Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Paul L Bollyky"'
Autor:
Koshika Yadava, Carlos Obed Medina, Heather Ishak, Irina Gurevich, Hedwich Kuipers, Elya Ali Shamskhou, Ievgen O Koliesnik, James J Moon, Casey Weaver, Kari Christine Nadeau, Paul L Bollyky
Publikováno v:
eLife, Vol 8 (2019)
IL-10-producing Tr1 cells promote tolerance but their contributions to tolerogenic memory are unclear. Using 10BiT mice that carry a Foxp3-eGFP reporter and stably express CD90.1 following IL-10 production, we characterized the spatiotemporal dynamic
Externí odkaz:
https://doaj.org/article/8b7fcf2e0605494491f31295417f4c06
Autor:
Swathi Balaji, Alice King, Emily Marsh, Maria LeSaint, Sukanta S Bhattacharya, Nathaniel Han, Yashu Dhamija, Rajeev Ranjan, Louis D Le, Paul L Bollyky, Timothy M Crombleholme, Sundeep G Keswani
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0124302 (2015)
Mid-gestation fetal cutaneous wounds heal scarlessly and this has been attributed in part to abundant hyaluronan (HA) in the extracellular matrix (ECM) and a unique fibroblast phenotype. We recently reported a novel role for interleukin 10 (IL-10) as
Externí odkaz:
https://doaj.org/article/3e52d1d4d8594f649ff928cf86a3e979
Autor:
Silvia Würstle, Alina Lee, Kaitlyn E. Kortright, Franziska Winzig, William An, Gail L. Stanley, Govindarajan Rajagopalan, Zach Harris, Ying Sun, Buqu Hu, Michael Blazanin, Maryam Hajfathalian, Paul L. Bollyky, Paul E. Turner, Jonathan L. Koff, Benjamin K. Chan
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Bacteriophage therapy is one potential strategy to treat antimicrobial resistant or persistent bacterial infections, and the year 2021 marked the centennial of Felix d’Hérelle’s first publication on the clinical applications of phages.
Externí odkaz:
https://doaj.org/article/41cdfd5460a14d8d9cd220874c8a6c29
Autor:
Hunter A. Martinez, Ievgen Koliesnik, Gernot Kaber, Jacqueline K. Reid, Nadine Nagy, Graham Barlow, Ben A. Falk, Carlos O. Medina, Aviv Hargil, Svenja Zihsler, Israel Vlodavsky, Jin-Ping Li, Magdiel Pérez-Cruz, Sai-Wen Tang, Everett H. Meyer, Lucile E. Wrenshall, James D. Lord, K. Christopher Garcia, Theo D. Palmer, Lawrence Steinman, Gerald T. Nepom, Thomas N. Wight, Paul L. Bollyky, Hedwich F. Kuipers
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Although FOXP3+ regulatory T cells (Treg) depend on IL-2 produced by other cells for their survival and function, the levels of IL-2 in inflamed tissue are low, making it unclear how Treg access this critical resource. Here, we show that Tre
Externí odkaz:
https://doaj.org/article/378775d4b0fd41108905367cda2de0de
Autor:
Nadine Nagy, Kathryn S. Czepiel, Gernot Kaber, Darko Stefanovski, Aviv Hargil, Nina Pennetzdorfer, Robert Targ, Saranya C. Reghupaty, Thomas N. Wight, Robert B. Vernon, Rebecca L. Hull-Meichle, Payton Marshall, Carlos O. Medina, Hunter Martinez, Anissa Kalinowski, Rudolph D. Paladini, Stavros Garantziotis, Joshua W. Knowles, Paul L. Bollyky
Publikováno v:
Cells, Vol 13, Iss 20, p 1727 (2024)
Given that the extracellular matrix polymer hyaluronan (HA) has been implicated in longevity, we asked whether 4-methylumbelliferone (4-MU), an inhibitor of HA synthesis, impacts lifespan in mice. We designed a prospective study of long-term administ
Externí odkaz:
https://doaj.org/article/da7d8866843c4dd994d1c93481a81662
Autor:
Xinhui Ge, John A Gebe, Paul L Bollyky, Eddie A James, Junbao Yang, Lawrence J Stern, William W Kwok
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11355 (2010)
Peptide:MHC cellular microarrays have been proposed to simultaneously characterize multiple Ag-specific populations of T cells. The practice of studying immune responses to complicated pathogens with this tool demands extensive knowledge of T cell ep
Externí odkaz:
https://doaj.org/article/bb68f6c404924441bdf2b1b8da510837
Autor:
Paul L Bollyky, Jeffrey B Bice, Ian R Sweet, Ben A Falk, John A Gebe, April E Clark, Vivian H Gersuk, Alan Aderem, Thomas R Hawn, Gerald T Nepom
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5063 (2009)
Commensal flora and pathogenic microbes influence the incidence of diabetes in animal models yet little is known about the mechanistic basis of these interactions. We hypothesized that Myd88, an adaptor molecule in the Toll-like-receptor (TLR) pathwa
Externí odkaz:
https://doaj.org/article/9987147706c64cf880f4caff02e0835c
Autor:
Maryam Hajfathalian, Christiaan R. de Vries, Jessica C. Hsu, Ahmad Amirshaghaghi, Yuxi C. Dong, Zhi Ren, Yuan Liu, Yue Huang, Yong Li, Simon A.B. Knight, Pallavi Jonnalagadda, Aimen Zlitni, Elizabeth A. Grice, Paul L. Bollyky, Hyun Koo, David P. Cormode
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 21 (2023)
Biofilms are structured communities of microbial cells embedded in a self-produced matrix of extracellular polymeric substances. Biofilms are associated with many health issues in humans, including chronic wound infections and tooth decay. Current an
Externí odkaz:
https://doaj.org/article/b99ed845707e4ebba806d4d215686db5
Autor:
Nina Pennetzdorfer, Medeea C. Popescu, Naomi L. Haddock, Fannie Dupuy, Gernot Kaber, Aviv Hargil, Patrik K. Johansson, Annika Enejder, Paul L. Bollyky
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Pseudomonas aeruginosa is a major human pathogen, particularly effective at colonizing the airways of patients with cystic fibrosis. Bacteriophages are highly abundant at infection sites, but their impact on mammalian immunity remains unclear. We pre
Externí odkaz:
https://doaj.org/article/6c40b20b46ef483f99cd6caad4fd8eca
Autor:
Anping Xia, Anthony Thai, Zhixin Cao, Xiaohua Chen, Jing Chen, Brian Bacacao, Laurent A. Bekale, Viktoria Schiel, Paul L. Bollyky, Peter L. Santa Maria
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-15 (2022)
Abstract Background Chronic suppurative otitis media (CSOM) is the most common cause of permanent hearing loss in children in the developing world. A large component of the permanent hearing loss is sensory in nature and our understanding of the mech
Externí odkaz:
https://doaj.org/article/958afb0cf6b0467980759237b07e4366