Zobrazeno 1 - 10
of 574
pro vyhledávání: '"Paul M Stewart"'
Autor:
Zaki K Hassan-Smith, Carl Jenkinson, David J Smith, Ivan Hernandez, Stuart A Morgan, Nicola J Crabtree, Neil J Gittoes, Brian G Keevil, Paul M Stewart, Martin Hewison
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0170665 (2017)
Age-associated decline in muscle function represents a significant public health burden. Vitamin D-deficiency is also prevalent in aging subjects, and has been linked to loss of muscle mass and strength (sarcopenia), but the precise role of specific
Externí odkaz:
https://doaj.org/article/292b545db1ba400eb583e4542813c297
Autor:
Rachel K Crowley, Michael W O'Reilly, Iwona J Bujalska, Zaki K Hassan-Smith, Jonathan M Hazlehurst, Danielle R Foucault, Paul M Stewart, Jeremy W Tomlinson
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163777 (2016)
AimsThe aim of this study was to assess depot-specific expression and secretion of secreted frizzled-related protein 2 (sFRP2) by adipose tissue and its effect on adipocyte biology. We measured serum sFRP2 concentrations in 106 patients in vivo to ex
Externí odkaz:
https://doaj.org/article/9dc0174875204f2ea76af45ad0904c14
Autor:
Adeeba Ahmed, Elizabeth Rabbitt, Theresa Brady, Claire Brown, Peter Guest, Iwona J Bujalska, Craig Doig, Philip N Newsome, Stefan Hubscher, Elwyn Elias, David H Adams, Jeremy W Tomlinson, Paul M Stewart
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e29531 (2012)
Non alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of the metabolic syndrome. NAFLD represents a spectrum of liver disease ranging from reversible hepatic steatosis, to non alcoholic steato-hepatitis (NASH) and cirrhosis. The pote
Externí odkaz:
https://doaj.org/article/5957337d10514e10a983dd8bfec49c31
Autor:
Thahira J Rahman, Elizabeth A Walker, Bongani M Mayosi, Darroch H Hall, Peter J Avery, John M C Connell, Hugh Watkins, Paul M Stewart, Bernard Keavney
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23248 (2011)
OBJECTIVE:The combined thickness of the intima and media of the carotid artery (carotid intima-medial thickness, CIMT) is associated with cardiovascular disease and stroke. Previous studies indicate that carotid intima-medial thickness is a significa
Externí odkaz:
https://doaj.org/article/7534d56f1c9a4867802e33e16f1abd34
Autor:
Laura L Gathercole, Stuart A Morgan, Iwona J Bujalska, David Hauton, Paul M Stewart, Jeremy W Tomlinson
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26223 (2011)
Patients with glucocorticoid (GC) excess, Cushing's syndrome, develop a classic phenotype characterized by central obesity and insulin resistance. GCs are known to increase the release of fatty acids from adipose, by stimulating lipolysis, however, t
Externí odkaz:
https://doaj.org/article/66eb4965a0194e279a30d6d9c3d451a5
Autor:
Nantia Othonos, Riccardo Pofi, Anastasia Arvaniti, Sarah White, Ilaria Bonaventura, Nikolaos Nikolaou, Ahmad Moolla, Thomas Marjot, Roland H. Stimson, André P. van Beek, Martijn van Faassen, Andrea M. Isidori, Elizabeth Bateman, Ross Sadler, Fredrik Karpe, Paul M. Stewart, Craig Webster, Joanne Duffy, Richard Eastell, Fatma Gossiel, Thomas Cornfield, Leanne Hodson, K. Jane Escott, Andrew Whittaker, Ufuk Kirik, Ruth L. Coleman, Charles A. B. Scott, Joanne E. Milton, Olorunsola Agbaje, Rury R. Holman, Jeremy W. Tomlinson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Glucocorticoids prescribed to limit inflammation, have significant adverse effects. Here the authors show that co-administration of AZD4017 with prednisolone in men is a potential strategy to limit adverse glucocorticoid effects.
Externí odkaz:
https://doaj.org/article/d5729cc721e9453cb5043aab11c131a3
Autor:
Rahul Y. Mahida, Siân Lax, Christopher R. Bassford, Aaron Scott, Dhruv Parekh, Rowan S. Hardy, Babu Naidu, Michael A. Matthay, Paul M. Stewart, Mark C. Cooper, Gavin D. Perkins, David R. Thickett
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundAcute Respiratory Distress Syndrome (ARDS) is a devastating pulmonary inflammatory disorder, commonly precipitated by sepsis. Glucocorticoids are immunomodulatory steroids that can suppress inflammation. Their anti-inflammatory properties w
Externí odkaz:
https://doaj.org/article/79837288f2f145448fc78353241ec42d
Addressing ecologists, legislators, lawyers, and industrialists alike, Ruth Patrick asks what has been accomplished with the millions of dollars spent on upgrading our surface waters. Has the water improved in spite of the fact that the crayfish, sna
Autor:
Charles Jonathan Peter Snart, Diane Erin Threapleton, Claire Keeble, Elizabeth Taylor, Dagmar Waiblinger, Stephen Reid, Nisreen A. Alwan, Dan Mason, Rafaq Azad, Janet Elizabeth Cade, Nigel A. B. Simpson, Sarah Meadows, Amanda McKillion, Gillian Santorelli, Amanda H. Waterman, Michael Zimmermann, Paul M. Stewart, John Wright, Mark Mon-Williams, Darren Charles Greenwood, Laura J. Hardie
Publikováno v:
BMC Medicine, Vol 18, Iss 1, Pp 1-11 (2020)
Abstract Background Severe iodine insufficiency in pregnancy has significant consequences, but there is inadequate evidence to indicate what constitutes mild or moderate insufficiency, in terms of observed detrimental effects on pregnancy or birth ou
Externí odkaz:
https://doaj.org/article/0ebb4878455b4f7fa34843605f26436e
Autor:
Yasir S. Elhassan, Fizzah Iqbal, Wiebke Arlt, Stephanie E. Baldeweg, Miles Levy, Paul M. Stewart, John Wass, Sue Pavord, D. Aled Rees, Cristina L. Ronchi
Publikováno v:
Clinical Endocrinology. 98:766-778
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06ef29f4b67dc22a93f4bc8d54ba80e6
https://doi.org/10.1111/cen.14881
https://doi.org/10.1111/cen.14881