Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Paul M, Jenkins"'
Autor:
Hao Liu, René N Caballero-Florán, Ty Hergenreder, Tao Yang, Jacob M Hull, Geng Pan, Ruonan Li, Macy W Veling, Lori L Isom, Kenneth Y Kwan, Z Josh Huang, Peter G Fuerst, Paul M Jenkins, Bing Ye
Publikováno v:
PLoS Biology, Vol 21, Iss 4, p e3002078 (2023)
Down syndrome (DS) is caused by the trisomy of human chromosome 21 (HSA21). A major challenge in DS research is to identify the HSA21 genes that cause specific symptoms. Down syndrome cell adhesion molecule (DSCAM) is encoded by a HSA21 gene. Previou
Externí odkaz:
https://doaj.org/article/5435da0bc2f449e6ab932c4de909e9f3
Autor:
Julie P. Gupta, Paul M. Jenkins
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Neuronal ankyrin-B is an intracellular scaffolding protein that plays multiple roles in the axon. By contrast, relatively little is known about the function of ankyrin-B in dendrites, where ankyrin-B is also localized in mature neurons. Recently, we
Externí odkaz:
https://doaj.org/article/28a93bfee2184493977172c2fb36da4e
Autor:
Merci N. Best, Yunu Lim, Nina N. Ferenc, Nayoung Kim, Lia Min, Dora Bigler Wang, Kamyar Sharifi, Anna E. Wasserman, Sloane A. McTavish, Karsten H. Siller, Marieke K. Jones, Paul M. Jenkins, James W. Mandell, George S. Bloom
Publikováno v:
Journal of Alzheimer's Disease. :1-17
Background: In Alzheimer’s disease (AD) brain, neuronal polarity and synaptic connectivity are compromised. A key structure for regulating polarity and functions of neurons is the axon initial segment (AIS), which segregates somatodendritic from ax
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Regulation of cardiac physiology is well known to occur through the action of kinases that reversibly phosphorylate ion channels, calcium handling machinery, and signaling effectors. However, it is becoming increasingly apparent that palmitoylation o
Externí odkaz:
https://doaj.org/article/9c85599cc56e4f50a68e0f03b4e4681a
Autor:
Christian Thome, Jan Maximilian Janssen, Seda Karabulut, Claudio Acuna, Elisa D’Este, Stella J. Soyka, Konrad Baum, Michael Bock, Nadja Lehmann, Masashi Hasegawa, Dan Alin Ganea, Chloé Maëlle Benoit, Jan Gründemann, Christian Schultz, Vann Bennett, Paul M. Jenkins, Maren Engelhardt
The axon initial segment (AIS) constitutes not only the site of action potential initiation, but also a hub for activity-dependent modulation of output generation. Recent studies shedding light on AIS function used predominantlypost hocapproaches sin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ba62b28fdc70d245e6a2a3a43ec89c6
https://doi.org/10.1101/2023.02.01.525891
https://doi.org/10.1101/2023.02.01.525891
Autor:
Andrew D. Nelson, Paul M. Jenkins
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
Neurons are highly specialized cells of the nervous system that receive, process and transmit electrical signals critical for normal brain function. Here, we review the intricate organization of axonal membrane domains that facilitate rapid action po
Externí odkaz:
https://doaj.org/article/053e84ad2cf041bc932dbe2f2cba0fb5
Autor:
René N. Caballero-Florán, Mounir Bendahmane, Julie P. Gupta, Xiaohuan Chen, Xiaojun Wu, Alina Morales, Arun Anantharam, Paul M. Jenkins
Publikováno v:
Neuroscience Letters. 800:137129
Publikováno v:
Injury Epidemiology, Vol 8, Iss 1, Pp 1-9 (2021)
Injury Epidemiology
Injury Epidemiology
Background While statistics related to occupational injuries exist at state and national levels, there are notable difficulties with using these to understand non-fatal injuries trends in agriculture, forestry, and commercial fishing. This paper desc
Autor:
Andrew D. Nelson, Amanda M. Catalfio, Julie M. Gupta, Lia Min, Rene N. Caballero-Floran, Kendall P. Dean, Carina C. Elvira, Kimberly D. Derderian, Henry Kyoung, Atehsa Sahagun, Stephan J. Sanders, Kevin J. Bender, Paul M. Jenkins
Dysfunction in sodium channels and their ankyrin scaffolding partners have both been implicated in neurodevelopmental disorders, including autism spectrum disorder (ASD). In particular, the genes SCN2A, which encodes the sodium channel NaV1.2, and AN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3da3ec1831db7357a03e80a8f144d952
https://doi.org/10.1101/2022.05.31.494205
https://doi.org/10.1101/2022.05.31.494205
Publikováno v:
Journal of occupational and environmental medicine. 64(3)
This research reports on the health status, including chronic disease risk factors, among Maine loggers.Loggers completed a survey and health screenings were held across Maine, collecting data on a variety of health endpoints.Seventy-five loggers par