Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Paul L McNeil"'
Publikováno v:
PLoS ONE, Vol 2, Iss 8, p e687 (2007)
BACKGROUND: Ingestion of the lectins present in certain improperly cooked vegetables can result in acute GI tract distress, but the mechanism of toxicity is unknown. In vivo, gut epithelial cells are constantly exposed to mechanical and other stresse
Externí odkaz:
https://doaj.org/article/8061df6d13e84a5399a5950015fc1407
Autor:
Hsueh-Fen Juan, Chiung-Nien Chen, Jin-Town Wang, Meng-Chuan Wu, Paul L. McNeil, Satoshi Ogihara, Hsuan-Cheng Huang, Li-Ling Lin
Publikováno v:
International Journal of Molecular Sciences, Vol 13, Iss 8, Pp 10176-10192 (2012)
Helicobacter pylori (H. pylori), the human stomach pathogen, lives on the inner surface of the stomach and causes chronic gastritis, peptic ulcer, and gastric cancer. Plasma membrane repair response is a matter of life and death for human cells again
Externí odkaz:
https://doaj.org/article/1e6483ba61554b50ab51e8f189af8521
Autor:
Rachel L. Roberts, Paul L. McNeil, Marlian Montesinos Cartagena, Mackenzie L. Hagan, Carlos M. Isales, Meghan E. McGee-Lawrence, Mark W. Hamrick, Kanglun Yu, Brooke N Vinson, Liyun Wang, Jiali Zhu, Maribeth H. Johnson
Publikováno v:
Aging Cell
Transient plasma membrane disruptions (PMD) occur in osteocytes with in vitro and in vivo loading, initiating mechanotransduction. The goal here was to determine whether osteocyte PMD formation or repair is affected by aging. Osteocytes from old (24
Autor:
Timothy Kurtz, Anna K. McNeil, Ronald B. Pegg, Marcus Conrad, Taylor C. Lee, M. Labazi, Paul L. McNeil, José Pedro Friedmann Angeli
Publikováno v:
Free Radical Biology and Medicine. 84:246-253
Vitamin E (VE) deficiency results in pronounced muscle weakness and atrophy but the cell biological mechanism of the pathology is unknown. We previously showed that VE supplementation promotes membrane repair in cultured cells and that oxidants poten
Autor:
David P. Sellman, Mackenzie L. Hagan, Mark W. Hamrick, Meghan E. McGee-Lawrence, Kayce T. Vanpelt, Anoosh Bahraini, Peyton L. Marshall, Anna K. McNeil, Kanglun Yu, Paul L. McNeil, Ahmed Elsherbini
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 36(2)
Osteocytes sense loading in bone, but their mechanosensation mechanisms remain poorly understood. Plasma membrane disruptions (PMD) develop with loading under physiological conditions in many cell types (e.g., myocytes, endothelial cells). These PMD
Autor:
Quincy Zhong, Ding Xie, Xiaofeng Zhong, Wendy B. Bollag, Paul L. McNeil, Senthil Nathan Arun, Amber C. Howard
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 3, Pp 581-591 (2013)
Plasma membrane disruptions occur in mechanically active tissues such as the epidermis and can lead to cell death if the damage remains unrepaired. Repair occurs through fusion of vesicle patches to the damaged membrane region. The enzyme phospholipa
Publikováno v:
Environmental pollution (Barking, Essex : 1987). 218
The development of the eye in vertebrates is dependent upon glucocorticoid signalling, however, specific components of the eye are sensitive to synthetic glucocorticoids. The presence of synthetic glucocorticoids within the aquatic environment may th
Publikováno v:
Environmental sciencetechnology. 50(10)
The presence of synthetic glucocorticoids within the aquatic environment has been highlighted as a potential environmental concern as they may mimic the role of endogenous glucocorticoids during vertebrate ontogeny. Prednisolone is a commonly prescri
Publikováno v:
Frandsen, S K, McNeil, A K, Novak, I, McNeil, P L & Gehl, J 2016, ' Difference in membrane repair capacity between cancer cell lines and a normal cell line ', Journal of Membrane Biology, vol. 249, no. 4, pp. 569-576 . https://doi.org/10.1007/s00232-016-9910-5
The Journal of Membrane Biology
The Journal of Membrane Biology
Electroporation-based treatments and other therapies that permeabilize the plasma membrane have been shown to be more devastating to malignant cells than to normal cells. In this study, we asked if a difference in repair capacity could explain this o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b58fb97a6cfc44fcc0eec3f35db83346
https://curis.ku.dk/ws/files/164452725/Difference_in_membrane_repair_capacity_between_cancer_cell_lines_and_a_normal_cell_line.pdf
https://curis.ku.dk/ws/files/164452725/Difference_in_membrane_repair_capacity_between_cancer_cell_lines_and_a_normal_cell_line.pdf
Publikováno v:
Diabetes. 60:3034-3043
OBJECTIVE Skeletal muscle myopathy is a common diabetes complication. One possible cause of myopathy is myocyte failure to repair contraction-generated plasma membrane injuries. Here, we test the hypothesis that diabetes induces a repair defect in sk