Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Paul M Howley"'
Autor:
Jessamine E Hazlewood, Troy Dumenil, Thuy T Le, Andrii Slonchak, Stephen H Kazakoff, Ann-Marie Patch, Lesley-Ann Gray, Paul M Howley, Liang Liu, John D Hayball, Kexin Yan, Daniel J Rawle, Natalie A Prow, Andreas Suhrbier
Publikováno v:
PLoS Pathogens, Vol 17, Iss 1, p e1009215 (2021)
Poxvirus systems have been extensively used as vaccine vectors. Herein a RNA-Seq analysis of intramuscular injection sites provided detailed insights into host innate immune responses, as well as expression of vector and recombinant immunogen genes,
Externí odkaz:
https://doaj.org/article/51873aa015164c15b3f0332db477b26b
Publikováno v:
Expert Review of Vaccines, Vol 17, Iss 10, Pp 925-934 (2018)
Introduction: With the increasing number of vaccines and vaccine-preventable diseases, the pressure to generate multi-valent and multi-pathogen vaccines grows. Combining individual established vaccines to generate single-shot formulations represents
Externí odkaz:
https://doaj.org/article/2dbf7c5aaf93487fa930b4b90a8ff06c
Autor:
Wilson Nguyen, Eri Nakayama, Kexin Yan, Bing Tang, Thuy T. Le, Liang Liu, Tamara H. Cooper, John D. Hayball, Helen M. Faddy, David Warrilow, Richard J. N. Allcock, Jody Hobson-Peters, Roy A. Hall, Daniel J. Rawle, Viviana P. Lutzky, Paul Young, Nidia M. Oliveira, Gunter Hartel, Paul M. Howley, Natalie A. Prow, Andreas Suhrbier
Publikováno v:
Vaccines, Vol 8, Iss 2, p 209 (2020)
Chikungunya virus (CHIKV), Ross River virus (RRV), o’nyong nyong virus (ONNV), Mayaro virus (MAYV) and Getah virus (GETV) represent arthritogenic alphaviruses belonging to the Semliki Forest virus antigenic complex. Antibodies raised against one of
Externí odkaz:
https://doaj.org/article/ab91253b909a4655ac9a7f198f2a6b40
Publikováno v:
Viruses, Vol 6, Iss 10, Pp 3787-3808 (2014)
Vaccinia virus (VACV) has achieved unprecedented success as a live viral vaccine for smallpox which mitigated eradication of the disease. Vaccinia virus has a complex virion morphology and recent advances have been made to answer some of the key outs
Externí odkaz:
https://doaj.org/article/8016ecaabbe34456a2955a6e7733d0b5
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1139
Fowlpox virus (FPV) is a double-stranded DNA virus with a history of use as a live attenuated vaccine in commercial poultry production systems. FPV is also highly amenable to genetic engineering, with a large cloning capacity and many nonessential si
Autor:
Danièle Spehner, Paul M. Howley, Bernard A. P. Lafont, Robert Drillien, Martin A. Billeter, Karin Kaelin
Publikováno v:
Journal of Virological Methods. 79:65-74
Measles virus encodes three proteins required for the encapsidation, transcription and replication of viral genomes. The genes for these proteins have been inserted into the vaccinia virus genome together with the gene for the bacteriophage T7 RNA po
Publikováno v:
Virology. 232(2):260-268
Measles virus nucleoprotein encoded from the vaccinia virus genome assembles into nucleocapsids similar in many respects to those observed during a natural measles virus infection. The influence of the measles virus phosphoprotein on nucleocapsid ass
Autor:
John A. Gatehouse, Paul M. Howley
Publikováno v:
Plant Molecular Biology. 33:175-180
This paper describes a target sequence for a pea seed nuclear DNA-binding protein (of Pisum sativum) present at the cell expansion phase. Electromobility shift assays as well as in situ copper-phenanthroline footprinting have shown that this protein
Publikováno v:
Gene. 172(2)
A vaccinia virus (VV) transfer vector is described which enables integration of heterologous sequences into the I4L locus (ribonucleotide reductase-encoding gene) through co-insertion of a GUS selection marker. I4L- VV recombinants formed blue plaque
Autor:
Natalie A. Prow, Liang Liu, Eri Nakayama, Tamara H. Cooper, Kexin Yan, Preethi Eldi, Jessamine E. Hazlewood, Bing Tang, Thuy T. Le, Yin Xiang Setoh, Alexander A Khromykh, Jody Hobson-Peters, Kerrilyn R. Diener, Paul M. Howley, John D. Hayball, Andreas Suhrbier
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Zika and chikungunya virus are co-circulating in many regions and currently there is no approved vaccine for either virus. Here, the authors engineer one vaccinia virus based vaccine for both, Zika and chikungunya, and show protection from infection
Externí odkaz:
https://doaj.org/article/fb33c22d0fd945c1b4999adae6928f2c