Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Paul L. Schiff"'
Autor:
Josep Saurí, Edward C. Sherer, Gary E. Martin, Wolfgang Bermel, Alexei V. Buevich, Teodor Parella, Paul L. Schiff, Leo A. Joyce, Maged H. M. Sharaf, R. Thomas Williamson
Publikováno v:
Angewandte Chemie International Edition. 54:10160-10164
Cryptospirolepine is the most structurally complex alkaloid discovered and characterized thus far from any Cryptolepis specie. Characterization of several degradants of the original, sealed NMR sample a decade after the initial report called the vali
Autor:
Bruce A. Stiemsma, Antony J. Williams, Eduard R. Martirosian, Thomas J. Thamann, Sergey G. Molodtsov, Gary E. Martin, David J. Russell, Brian D. Kaluzny, Paul L. Schiff, Chad E. Hadden, Ronald C. Crouch, Kirill A. Blinov, Mikhail E. Elyashberg, Jane E. Guido, Wayne K. Duholke
Publikováno v:
Journal of Heterocyclic Chemistry. 39:1241-1250
Identification of degradants of pharmaceuticals is a necessary challenge of the drug development process following the subjection of candidate molecules to a variety of physico-chemical stresses. It would be desirable to be able to conduct such studi
Publikováno v:
Journal of Herbal Pharmacotherapy. 2:1-10
Autor:
Gary E. Martin, Fu-Tyan Lin, Paul L. Schiff, Tawfeq A. Al-Howiriny, Cong-Yuan Gao, Chad E. Hadden, Michael A. Zemaitis
Publikováno v:
Journal of Natural Products. 64:823-826
A direct comparison of the spectral data for synthetic 2-methyl-6,7-dimethoxy-3'-methoxy-4'-hydroxyoxobenzylisoquinoline iodide (1) and its positional isomer 2-methyl-6,7-dimethoxy-3'-hydroxy-4'-methoxyoxobenzylisoquinoline iodide (2) with the data o
Autor:
V. Srini Srinivasan, Paul L. Schiff
Publikováno v:
Journal of Herbal Pharmacotherapy. 1:1-29
The USP Sub com mit tee on Natural Prod ucts was formed in the summer of 1995. Its principal charge was to explore the feasibility and advisability of establishing standards (monographs) for botanical dietary suppiements. This paper describes the wor
Publikováno v:
Magnetic Resonance in Chemistry. 37:529-537
Autor:
Paul L. Schiff, Wayne K. Duholke, Russell H. Robins, Chad E. Hadden, Jane E. Guido, Gary E. Martin, Maged H. M. Sharaf
Publikováno v:
Journal of Heterocyclic Chemistry. 36:525-531
The nmr analysis of a mixture of cryptolepinone and it's 5(N)-oxide in a 1.5:1 ratio is discussed. The differentiation of the resonances of the two similar compounds, and elucidation of the unknown 5(N)-oxide relied primarily on IDR-GHSQC-TOCSY data
Autor:
Maged H. M. Sharaf, Albert N. Tackie, James R. Blinn, Gary E. Martin, Paul L. Schiff, Chad E. Hadden
Publikováno v:
Magnetic Resonance in Chemistry. 37:1-6
Direct and long-range 1H–15N correlations for cryptolepinone and its N5-oxide as a mixture in DMSO-d6 were determined using a combination of 1H–15N GHSQC and GHMBC experiments. The 15N chemical shifts of cryptolepinone in the mixture were compara
Publikováno v:
Journal of Heterocyclic Chemistry. 35:1365-1369
An indolo[3,2-b]quinoline alkaloid bearing an N-methyl substituent at N5, and an oxygen moiety at the 11-position has been variously described as both cryptolepinone and 11-hydroxycryptolepine by independent research groups. The structure of this alk
Autor:
Ronald C. Crouch, Gary E. Martin, Charles H. Phoebe, Doug Minick, Paul L. Schiff, Maged H. M. Sharaf, Robert L. Johnson, Albert N. Tackie, C. Webster Andrews
Publikováno v:
Journal of Heterocyclic Chemistry. 33:789-797
The isolation and structure determination of cryptomisrine, a novel indolo[3,2-b]quinoline dimeric alkaloid obtained from extracts of the roots of the Ghanaian medicinal plant Cryptolepis sanguinolenta is reported. The structure determination was mad