Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Paul Levitan"'
Publikováno v:
Journal of Medicinal Chemistry. 26:1638-1642
Members of a series of basic amide and ester derivatives of 2-substituted pyrido[2,1-b]quinazoline-8-carboxylic acids were prepared and evaluated for their ability to prevent slow-reacting substance of anaphylaxis (SRS-A) induced contractions of guin
Publikováno v:
Helvetica Chimica Acta. 63:832-840
The 5-amino-3-arylamino-1,2,4-oxadiazoles 2 are conveniently prepared by oxidative cyclization of the arylamidinoureas 10. The process is also capable of producing a variety of the 5-substituted-amino analogs 32 when the appropriately substituted gua
Publikováno v:
Journal of Heterocyclic Chemistry. 16:333-337
The condensation of various halomethyl heterocycles with the potassium salt of the alanine derivative 3, followed by hydrolysis, gave a series of novel 3-heterocyclic-2-methylalanines.
Publikováno v:
Journal of Medicinal Chemistry. 23:1387-1392
Structure-activity studies were carried out on a series of antihypertensive 1-(2-aminoethyl)-3-(substituted phenyl)thioureas. From this class of compounds, the 2,6-dichlorophenyl analogue 2 was found to have potent oral antihypertensive activity in t
Publikováno v:
Helvetica Chimica Acta. 63:841-859
Publikováno v:
Tetrahedron Letters. 11:4121-4124
Publikováno v:
The Journal of Organic Chemistry. 38:373-377
Publikováno v:
Chemischer Informationsdienst. 15
Members of a series of basic amide and ester derivatives of 2-substituted pyrido[2,1-b]quinazoline-8-carboxylic acids were prepared and evaluated for their ability to prevent slow-reacting substance of anaphylaxis (SRS-A) induced contractions of guin
Publikováno v:
Chemischer Informationsdienst. 11
Autor:
Margaret O'Donnell, Jefferson Wright Tilley, A. F. Welton, L. D. Tobias, Joan M. Lind, Paul Levitan, Herman J. Crowley
Publikováno v:
Journal of medicinal chemistry. 30(1)
A series of N-(heterocyclic alkyl)pyrido[2,1-b]quinazoline-8-carboxamides were evaluated for their ability to antagonize slow-reacting substance of anaphylaxis (SRS-A) induced contractions of guinea pig ilea and to inhibit thromboxane synthase in vit