Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Paul M. Brickell"'
Autor:
Paul M. Brickell
Publikováno v:
Molecular Endocrinology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::981a7469cb5e6012310ebadc31ff01d7
https://doi.org/10.1201/9781003076926-2
https://doi.org/10.1201/9781003076926-2
Autor:
Stephen L. Hart, Adrian J. Thrasher, R Anderson, A Michalski, S E Barker, Christine Kinnon, K E Siapati, Paul M. Brickell
Publikováno v:
British Journal of Cancer
Neuroblastoma immunotherapy using cytokine-modified tumour cells has been tested in clinical trials. However, because of the complex nature of antitumour immune responses, a number of therapies may be required for complete tumour eradication and gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::785a1905c8c692f87a62c197ba9b3370
http://europepmc.org/articles/PMC2377114
http://europepmc.org/articles/PMC2377114
Autor:
Michael P. Blundell, Yann Leverrier, Paul M. Brickell, Christine Kinnon, Adrian J. Thrasher, Anne J. Ridley, Roberto Lorenzi
Publikováno v:
The Journal of Immunology. 166:4831-4834
Phagocytosis of apoptotic cells by macrophages and dendritic cells is necessary for clearance of proinflammatory debris and for presentation of viral, tumor, and self Ags. While a number of receptors involved in the cognate recognition of apoptotic c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f7d4bfe8b08303ab442c9d3ba2986e2
https://doi.org/10.4049/jimmunol.166.8.4831
https://doi.org/10.4049/jimmunol.166.8.4831
Publikováno v:
Blood. 95:2943-2946
Interactions between the Wiskott-Aldrich (WAS) protein (WASp), small GTPases, and the cytoskeletal organizing complex Arp2/3 appear to be critical for the transduction of signals from the cell membrane to the actin cytoskeleton in hematopoietic cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::507fd9f6653a3f74f4aa94197493be49
https://doi.org/10.1182/blood.v95.9.2943.009k17_2943_2946
https://doi.org/10.1182/blood.v95.9.2943.009k17_2943_2946
Autor:
Clara AMEIXA, Paul M. BRICKELL
Publikováno v:
Biochemical Journal. 347:485-490
Development of the cellular complexity of the vertebrate neural retina relies on an intricate interplay between extracellular signals and intracellular factors. In particular, transcription factors play a key role in determining the competence of cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::feaa676127b51f89aa90c2ded1ee3755
https://doi.org/10.1042/bj3470485
https://doi.org/10.1042/bj3470485
Autor:
Paul M. Brickell, Judith M. Chessells, Julie C. Webb, Alan H. Simpkins, Natalie Sturt, B. R. Reeves, Irina Golovleva, Helena Kempski
Publikováno v:
Blood. 94:283-290
Rearrangements involving the MLL gene at chromosome 11q23 are associated with leukemia and are present in up to 70% of infant leukemias. Loss of heterozygosity (LOH) has been shown for anonymous polymorphic markers at 11q23 in adult leukemias. To stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0b7f8527d5249eaf625db19a8e81ca1
https://doi.org/10.1182/blood.v94.1.283.413k23_283_290
https://doi.org/10.1182/blood.v94.1.283.413k23_283_290
Autor:
Paul M. Brickell, Rachel L. Moore, Christine Kinnon, Peter Thorogood, Adrian J. Thrasher, Caroline J. Marshall
Publikováno v:
Developmental Dynamics. 215:139-147
The definitive long-term repopulating human hematopoietic stem cell, which seeds the adult blood system, was previously thought to derive from the extra-embryonic yolk sac. However, there is now considerable evidence that in both avian and murine sys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cc487a07b64a6b775c425822efb9f37
https://doi.org/10.1002/(sici)1097-0177(199906)215:2<139::aid-dvdy6>3.0.co
https://doi.org/10.1002/(sici)1097-0177(199906)215:2<139::aid-dvdy6>3.0.co
Autor:
Jane Chalker, Paul M. Brickell, Natalie Sturt, B. R. Reeves, Julie C. Webb, Helena Kempski, Jim MacDonald Clink, Judith M. Chessells
Publikováno v:
British Journal of Haematology. 105:684-689
The t(12;21) is the commonest recurrent translocation in childhood acute lymphoblastic leukaemia (ALL), the presence of which has been suggested to be a good prognostic feature. We have studied 22 childhood cases of B-precursor ALL with this rearrang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76fe040ebc5a048b8f3e8914e781fb2c
https://doi.org/10.1046/j.1365-2141.1999.01425.x
https://doi.org/10.1046/j.1365-2141.1999.01425.x
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 31:383-387
Wiskott-Aldrich Syndrome protein (WASP) is the product of the gene mutated in children with Wiskott-Aldrich Syndrome (WAS). It is a predominantly cytoplasmic protein, expressed only in haematopoietic cells. It binds in vivo to the adaptor proteins Nc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b0ab2356d4f18e9babe26ee08c1a4c5
https://doi.org/10.1016/s1357-2725(98)00118-6
https://doi.org/10.1016/s1357-2725(98)00118-6
Publikováno v:
Molecular Biology Reports. 26:173-177
Wiskott-Aldrich Syndrome (WAS) is a severe X-linked disorder characterised by immune deficiency, thrombocytopenia and eczema, resulting from abnormalities in a range of haematopoietic cell types. The protein that is defective in WAS, named WASP, appe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dde55acd547b82a25434ed8d114aa1bb
https://doi.org/10.1023/a:1006954206151
https://doi.org/10.1023/a:1006954206151