ten days later, the rats were euthanized and dopamine D1 and D2 receptors were measured using (3H]SCH 23
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 356:562-569
The chronic continuous infusion of cocaine produces partial behavioral tolerance to cocaine and tolerance to the inhibition of dopamine uptake by cocaine, without changing dopamine transporter binding. In order to examine more closely the dopaminergi
Publikováno v:
Pharmacology Biochemistry and Behavior. 55:559-564
The developmental and behavioral effects of prenatal exposure to cocaine and/or ethanol were examined in rats. Pregnant rats received ethanol (E; 2 g/kg b.i.d.) orally, cocaine (C; 6 mg/kg/day, IV), or both ( C E ) on gestational days 8–20. Control
Publikováno v:
Developmental Brain Research. 95:118-121
On postnatal day 4, rats exposed to methadone prenatally but fostered to control dams, as well as those fostered to dams treated with methadone, exhibited significant reductions in striatal acetylcholine (ACh) content. This suggests that neonatal wit
Publikováno v:
Pharmacology Biochemistry and Behavior. 50:627-633
The effects of cocaine and the cocaine analog methyl-3-beta-(p-fluorophenyl)-1 alpha H, 5 alpha H-tropane-2b-carboxylate (CFT) on glutamate turnover rate were studied in the nucleus accumbens, striatum, frontal cortex, and parietal-cingulate cortex o
Publikováno v:
Pharmacology Biochemistry and Behavior. 48:161-168
Amphetamine (which enhances dopaminergic, cholinergic, and glutamatergic activity) increases release of ascorbic acid (AA) and uric acid (UA) in the caudate nucleus. In this study, linear sweep voltammetry with carbon past electrodes was used to inve
Publikováno v:
Neurotoxicology and Teratology. 15:335-344
Pregnant rats were injected with cocaine (CN; 6 mg/kg) or an equal volume of saline (SAL), via the tail vein, on gestation days 8-20. A third group was untreated (UT). Maternal weight gain was not affected by dam treatment despite slight differences
Autor:
Kathyrne Mueller, Paul M. Kunko
Publikováno v:
Pharmacology Biochemistry and Behavior. 35:871-876
Linear sweep voltammetry was used to investigate the effects of amphetamine (which enhances the release of dopamine) and/or pilocarpine (a cholinergic agonist) on the release of ascorbic acid and uric acid in brain areas differing in dopamine and ace
Autor:
Sari Izenwasser, Bruce Ladenheim, F. Ivy Carroll, Paul M. Kunko, Jean Lud Cadet, Stephanie L. Collins
Publikováno v:
Synapse (New York, N.Y.). 45(3)
Continuous infusion of cocaine or the selective dopamine uptake inhibitors GBR 12909 or RTI-117 increases locomotor stimulation, to which partial tolerance occurs. In addition, all three drugs produce significant decreases in tyrosine hydroxylase imm