Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Paul M Airs"'
Publikováno v:
eLife, Vol 12 (2023)
Nematode excretory-secretory (ES) products are essential for the establishment and maintenance of infections in mammals and are valued as therapeutic and diagnostic targets. While parasite effector proteins contribute to host immune evasion and anthe
Externí odkaz:
https://doaj.org/article/160b029e1dcd4d70bc652597fe8829f2
Autor:
Paul M Airs, Kathy Vaccaro, Kendra J Gallo, Nathalie Dinguirard, Zachary W Heimark, Nicolas J Wheeler, Jiaye He, Kurt R Weiss, Nathan E Schroeder, Jan Huisken, Mostafa Zamanian
Publikováno v:
PLoS Pathogens, Vol 18, Iss 4, p e1010399 (2022)
Lymphatic filariasis (LF) is a chronic debilitating neglected tropical disease (NTD) caused by mosquito-transmitted nematodes that afflicts over 60 million people. Control of LF relies on routine mass drug administration with antiparasitics that clea
Externí odkaz:
https://doaj.org/article/49c5fe9ca81f4f17a907957b2ba33937
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 11, p e0008869 (2020)
Filarial parasitic nematodes (Filarioidea) cause substantial disease burden to humans and animals around the world. Recently there has been a coordinated global effort to generate, annotate, and curate genomic data from nematode species of medical an
Externí odkaz:
https://doaj.org/article/64913c8e992d4e2bacfb8e895689ff30
Autor:
Nicolas J Wheeler, Zachary W Heimark, Paul M Airs, Alexis Mann, Lyric C Bartholomay, Mostafa Zamanian
Publikováno v:
PLoS Biology, Vol 18, Iss 6, p e3000723 (2020)
Lymphatic filariasis (LF) afflicts over 60 million people worldwide and leads to severe pathological outcomes in chronic cases. The nematode parasites (Nematoda: Filarioidea) that cause LF require both arthropod (mosquito) intermediate hosts and mamm
Externí odkaz:
https://doaj.org/article/fd8b72696ec8410b9f3d364de4914fb7
Autor:
Yashdeep Phanse, Brendan M Dunphy, Jillian L Perry, Paul M Airs, Cynthia C H Paquette, Jonathan O Carlson, Jing Xu, J Christopher Luft, Joseph M DeSimone, Barry J Beaty, Lyric C Bartholomay
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 5, p e0003735 (2015)
Mosquito-borne diseases continue to remain major threats to human and animal health and impediments to socioeconomic development. Increasing mosquito resistance to chemical insecticides is a great public health concern, and new strategies/technologie
Externí odkaz:
https://doaj.org/article/8e5515e4da4b4fb7a75741bcc0b44112
Autor:
Cynthia C H Paquette, Yashdeep Phanse, Jillian L Perry, Irma Sanchez-Vargas, Paul M Airs, Brendan M Dunphy, Jing Xu, Jonathan O Carlson, J Christopher Luft, Joseph M DeSimone, Lyric C Bartholomay, Barry J Beaty
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 5, p e0003745 (2015)
BACKGROUND:Nanotechnology offers great potential for molecular genetic investigations and potential control of medically important arthropods. Major advances have been made in mammalian systems to define nanoparticle (NP) characteristics that conditi
Externí odkaz:
https://doaj.org/article/a5da1606b18b440580ffa96192e587c8
Publikováno v:
Insects; Volume 14; Issue 6; Pages: 556
In mosquitoes, the utilization of RNAi for functional genetics is widespread, usually mediated through introduced double-stranded RNAs (dsRNAs) with sequence identity to a gene of interest. However, RNAi in mosquitoes is often hampered by inconsisten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::4adcb0d91edd09f8c77a3124238a05ec
Publikováno v:
Antimicrobial Agents and Chemotherapy. 67
The diversification of anthelmintic targets and mechanisms of action will help ensure the sustainable control of nematode infections in response to the growing threat of drug resistance. G protein-coupled receptors (GPCRs) are established drug target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b352cbb2ea736131d2dd4bc3be98476f
https://doi.org/10.1128/aac.01188-22
https://doi.org/10.1128/aac.01188-22
WormWatch: Park soil surveillance reveals extensive Toxocara contamination across the UK and Ireland
Publikováno v:
Airs, P M, Brown, C, Gardiner, E, Maciag, L, Adams, J P & Morgan, E R 2023, ' WormWatch: Park soil surveillance reveals extensive Toxocara contamination across the UK and Ireland ', Veterinary Record, vol. 192, no. 1, e2341 . https://doi.org/10.1002/vetr.2341
BackgroundToxocarosis is a globally distributed zoonotic disease, but sources of infection are not well documented over large geographical scales. To determine levels of environmental contamination, soil from 142 parks and recreational areas across t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c10e355ceceb8e58f71eb56e1483dbfb
https://pure.qub.ac.uk/en/publications/5b4a4b51-518c-4378-a365-c35499864852
https://pure.qub.ac.uk/en/publications/5b4a4b51-518c-4378-a365-c35499864852
Autor:
Paul M Airs, Andrews CL Safalaoh, Winchester Mvula, Patience Khonje, Jaiver Ventura-Cordero, Taro Takahashi, Patson Nalivata, Jan Van Wyk, Eric R Morgan
Smallholder goat production plays a major role in rural livelihoods and food security in Malawi. While goat production is closely linked to small scale local markets for slaughter and butchering the perspectives of butchers and their potential as a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88f39958636d9fff91bd744ba0025267
https://doi.org/10.21203/rs.3.rs-1878863/v1
https://doi.org/10.21203/rs.3.rs-1878863/v1