Zobrazeno 1 - 10
of 768
pro vyhledávání: '"Paul Little"'
Autor:
Miriam Santer, Megan Lawrence, Sarah Pyne, Susanne Renz, Beth L Stuart, Tracey Sach, Matthew Ridd, Kim S Thomas, Jacqueline Nuttall, Natalia Permyakova, Zina Eminton, Nick Francis, Paul Little, Ingrid Muller, Irene Soulsby, Karen Thomas, Gareth Griffiths, Alison M Layton
Publikováno v:
Health Technology Assessment, Vol 28, Iss 56 (2024)
Background Acne is common, can cause significant impact on quality of life and is a frequent reason for long-term antibiotic use. Spironolactone has been prescribed for acne in women for many years, but robust evidence is lacking. Objective To evalua
Externí odkaz:
https://doaj.org/article/d1aa9dfe8a574e4080bf0fbe58d4f066
Autor:
Isabel Reading, Jeremy Jones, Gillian Watson, Paul Little, Michael Moore, Carl R May, Suzanne Hagen, Doreen McClurg, Karen Guerrero, Jacqui Prieto, Nina Wilson, Carol Shields, Mandy Fader, Bridget Clancy, Margaret Macaulay, Thomas J Chadwick, Brian S Buckley, Rajvinder Khasriya, Alaa Abouhajar, Catherine P James, Nicola Goudie, Sylvia Dickson, Miriam R Avery, Jackie Broadbridge, Alan Cottenden, Cathy Murphy, Anthony Timoney, Sandra A Wilks
Publikováno v:
BMJ Open, Vol 14, Iss 8 (2024)
Introduction Evaluating the safety and acceptability of reusing catheters for intermittent catheterisation (IC) is one of the top 10 continence research priorities identified by the UK James Lind Alliance Priority Setting Partnership in 2008. There a
Externí odkaz:
https://doaj.org/article/3e2962596cd24d109aae3e5ba63b6f6b
Autor:
Imran Khan, Stephanie J. C. Taylor, Clare Robinson, Elisavet Moschopoulou, Paul McCrone, Liam Bourke, Mohamed Thaha, Kamaldeep Bhui, Derek Rosario, Damien Ridge, Sheila Donovan, Ania Korszun, Paul Little, Adrienne Morgan, Olivier Quentin, Rebecca Roylance, Peter White, Trudie Chalder
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-15 (2024)
Abstract Background Two million people in the UK are living with or beyond cancer and a third of them report poor quality of life (QoL) due to problems such as fatigue, fear of cancer recurrence, and concerns about returning to work. We aimed to deve
Externí odkaz:
https://doaj.org/article/f71fa4c10e20413487f919f1ce0ddd68
Autor:
Joseph F. Standing, Laura Buggiotti, Jose Afonso Guerra-Assuncao, Maximillian Woodall, Samuel Ellis, Akosua A. Agyeman, Charles Miller, Mercy Okechukwu, Emily Kirkpatrick, Amy I. Jacobs, Charlotte A. Williams, Sunando Roy, Luz M. Martin-Bernal, Rachel Williams, Claire M. Smith, Theo Sanderson, Fiona B. Ashford, Beena Emmanuel, Zaheer M. Afzal, Adrian Shields, Alex G. Richter, Jienchi Dorward, Oghenekome Gbinigie, Oliver Van Hecke, Mark Lown, Nick Francis, Bhautesh Jani, Duncan B. Richards, Najib M. Rahman, Ly-Mee Yu, Nicholas P. B. Thomas, Nigel D. Hart, Philip Evans, Monique Andersson, Gail Hayward, Kerenza Hood, Jonathan S. Nguyen-Van-Tam, Paul Little, F. D. Richard Hobbs, Saye Khoo, Christopher Butler, David M. Lowe, Judith Breuer, PANORAMIC Virology Group
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Viral clearance, antibody response and the mutagenic effect of molnupiravir has not been elucidated in at-risk populations. Non-hospitalised participants within 5 days of SARS-CoV-2 symptoms randomised to receive molnupiravir (n = 253) or Us
Externí odkaz:
https://doaj.org/article/01afce3eddb24d8aa3b7e67fa19987db
Autor:
Ben Ainsworth, Jeremy Horwood, Scott R. Walter, Sascha Miller, Melanie Chalder, Frank De Vocht, James Denison-Day, Martha M. C. Elwenspoek, Helen J. Curtis, Chris Bates, Amir Mehrkar, Seb Bacon, Ben Goldacre, The OpenSAFELY Collaborative, Pippa Craggs, Richard Amlôt, Nick Francis, Paul Little, John Macleod, Michael Moore, Kate Morton, Cathy Rice, Jonathan Sterne, Beth Stuart, Lauren Towler, Merlin L. Willcox, Lucy Yardley
Publikováno v:
Implementation Science, Vol 18, Iss 1, Pp 1-13 (2023)
Abstract Background Germ Defence ( www.germdefence.org ) is an evidence-based interactive website that promotes behaviour change for infection control within households. To maximise the potential of Germ Defence to effectively reduce the spread of CO
Externí odkaz:
https://doaj.org/article/b4cdb07d7a8548fa9e7d0eb16f55da29
Autor:
Merijn H. Rijk, Tamara N. Platteel, Geert-Jan Geersing, Monika Hollander, Bert L. G. P. Dalmolen, Paul Little, Frans H. Rutten, Maarten van Smeden, Roderick P. Venekamp
Publikováno v:
Diagnostic and Prognostic Research, Vol 7, Iss 1, Pp 1-8 (2023)
Abstract Background Community-acquired lower respiratory tract infections (LRTI) are common in primary care and patients at particular risk of adverse outcomes, e.g., hospitalisation and mortality, are challenging to identify. LRTIs are also linked t
Externí odkaz:
https://doaj.org/article/b169b12f06b84b75be224477308d479a
Autor:
Mark Lown, Kirsten Smith, Ingrid Muller, Catherine Woods, Emma Maund, Kirsty Rogers, Taeko Becque, Gail Hayward, Michael Moore, Paul Little, Margaret Glogowska, Alastair Hay, Beth Stuart, Efi Mantzourani, Christopher R Wilcox, Natalie Thompson, Nick A Francis
Publikováno v:
Journal of Medical Internet Research, Vol 26, p e59420 (2024)
Externí odkaz:
https://doaj.org/article/19da0e155d8541e5a3f96281d111cab3
Autor:
Paul Little, Frans H Rutten, Geert-Jan Geersing, Maarten van Smeden, Roderick P Venekamp, Tamara N Platteel, Merijn H Rijk, Teun M C van den Berg
Publikováno v:
BMJ Open, Vol 14, Iss 3 (2024)
Objective To identify and synthesise relevant existing prognostic factors (PF) and prediction models (PM) for hospitalisation and all-cause mortality within 90 days in primary care patients with acute lower respiratory tract infections (LRTI).Design
Externí odkaz:
https://doaj.org/article/10d3cca2b78545a982b7cf152a2d30e1
Autor:
Christian Mallen, Jennifer Bostock, Taeko Becque, Beth Stuart, Jeremy Howick, Jane Vennik, Paul Little, Matthew J Ridd, Kirsty Garfield, Paul H Lee, Helen Atherton, Felicity L Bishop, Nazrul Islam, Michelle E Robinson, Geraldine M Leydon, Emma Teasdale, Jacqui Nuttall, Leanne Morrison, Lorna Clarson, Hazel A Everitt, Amy Herbert, Nadia Cross, Rachel Dewar-Haggart, Sebastien Pollet
Publikováno v:
BMJ Open, Vol 14, Iss 3 (2024)
Introduction Effective communication can help optimise healthcare interactions and patient outcomes. However, few interventions have been tested clinically, subjected to cost-effectiveness analysis or are sufficiently brief and well-described for imp
Externí odkaz:
https://doaj.org/article/58abd7c064cc4fb1ba3330373910ad92
Autor:
Gemma Mas-Dalmau, María José Pérez-Lacasta, Pablo Alonso-Coello, Pedro Gorrotxategi-Gorrotxategi, Emma Argüelles-Prendes, Oscar Espinazo-Ramos, Teresa Valls-Duran, María Encarnación Gonzalo-Alonso, María Pilar Cortés-Viana, Tatiana Menéndez-Bada, Marta Esther Vázquez-Fernández, Ana Isabel Pérez-Hernández, Laura Muñoz-Ortiz, Carmen Villanueva-López, Paul Little, Mariam de la Poza-Abad, Misericòrdia Carles-Lavila, on behalf of the DAP Paediatrics Group
Publikováno v:
BMC Pediatrics, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Background Antibiotic prescription for respiratory tract infections (RTIs) in children attending primary care centres is almost double that predicted according to bacterial prevalence. Delayed antibiotic prescription (DAP) is designed to dep
Externí odkaz:
https://doaj.org/article/3308036cc5ec46548d2eee67d158f9c4