Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Paul Leff"'
Autor:
G S Forkuo, Paul Leff, Daniel Valdez, Brian J. Knoll, Richard A. Bond, Vaidehi J. Thanawala, Sergio Parra, Radhika Joshi, Michel Bouvier
Publikováno v:
British Journal of Pharmacology. 172:4833-4846
Background and purpose Our previous studies have shown the β2 -adrenoceptor and its endogenous ligand, adrenaline, are required for development of the asthma phenotype in murine asthma models. Chronic administration of some, but not other, β-blocke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9070faf31ed1e675b388182841e47d44
https://doi.org/10.1111/bph.13253
https://doi.org/10.1111/bph.13253
Autor:
Wayne Stallaert, Michel Bouvier, Vaidehi J. Thanawala, Richard A. Bond, Paul Leff, Gloria S. Forkuo
Publikováno v:
Current Opinion in Pharmacology. 16:50-57
β-blockers are used for a wide range of diseases from hypertension to glaucoma. In some diseases/conditions all β-blockers are effective, while in others only certain subgroups are therapeutically beneficial. The best-documented example for only a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::125a6fa1678de0bd0764185d5471fbe5
https://doi.org/10.1016/j.coph.2014.03.002
https://doi.org/10.1016/j.coph.2014.03.002
Publikováno v:
British journal of pharmacology. 173(1)
This article is a Commentary on Thanawala VJ, Valdez DJ, Joshi R, Forkuo GS, Parra S, Knoll BJ, Bouvier M, Leff P and Bond RA (2015). Beta‐blockers have differential effects on the murine asthma phenotype. Br J Pharmacol 172: 4833–4846. doi: 10.1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5e71a09c87e2e97f74f1b067734f9e4
https://pubmed.ncbi.nlm.nih.gov/26687673
https://pubmed.ncbi.nlm.nih.gov/26687673
Autor:
Peter F. Knowles, Paul Leff, William G. Bardsley, Kapil D. S. Yadav, Roy D. Waight, I D Kelly
Publikováno v:
European Journal of Biochemistry. 114:133-138
Steady-state kinetic studies on the enzyme benzylamine oxidase from pig plasma are described. Eadie-Hofstee plots with benzylamine as the varying substrate are non-linear; examination of this data indicates that the observed effects are probably due
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15ebc47360999f2a12a554f0f3b2bd54
https://doi.org/10.1111/j.1432-1033.1981.tb06183.x
https://doi.org/10.1111/j.1432-1033.1981.tb06183.x
Autor:
Joseph Goldfarb, Kelly A. Berg, Paul Leff, Saul Maayani, Clare Scaramellini, William P. Clarke
Publikováno v:
Molecular Pharmacology. 54:94-104
There are many examples of a single receptor coupling directly to more than one cellular signal transduction pathway. Although traditional receptor theory allows for activation of multiple cellular effectors by agonists, it predicts that the relative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f687a1309482c3960affcfb706c1ed1d
https://doi.org/10.1124/mol.54.1.94
https://doi.org/10.1124/mol.54.1.94
Autor:
Richard A. Bond, Gloria S. Forkuo, Brian J. Knoll, Paul Leff, Nour A. Al-Sawalha, Vaidehi J. Thanawala
Publikováno v:
The FASEB Journal. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9cef74f35755c3d22dfb505fec5bee6
https://doi.org/10.1096/fasebj.27.1_supplement.1107.5
https://doi.org/10.1096/fasebj.27.1_supplement.1107.5
Autor:
Clare, Scaramellini, Paul, Leff
Publikováno v:
Methods in enzymology. 343
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1d32eb1d4924f9165a95e4da36f825a7
https://pubmed.ncbi.nlm.nih.gov/11665565
https://pubmed.ncbi.nlm.nih.gov/11665565
Autor:
Paul Leff
Publikováno v:
Receptor-Based Drug Design ISBN: 9780429121326
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0486371b53022764e2225bb69ac5830
https://doi.org/10.1201/9781420001136-38
https://doi.org/10.1201/9781420001136-38
Autor:
Paul Leff
Publikováno v:
Receptor-Based Drug Design ISBN: 9780429121326
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e0d1b81af29f386ce65a9117527cfaa
https://doi.org/10.1201/9781420001136-4
https://doi.org/10.1201/9781420001136-4
Autor:
Paul Leff
Introduction, James Black Principles and Measurement of Drug-Receptor Interactions The Characterization and Classification of Receptors, Patrick P. A. Humphrey Functional Methods for Quantifying Agonists and Antagonists, Iain G. Dougall Quantificatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90a72992735895377b81e53d855bd530
https://doi.org/10.1201/9781420001136
https://doi.org/10.1201/9781420001136