Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Paul Loria"'
Publikováno v:
ChemInform. 27
Ten ' bisquinolones' were prepared by joining two molecules of norfloxacin, or 1,8-naphthyridine and benzo [c][1,8] naphthyridine derivatives, with various aliphatic linkers. These were tested against 17 bacteria strains but none showed more than sli
Publikováno v:
ChemInform. 27
Some reactions of 1-acetylimino-3-methyl-1H-2-benzopyran-4-carbonitrile with nitrogen nucleophiles are reported. This is a versatile intermediate and leads to isoquino [1,2-b] quinazoline (with methyl anthranilate ), [1,2,4] triazolo [5,1-a] isoquino
Publikováno v:
ChemInform. 30
The reaction of the isocoumarin derivative 1-acetylimino-3-methyl-1H-2-benzopyran-4-carbonitrile (1a) with aromatic ortho diamines provides entry to the benzimidazo[2,1-a]isoquinoline and related systems. Various conversions of the methyl and cyano g
Autor:
Michael Foley, Gabriele M. König, Marion Gurrath, Gulcan Kocak, Gregory M. Neumann, Leann Tilley, Anthony D. Wright, Paul Loria, Huiqin Wang
Publikováno v:
Journal of medicinal chemistry. 44(6)
A series of terpene isonitriles, isolated from marine sponges, have previously been shown to exhibit antimalarial activities. Molecular modeling studies employing 3D-QSAR with receptor modeling methodologies performed with these isonitriles showed th
Publikováno v:
The Biochemical journal. 339
The malaria parasite feeds by degrading haemoglobin in an acidic food vacuole, producing free haem moieties as a by-product. The haem in oxyhaemoglobin is oxidized from the Fe(II) state to the Fe(III) state with the consequent production of an equimo
Publikováno v:
Australian Journal of Chemistry. 51:941
The reaction of the isocoumarin derivative 1-acetylimino-3-methyl-1H-2-benzopyran-4-carbonitrile (1a) with aromatic ortho diamines provides entry to the benzimidazo[2,1-a]isoquinoline and related systems. Various conversions of the methyl and cyano g
Publikováno v:
Australian Journal of Chemistry. 49:255
Ten ' bisquinolones' were prepared by joining two molecules of norfloxacin, or 1,8-naphthyridine and benzo [c][1,8] naphthyridine derivatives, with various aliphatic linkers. These were tested against 17 bacteria strains but none showed more than sli
Publikováno v:
Australian Journal of Chemistry. 49:485
Some reactions of 1-acetylimino-3-methyl-1H-2-benzopyran-4-carbonitrile with nitrogen nucleophiles are reported. This is a versatile intermediate and leads to isoquino [1,2-b] quinazoline (with methyl anthranilate ), [1,2,4] triazolo [5,1-a] isoquino