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of 152
pro vyhledávání: '"Paul M. Gross"'
Publikováno v:
Pharmacology Biochemistry and Behavior. 51:37-47
Injection of the neuropeptide, endothelin-1 (ET, range of 3–9 pmol), into a lateral ventricle (ICV) of rats produced barrel rolling and other convulsions including ataxia, forelimb and facial clonus, nystagmus, and tonic extension of the tail and h
Publikováno v:
Neuropharmacology. 33:915-927
A solution containing S-nitroso-N-acetylpenicillamine (SNAP), a nitric oxide (NO.-releasing compound, was microinjected in doses of 0.25-2 mumol into a lateral ventricle of conscious rats. SNAP produced dose-dependent convulsions similar to those ass
Autor:
Alan Kim Johnson, Paul M. Gross
Publikováno v:
The FASEB Journal. 7:678-686
Circumventricular organs (CVOs), small structures bordering the ventricular spaces in the midline of the brain, have common morphological and endocrine-like characteristics that distinguish them from the rest of the nervous system. Among their unique
Publikováno v:
Brain Research. 606:135-142
We examined the hypothesis that the vascular- and brain-derived peptide, endothelin-1 (ET), would affect cerebral neuroendocrine structures when administered via the peripheral circulation or via a lateral cerebral ventricle (i.c.v.). ET was infused
Publikováno v:
Biochemical and Biophysical Research Communications. 190:975-981
Endothelin-1 (ET) and sodium nitroprusside (SNP, which liberates nitric oxide, NO) were given alone or together into a lateral cerebral ventricle (icv) of anesthetized rats to assess their potential interaction on cerebral rates of glucose metabolism
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 263:H1806-H1810
Endothelin (ET) is a potent vasoconstrictor peptide that may have pathophysiological roles in the microcirculation of the peripheral nervous system. We examined the local action of epineurial ET-1 on sciatic endoneurial blood flow using serial hydrog
Publikováno v:
Brain Research. 579:99-106
Blood-brain transfer constants for a small, neutral amino acid tracer, [14C]alpha-aminoisobutyric acid (AIB), were measured by quantitative autoradiography and image analysis in 15 individual brain structures of 2-kidney, 1-clip renal hypertensive ra
Cerebral hypermetabolism produced by intraventricular endothelin-1 in rats: Inhibition by nimodipine
Publikováno v:
Neuropeptides. 21:211-223
Injection of endothelin-1 (9 pmol) into the lateral cerebral ventricle of rats produced barrel-rotations, convulsions, tonic hindlimb extensions, facial clonus, and kinetic ataxia for up to 45 min. Quantitative metabolic autoradiographs produced from
Autor:
Paul M. Gross
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 69:1010-1025
From recent morphological and physiological studies of capillaries, I shall review four new or revised concepts about blood–tissue communication in the subfornical organ (SFO) and area postrema (AP). First, the capillary systems of SFO and AP exhib
Autor:
Katharine M. Wall, Paul M. Gross
Publikováno v:
American Journal of Hypertension. 4:444-448
Morphometric and physiological measurements in the parietal cortex of rats with 2-kidney-1-clip renal hypertension and their normotensive controls indicated a 23% increase in capillary bed volume accompanied by a 32% reduction in the rate of cortical