Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Paul M Sweetnam"'
PURPOSE: To provide a commentary on our understanding of the role that the Hippo signaling pathway may play in patients with polycystic ovarian syndrome (PCOS) and how this understanding may impact the diagnosis of PCOS. METHODS: We assessed publicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f410c94b7ece196fb68153c75dcc4ba3
https://europepmc.org/articles/PMC6150890/
https://europepmc.org/articles/PMC6150890/
Autor:
Edward J. Hunnicutt, William G. Stirtan, David G. Osterman, Ian Taylor, James A. Landro, Peter Rae, Paul M. Sweetnam, James Kristie
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 44:273-289
Over the past decade, high throughput screening (HTS) has become the focal point for discovery programs within the pharmaceutical industry. The role of this discipline has been and remains the rapid and efficient identification of lead chemical matte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78636a8e4d7216e3e74db5e21b8849ac
https://doi.org/10.1016/s1056-8719(00)00108-8
https://doi.org/10.1016/s1056-8719(00)00108-8
HIV Type 1 Infection of Human Cortical Neuronal Cells: Enhancement by Select Neuronal Growth Factors
Publikováno v:
AIDS Research and Human Retroviruses. 10:1593-1596
Neuronal cells in culture respond to neuronal growth factors by secondary cellular pathways similar to those described for activation of lymphocytes and macrophages. In HIV-1-infected T lymphocytes and in macrophages, these pathways were shown to con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86fbe4e220bf39c64a4faef7210f2739
https://doi.org/10.1089/aid.1994.10.1593
https://doi.org/10.1089/aid.1994.10.1593
Autor:
W. J. Kinnier, Christopher H. Price, Paul M. Sweetnam, Jean Lancaster, Lisa Caldwell, Barbara McMillan, Charles Bauer
Publikováno v:
Journal of Natural Products. 56:441-455
Radioligand receptor binding has been used extensively to identify and characterize a host of receptors and enzymes targeting virtually every therapeutic area. Many drug discovery programs have been based on the utilization of radioligand receptor bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::689d41314bfef8c74de69c2b4845798e
https://doi.org/10.1021/np50094a001
https://doi.org/10.1021/np50094a001
Publikováno v:
Brain research. 764(1-2)
Using a degenerate PCR based approach, a fragment of the novel G protein-coupled receptor, VTR 15–20, was identified from the rat ventral tegmentum. Hybridization screening and RACE PCR were employed to isolate the full length clone. The cDNA encod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27797af0644a3f301fcbdbffca63f555
https://pubmed.ncbi.nlm.nih.gov/9295203
https://pubmed.ncbi.nlm.nih.gov/9295203
Autor:
Ronald S. Duman, Maura E. Charlton, Paul M. Sweetnam, Rosemarie Terwilliger, Lawrence W. Fitzgerald, Eric J. Nestler
Publikováno v:
Journal of neurochemistry. 68(1)
Ethanol dependence and tolerance involve perturbation of GABAergic neurotransmission. Previous studies have demonstrated that ethanol treatment regulates the function and expression of GABAA receptors throughout the CNS. Conceivably, changes in recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0dce5a6b62bb3cefb16895013f318bc
https://pubmed.ncbi.nlm.nih.gov/8978717
https://pubmed.ncbi.nlm.nih.gov/8978717
Publikováno v:
Journal of neurochemistry. 63(5)
The structure of N-acetylaspartylglutamate (NAAG) suggests this neuronal dipeptide as a candidate for interaction with discrete subclasses of ionotropic and metabotropic acidic amino acid receptors. A substantial difficulty in the assay of these inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e5aa97f1e7d29995657305670244e66
https://pubmed.ncbi.nlm.nih.gov/7523599
https://pubmed.ncbi.nlm.nih.gov/7523599
Autor:
Mark A. Coggiano, Henrietta Kulaga, Paul M. Sweetnam, Solomon H. Snyder, Richard T. Wyatt, M.E. Truckenmiller
Publikováno v:
AIDS research and human retroviruses. 9(5)
HCN-1A is a human cerebral cortical neuronal cell line having properties consistent with cells of immature neuronal origin. This article details evidence for productive low-level infection of HCN-1A cells with human immunodeficiency virus type 1 (HIV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41b48186208c00e4c763248ca6ee1cf7
https://pubmed.ncbi.nlm.nih.gov/8318271
https://pubmed.ncbi.nlm.nih.gov/8318271
Autor:
Michael Jaye, Barry J. Brass, Linda A. White, Henry R. Sanon, Paul M. Sweetnam, Scott R. Whittemore
Publikováno v:
Journal of neurochemistry. 57(1)
When spinal cord cultures from embryonic day 12 rats were cultured at low density, both acidic and basic fibroblast growth factors significantly increased neuronal survival and neurite outgrowth in a dose-dependent manner. The effects of acidic fibro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70ba121ee6e86a08b49e3ce208e9a8b7
https://pubmed.ncbi.nlm.nih.gov/1711096
https://pubmed.ncbi.nlm.nih.gov/1711096
Autor:
Jeremy P. Grierson, Herbert M. Geller, Peter Gallombardo, Roseann Ventimiglia, John F. Tallman, Paul M. Sweetnam
Publikováno v:
Neuroscience letters. 115(2-3)
γ-Aminobutyric acid (GABA) is the major inhibitory transmitter in the mammalian central nervous system (CNS) and an understanding of the development of receptors for this compound is of considerable interest. In this study, 3 monoclonal antibodies d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8e29c5229e1ed62dfb398e3cdcffebc
https://pubmed.ncbi.nlm.nih.gov/1700340
https://pubmed.ncbi.nlm.nih.gov/1700340