Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Paul L. Greer"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The mammalian olfactory system detects and discriminates between millions of odorants to elicit appropriate behavioral responses. While much has been learned about how olfactory sensory neurons detect odorants and signal their presence, how
Externí odkaz:
https://doaj.org/article/ce9f4cc2e7f342b29aa501742baf4add
Autor:
Namgyu Lee, Sung Jin Park, Mike Lange, Tenzin Tseyang, Mihir B. Doshi, Tae Yong Kim, Yoseb Song, Dong In Kim, Paul L. Greer, James A. Olzmann, Jessica B. Spinelli, Dohoon Kim
The canonical biological function of selenium is in the production of selenocysteine residues of selenoproteins, and this forms the basis for its role as an essential antioxidant and cytoprotective micronutrient. Here, we demonstrate that selenium, v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::238be02ad131d1d3798fc4e04a2721d0
https://doi.org/10.1101/2023.04.13.535674
https://doi.org/10.1101/2023.04.13.535674
Autor:
I-Hao Wang, Evan Murray, Greg Andrews, Hao-Ching Jiang, Sung Jin Park, Elisa Donnard, Violeta Durán-Laforet, Daniel M. Bear, Travis E. Faust, Manuel Garber, Christina E. Baer, Dorothy P. Schafer, Zhiping Weng, Fei Chen, Evan Z. Macosko, Paul L. Greer
Publikováno v:
Nat Neurosci
The olfactory system’s ability to detect and discriminate between the vast array of chemicals present in the environment is critical for an animal’s survival. In mammals, the first step of this odor processing is executed by olfactory sensory neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e372fecd09e95875510bb7d6168bae1
https://europepmc.org/articles/PMC9281876/
https://europepmc.org/articles/PMC9281876/
Autor:
Meghan E. Spears, Namgyu Lee, Sunyoung Hwang, Sung Jin Park, Anne E. Carlisle, Rui Li, Mihir B. Doshi, Aaron M. Armando, Jenny Gao, Karl Simin, Lihua Julie Zhu, Paul L. Greer, Oswald Quehenberger, Eduardo M. Torres, Dohoon Kim
Publikováno v:
Cell reports. 40(13)
Sphingolipids play important signaling and structural roles in cells. Here, we find that during de novo sphingolipid biosynthesis, a toxic metabolite is formed with critical implications for cancer cell survival. The enzyme catalyzing the first step
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e659588f61e0c2f12e8cceba924d2be
https://pubmed.ncbi.nlm.nih.gov/36170811
https://pubmed.ncbi.nlm.nih.gov/36170811
Autor:
Eric L. Greer, George Sabin, Benjamin A. Garcia, Simon Yuan Wang, Henry L. Bushnell, Paul L. Greer, Colette Fritsche, Ken Takashima, I-Hao Wang, Elizabeth A. Pollina, Lindsay K. Pino
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-30 (2021)
Genome Biology
Genome Biology
Background The evolution of multicellularity is a critical event that remains incompletely understood. We use the social amoeba, Dictyostelium discoideum, one of the rare organisms that readily transits back and forth between both unicellular and mul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1491883bb38dac56a25eb8d94f92201d
https://doi.org/10.1186/s13059-021-02360-9
https://doi.org/10.1186/s13059-021-02360-9
Autor:
George Sabin, I-Hao Wang, Simon Yuan Wang, Eric L. Greer, Ken Takashima, Henry L. Bushnell, Paul L. Greer, Colette Fritsche, Elizabeth A. Pollina
The evolution of multicellularity is a critical event that remains incompletely understood. We use the social amoeba,Dictyostelium discoideum,one of the rare organisms that exists in both unicellular and multicellular stages, to examine the role of e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a972b6470b939412b3460284c2a69b2
https://doi.org/10.1101/2020.09.03.282152
https://doi.org/10.1101/2020.09.03.282152
Autor:
Miles Smith, Daniel Youkana, Namgyu Lee, Asia N. Matthew-Onabanjo, Dohoon Kim, Sung Jin Park, Paul L. Greer, Karl Simin, Mihir B. Doshi, Alexander B. Joseph, Austin Peppers, Meghan E. Spears, Lihua Julie Zhu, Leslie M. Shaw, Rui Li, Anne E. Carlisle
Publikováno v:
Nature metabolism
The micronutrient selenium is incorporated via the selenocysteine biosynthesis pathway into the rare amino acid selenocysteine, which is required in selenoproteins such as glutathione peroxidases and thioredoxin reductases1,2. Here, we show that sele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d348b82182620dcf9baf7e9c6799fb
https://pubmed.ncbi.nlm.nih.gov/32694795
https://pubmed.ncbi.nlm.nih.gov/32694795
Autor:
Melanie A. Samuel, Paul L. Greer
Publikováno v:
Neuron. 103(6)
Starting your own academic lab is a wonderful opportunity to impact science through research and trainee mentoring. In this article, we share some thoughts and resources for this undertaking in the hope that they may enhance the experience of others.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9da87f6223eefb4db647f605df8b38ca
https://pubmed.ncbi.nlm.nih.gov/31557459
https://pubmed.ncbi.nlm.nih.gov/31557459
Autor:
Sandeep Robert Datta, Adriana Eisner, Laura Persson, Paul L. Greer, Rosalind A. Segal, Maria F. Pazyra-Murphy, Rochelle M. Witt, Meghan M. Galligan
Publikováno v:
Developmental Neurobiology. 74:1255-1267
The olfactory system relies on precise circuitry connecting olfactory sensory neurons (OSNs) and appropriate relay and processing neurons of the olfactory bulb (OB). In mammals, the exact correspon- dence between specific olfactory receptor types and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e248580c6fabbeef6e7297e43743a8f2
https://doi.org/10.1002/dneu.22202
https://doi.org/10.1002/dneu.22202
Autor:
Tatsuya Tsukahara, Stan L. Pashkovski, Francis Kei Masuda, Jean-Marc Lassance, Hopi E. Hoekstra, Alexandra C. Nowlan, Rory Kirchner, Daniel M. Bear, Maria Lissitsyna Bloom, Sandeep Robert Datta, Paul L. Greer
Publikováno v:
Cell. 165(7)
Summary Odor perception in mammals is mediated by parallel sensory pathways that convey distinct information about the olfactory world. Multiple olfactory subsystems express characteristic seven-transmembrane G-protein-coupled receptors (GPCRs) in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbe8c5e873338d2503e14fc15bd2450e
https://pubmed.ncbi.nlm.nih.gov/27315472
https://pubmed.ncbi.nlm.nih.gov/27315472