Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Paul Labrousse"'
Autor:
Paul Labrousse, Daniel Stetson, James Hadfield, Chris Abbosh, Ahmet Zehir, Carl Barrett, Brian Dougherty, Darren Hodgson
Publikováno v:
Cancer Research. 83:LB293-LB293
The non-invasive detection of circulating tumor DNA (ctDNA) from plasma has been shown to have clinical value for detection of minimal residual disease (MRD), identification of emerging resistance to treatment, and predicting treatment response. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afe6965defdd5ae334f4d3cb7e8e1dd6
https://doi.org/10.1158/1538-7445.am2023-lb293
https://doi.org/10.1158/1538-7445.am2023-lb293
Autor:
Veerendra Munugalavadla, Gary de Jesus, Aleksandra Markovets, Qinwen Liu, Oliver Venn, Rafael White, Giulia Fabbri, Paul Labrousse, Dan Stetson, Brian Dougherty, Darren Hodgson, Jill Walker, Anas Younes, Daniel Auclair
Publikováno v:
Cancer Research. 83:3369-3369
Introduction: Minimal or measurable residual disease (MRD) is an emerging independent predictor of progression-free and overall survival in several hematologic diseases. Despite many different methods used in clinical trials, few assays have clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7790fed47f9602e932cbf7c70ba5a8d9
https://doi.org/10.1158/1538-7445.am2023-3369
https://doi.org/10.1158/1538-7445.am2023-3369
Autor:
Andrew Bloecher, Brian Dougherty, Deborah Lawson, Daniel Stetson, Courtney L. Andersen, Amanda L. Christie, Justine Roderick, Jacob Gordon, Corinne Reimer, Denise Hughes, Brandon Willis, Kimberly Maratea, Paul Labrousse
Publikováno v:
Cancer Research. 81:2957-2957
We have established a novel assay to assess circulating tumor DNA (ctDNA) in mice engrafted with disseminated cell line and patient-derived xenografts (PDX) of hematologic malignancies. Disseminated models recapitulate many features of human disease,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::347485720e43a8735b220af1f9013eca
https://doi.org/10.1158/1538-7445.am2021-2957
https://doi.org/10.1158/1538-7445.am2021-2957
Autor:
Robert J. Pomponio, Joan Keutzer, Paul Labrousse, Wuh-Liang Hwu, Ni-Chung Lee, Thomas Scholl, Yin-Hsiu Chien, Viatcheslav R. Akmaev
Publikováno v:
Molecular Genetics and Metabolism. 99:379-383
Pompe disease is an autosomal recessive lysosomal storage disorder (LSD) caused by deficiency of lysosomal acid alpha-glucosidase (GAA) activity. This is the first LSD in which newborn screening has been shown to improve clinical outcomes. Newborn sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d09a33cab5ac0cd4619bd0c220e35efe
https://doi.org/10.1016/j.ymgme.2009.12.014
https://doi.org/10.1016/j.ymgme.2009.12.014
Autor:
Kerry Flynn, Paul Labrousse, Andrew M. Walker, Christopher Sears, Bernice A Allitto, Colin Donohoe, Elizabeth M. Rohlfs, Elaine A Sugarman, Leonid Boguslavskiy, Brant C. Hendrickson, Thomas Scholl, Viatcheslav R. Akmaev
Publikováno v:
Journal of Medical Genetics
Background: Spinal muscular atrophy (SMA) is the most common inherited lethal disease of children. Various genetic deletions involving the bi-allelic loss of SMN1 exon 7 are reported to account for 94% of affected individuals. Published literature pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4243e8e043d9317c943aba9ebb0e8587
https://doi.org/10.1136/jmg.2009.066969
https://doi.org/10.1136/jmg.2009.066969
Autor:
Weihua Liu, Selby Weeks, Zhenyu Yan, Jin Li, Jennifer Biroschak, Peng Fang, Paul Labrousse, Chad Galderisi, Jennifer Wright, Cindy Spittle
Publikováno v:
Cancer Research. 76:1397-1397
Introduction: The Oncomine™ Focus Assay (OFA) is aimed to simultaneously detect and report hotspot mutations, Copy Number Variants (CNVs) and gene fusions in 52 oncogenes clinically relevant to solid tumors. With minimal DNA/RNA input, OFA employs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00a470f038ecdc6c7c6d9c25cdb5d079
https://doi.org/10.1158/1538-7445.am2016-1397
https://doi.org/10.1158/1538-7445.am2016-1397
Autor:
Zhenyu Yan, Peng Fang, Jennifer Biroschak, Weihua Liu, Jin Li, Chad Galderisi, Cindy Spittle, Paul Labrousse
Publikováno v:
Molecular Cancer Therapeutics. 14:A29-A29
Introduction: Analysis of ctDNA has potential applications in targeted therapy selection and disease monitoring in the clinical management of colorectal cancer. Here we use an amplicon based target enrichment method, AmpliSeq v2 (CHP2), to study a se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb260e474fa4d36975c9ca8d612b16d1
https://doi.org/10.1158/1535-7163.targ-15-a29
https://doi.org/10.1158/1535-7163.targ-15-a29
Autor:
Jennifer Biroschak, Zhenyu Yan, Li Jin, Jennifer Wright, Paul Labrousse, Chad Galderisi, Weihua Liu, Cindy Spittle, Peng Fang
Publikováno v:
Cancer Research. 75:4261-4261
Introduction: The Oncomine® Cancer Panel (OCP) is designed to simultaneously detect and report hotspot mutations, Copy Number Variants (CNVs) and gene fusions in 143 genes with minimal DNA/RNA sample input. The OCP utilizes the AmpliSeq™ library p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81c3374ed0c2ca5e93a6a167d58f4101
https://doi.org/10.1158/1538-7445.am2015-4261
https://doi.org/10.1158/1538-7445.am2015-4261
Autor:
Lidia Epp, Lawrence M. Silverman, Victoria M. Pratt, Jean Amos Wilson, C. Sue Richards, Kasinathan Muralidharan, Scott J. Bridgeman, W. Edward Highsmith, Ebony M. Courtney, Amit Phansalkar, Jeanne C. Beck, John P. Jakupciak, Leonard M. Holtegaard, Monique A. Johnson, Paul Labrousse, Nick L. Hjelm, Elaine Lyon, Andrea Ferreira-Gonzalez, Thomas W. Prior, Joanna Wiszniewska, Kristy L. Richie, Elizabeth M. Rohlfs, Karen A. Siegrist, Lisa V. Kalman, Tina Sellers, Benjamin B. Roa, Mohamed Jama, Stephanie L. Sherman
Publikováno v:
The Journal of molecular diagnostics : JMD. 10(1)
Fragile X syndrome, which is caused by expansion of a (CGG)(n) repeat in the FMR1 gene, occurs in approximately 1:3500 males and causes mental retardation/behavioral problems. Smaller (CGG)(n) repeat expansions in FMR1, premutations, are associated w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8ce9c28264e48ac26ee526c2808ea04
https://pubmed.ncbi.nlm.nih.gov/18165276
https://pubmed.ncbi.nlm.nih.gov/18165276
Autor:
Peng Fang, Jennifer Biroschak, Paul Labrousse, Weihua Liu, Chad Galderisi, Zhenyu Yan, Cindy Spittle, Jin Li, Jennifer Wright
Publikováno v:
Journal of Thoracic Oncology. (2):S21-S22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00419f306b352f6d3bfec3e3ba38b8b6