Zobrazeno 1 - 10
of 199
pro vyhledávání: '"Paul M Yen"'
Autor:
Madhulika Tripathi, Karine Gauthier, Reddemma Sandireddy, Jin Zhou, Priyanka Guptta, Suganya Sakthivel, Wei Wen Teo, Yadanar Than Naing, Kabilesh Arul, Keziah Tikno, Sung-Hee Park, Yajun Wu, Lijin Wang, Boon-Huat Bay, Lei Sun, Vincent Giguere, Pierce K.H. Chow, Sujoy Ghosh, Donald P. McDonnell, Paul M. Yen, Brijesh K. Singh
Publikováno v:
Molecular Metabolism, Vol 87, Iss , Pp 101997- (2024)
Objective: Currently, little is known about the mechanism(s) regulating global and specific protein translation during metabolic dysfunction-associated steatohepatitis (MASH; previously known as non-alcoholic steatohepatitis, NASH). Methods: Unbiased
Externí odkaz:
https://doaj.org/article/17f87e3dbde54cfa8579d8857c0fe2d1
Autor:
Benjamin L Farah, Rohit A Sinha, Yajun Wu, Brijesh K Singh, Jin Zhou, Boon-Huat Bay, Paul M Yen
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98155 (2014)
Autophagy recently has been shown to be involved in normal hepatic function and in pathological conditions such as non-alcoholic fatty liver disease. Adrenergic signalling also is an important regulator of hepatic metabolism and function. However, cu
Externí odkaz:
https://doaj.org/article/bc3c012a92f1433ab6ac6332fd7c90f4
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9853 (2010)
Hormonally-regulated histone modifications that govern positive versus negative transcription of target genes are poorly characterized despite their importance for normal and pathological endocrine function. There have been only a few studies examini
Externí odkaz:
https://doaj.org/article/3e8d325fd40e4185a96bca47c3b2e27c
Autor:
Smarajit Chakraborty, Wee Kiat Ong, Winifred W. Y. Yau, Zhihong Zhou, K. N. Bhanu Prakash, Sue-Anne Toh, Weiping Han, Paul M. Yen, Shigeki Sugii
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-13 (2021)
Abstract Background Effective stem cell therapy is dependent on the stem cell quality that is determined by their differentiation potential, impairment of which leads to poor engraftment and survival into the target cells. However, limitations in our
Externí odkaz:
https://doaj.org/article/ca6b50ac2ba14c5889a290b4470f21f9
Publikováno v:
Journal of Hepatology. 78:e174-e175
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d2cced9376748a93ae4d4c44f49b5ef
https://doi.org/10.1016/j.jhep.2023.01.023
https://doi.org/10.1016/j.jhep.2023.01.023
Publikováno v:
Journal of clinical endocrinology and metabolism, 108(3), e36-e37. The Endocrine Society
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::868641eef395d4119de5c88d1f16f239
https://pubmed.ncbi.nlm.nih.gov/36181451
https://pubmed.ncbi.nlm.nih.gov/36181451
Autor:
Paul M. Yen, K. N. Bhanu Prakash, Shigeki Sugii, Wee Kiat Ong, Winifred W. Yau, Weiping Han, Smarajit Chakraborty, Zhihong Zhou, Sue-Anne Toh
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-13 (2021)
Stem Cell Research & Therapy
Stem Cell Research & Therapy
Background Effective stem cell therapy is dependent on the stem cell quality that is determined by their differentiation potential, impairment of which leads to poor engraftment and survival into the target cells. However, limitations in our understa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0028eb259793edb8d1aa4364ac3c3e0
https://doaj.org/article/ca6b50ac2ba14c5889a290b4470f21f9
https://doaj.org/article/ca6b50ac2ba14c5889a290b4470f21f9
Autor:
Rohit A. Sinha, Sangam Rajak, Paul M. Yen, Archana Tewari, Sana Raza, Shivmurat Yadav, Sujoy Ghosh
Publikováno v:
Biochemical and Biophysical Research Communications. 532:570-575
Hepatocellular cancer (HCC) is one of the leading causes of mortality worldwide. Unfortunately, a limited choice of anti-cancer drugs is available for treatment, owing to their minimal efficacy and development of acquired resistance. Autophagy, a cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f94a97d24ca19fa91039606a59c2fd9e
https://doi.org/10.1016/j.bbrc.2020.08.068
https://doi.org/10.1016/j.bbrc.2020.08.068
Publikováno v:
Journal of Endocrinological Investigation. 44:969-977
The homeostatic euthyroid set point of the hypothalamus–pituitary–thyroid axis of any given individual is unique and oscillates narrowly within substantially broader normal population ranges of circulating free thyroxine (FT4) and thyroid-stimula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70a5b3e7447c53c818431b0abe2ecafd
https://doi.org/10.1007/s40618-020-01390-7
https://doi.org/10.1007/s40618-020-01390-7
Autor:
Paul M. Yen, Jin Zhou, Brijesh K. Singh, Reddemma Sandireddy, Keziah Tikno, Madhulika Tripathi
Publikováno v:
Aging (Albany NY)
Although aging in the liver contributes to the development of chronic liver diseases such as NAFLD and insulin resistance, little is known about the molecular and metabolic details of aging in hepatic cells. To examine these issues, we used sequentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3040206b4a963d7a01da6b79972fc0d
https://doi.org/10.18632/aging.103740
https://doi.org/10.18632/aging.103740