Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Paul M. Howley"'
Publikováno v:
Expert Review of Vaccines, Vol 17, Iss 10, Pp 925-934 (2018)
Introduction: With the increasing number of vaccines and vaccine-preventable diseases, the pressure to generate multi-valent and multi-pathogen vaccines grows. Combining individual established vaccines to generate single-shot formulations represents
Externí odkaz:
https://doaj.org/article/2dbf7c5aaf93487fa930b4b90a8ff06c
Autor:
Natalie A. Prow, Liang Liu, Eri Nakayama, Tamara H. Cooper, Kexin Yan, Preethi Eldi, Jessamine E. Hazlewood, Bing Tang, Thuy T. Le, Yin Xiang Setoh, Alexander A Khromykh, Jody Hobson-Peters, Kerrilyn R. Diener, Paul M. Howley, John D. Hayball, Andreas Suhrbier
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Zika and chikungunya virus are co-circulating in many regions and currently there is no approved vaccine for either virus. Here, the authors engineer one vaccinia virus based vaccine for both, Zika and chikungunya, and show protection from infection
Externí odkaz:
https://doaj.org/article/fb33c22d0fd945c1b4999adae6928f2c
Autor:
Liang Liu, Tamara Cooper, Preethi Eldi, Pablo Garcia-Valtanen, Kerrilyn R. Diener, Paul M. Howley, John D. Hayball
Publikováno v:
BioTechniques, Vol 62, Iss 4, Pp 183-187 (2017)
Recombinant vaccinia viruses (rVACVs) are promising antigen-delivery systems for vaccine development that are also useful as research tools. Two common methods for selection during construction of rVACV clones are (i) co-insertion of drug resistance
Externí odkaz:
https://doaj.org/article/b3404c6f21114b35a0e331a2f981ba5f
Autor:
Wilson Nguyen, Eri Nakayama, Kexin Yan, Bing Tang, Thuy T. Le, Liang Liu, Tamara H. Cooper, John D. Hayball, Helen M. Faddy, David Warrilow, Richard J. N. Allcock, Jody Hobson-Peters, Roy A. Hall, Daniel J. Rawle, Viviana P. Lutzky, Paul Young, Nidia M. Oliveira, Gunter Hartel, Paul M. Howley, Natalie A. Prow, Andreas Suhrbier
Publikováno v:
Vaccines, Vol 8, Iss 2, p 209 (2020)
Chikungunya virus (CHIKV), Ross River virus (RRV), o’nyong nyong virus (ONNV), Mayaro virus (MAYV) and Getah virus (GETV) represent arthritogenic alphaviruses belonging to the Semliki Forest virus antigenic complex. Antibodies raised against one of
Externí odkaz:
https://doaj.org/article/ab91253b909a4655ac9a7f198f2a6b40
Publikováno v:
Viruses, Vol 6, Iss 10, Pp 3787-3808 (2014)
Vaccinia virus (VACV) has achieved unprecedented success as a live viral vaccine for smallpox which mitigated eradication of the disease. Vaccinia virus has a complex virion morphology and recent advances have been made to answer some of the key outs
Externí odkaz:
https://doaj.org/article/8016ecaabbe34456a2955a6e7733d0b5
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1139
Fowlpox virus (FPV) is a double-stranded DNA virus with a history of use as a live attenuated vaccine in commercial poultry production systems. FPV is also highly amenable to genetic engineering, with a large cloning capacity and many nonessential si
Autor:
Danièle Spehner, Paul M. Howley, Bernard A. P. Lafont, Robert Drillien, Martin A. Billeter, Karin Kaelin
Publikováno v:
Journal of Virological Methods. 79:65-74
Measles virus encodes three proteins required for the encapsidation, transcription and replication of viral genomes. The genes for these proteins have been inserted into the vaccinia virus genome together with the gene for the bacteriophage T7 RNA po
Publikováno v:
Virology. 232(2):260-268
Measles virus nucleoprotein encoded from the vaccinia virus genome assembles into nucleocapsids similar in many respects to those observed during a natural measles virus infection. The influence of the measles virus phosphoprotein on nucleocapsid ass
Autor:
John A. Gatehouse, Paul M. Howley
Publikováno v:
Plant Molecular Biology. 33:175-180
This paper describes a target sequence for a pea seed nuclear DNA-binding protein (of Pisum sativum) present at the cell expansion phase. Electromobility shift assays as well as in situ copper-phenanthroline footprinting have shown that this protein
Publikováno v:
Gene. 172(2)
A vaccinia virus (VV) transfer vector is described which enables integration of heterologous sequences into the I4L locus (ribonucleotide reductase-encoding gene) through co-insertion of a GUS selection marker. I4L- VV recombinants formed blue plaque