Zobrazeno 1 - 10
of 175
pro vyhledávání: '"Paul Kwong Hang, Tam"'
Autor:
Yongqin Ye, Hor Yee Kimberley Tong, Wai Hong Chong, Zhiqian Li, Paul Kwong Hang Tam, Daniel T. Baptista-Hon, Olivia Monteiro
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Antibiotics are indispensable to infection management. However, use of antibiotics can cause gut microbiota dysbiosis, which has been linked to cognitive impairment by disrupting communication between the gut microbiota and the brain. We con
Externí odkaz:
https://doaj.org/article/c16be70debd0462cae6265a9334753b6
Publikováno v:
Cells, Vol 13, Iss 23, p 1997 (2024)
The aim of this review is to explore the potential of new regenerative medicine approaches in the treatment of cholestatic liver fibrosis. Cholestatic liver diseases, such as primary biliary cholangitis (PBC), primary sclerosing cholangitis (PSC), an
Externí odkaz:
https://doaj.org/article/3b09a5f8bd564934b4dd980ce67a1eab
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
Genetic mutations are critical factors leading to congenital surgical diseases and can be identified through genomic analysis. Early and accurate identification of genetic mutations underlying these conditions is vital for clinical diagnosis and effe
Externí odkaz:
https://doaj.org/article/bc52d55116d34ee7bee9ea3621c26cd1
Autor:
Vincent Chi-Hang Lui, Kenrie Pui-Yan Hui, Rosanna Ottakandathil Babu, Haibing Yue, Patrick Ho-Yu Chung, Paul Kwong-Hang Tam, Michael Chi-Wai Chan, Kenneth Kak-Yuen Wong
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Although the main route of infection for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the respiratory tract, liver injury is also commonly seen in many patients, as evidenced by deranged parenchymal liver enzymes. Furtherm
Externí odkaz:
https://doaj.org/article/1bab0293cb384c0ab4cb4c68c6c28511
Autor:
Jeffrey Fong Ting Chau, Mullin Ho Chung Yu, Martin Man Chun Chui, Cyrus Chun Wing Yeung, Aaron Wing Cheung Kwok, Xuehan Zhuang, Ryan Lee, Jasmine Lee Fong Fung, Mianne Lee, Christopher Chun Yu Mak, Nicole Ying Ting Ng, Claudia Ching Yan Chung, Marcus Chun Yin Chan, Mandy Ho Yin Tsang, Joshua Chun Ki Chan, Kelvin Yuen Kwong Chan, Anita Sik Yau Kan, Patrick Ho Yu Chung, Wanling Yang, So Lun Lee, Godfrey Chi Fung Chan, Paul Kwong Hang Tam, Yu Lung Lau, Kit San Yeung, Brian Hon Yin Chung, Clara Sze Man Tang
Publikováno v:
npj Genomic Medicine, Vol 7, Iss 1, Pp 1-9 (2022)
Abstract Traditional carrier screening has been utilized for the detection of carriers of genetic disorders. Since a comprehensive assessment of the carrier frequencies of recessive conditions in the Southern Chinese population is not yet available,
Externí odkaz:
https://doaj.org/article/a4439854ca474791ac85c6eeb89fbddb
Autor:
Patrick Ho-Yu Chung, Rosana Ottakandathil Babu, Zhongluan Wu, Kenneth Kak-Yuen Wong, Paul Kwong-Hang Tam, Vincent Chi-Hang Lui
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 2, Pp 644-653 (2022)
Background: We explored the feasibility of creating BA-like organoids by treating human liver organoids with Polyinosinic:Polycytidylic acid (Poly I:C). Methods: Organoids were developed from the liver parenchyma collected during Kasai portoenterosto
Externí odkaz:
https://doaj.org/article/5c1f686ffe4946fbb749b3fe90c426b3
Autor:
Yongqin Ye, Vincent Chi Hang Lui, Rosana Ottakandathil Babu, Zhongluan Wu, Weifang Wu, Patrick Ho Yu Chung, Kenneth Kak Yuen Wong, Bin Wang, Paul Kwong Hang Tam
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0283737 (2023)
BackgroundCholedochal cysts (CC) are congenital bile duct anomalies with 6-30% risk for developing bile duct cancer. However, the molecular mechanisms underlying cancer risk of CC are unknown. We sought to identify the gene expression changes underly
Externí odkaz:
https://doaj.org/article/93f32b147f7a4a30bf6043cba0da682c
Autor:
Hongyu Lyu, Yongqin Ye, Vincent Chi Hang Lui, Weifang Wu, Patrick Ho Yu Chung, Kenneth Kak Yuen Wong, Hung-Wing Li, Man Shing Wong, Paul Kwong Hang Tam, Bin Wang
Publikováno v:
Frontiers in Surgery, Vol 9 (2022)
BackgroundBiliary atresia (BA) is an infantile fibro-obstructive cholestatic disease with poor prognosis. An early diagnosis and timely Kasai portoenterostomy (KPE) improve clinical outcomes. Aggregation of amyloid-beta (Aβ) around hepatic bile duct
Externí odkaz:
https://doaj.org/article/413a2de983a3431faaa027097c20c71f
Autor:
Lin He, Dennis Kai Ming Ip, Greta Tam, Vincent Chi Hang Lui, Paul Kwong Hang Tam, Patrick Ho Yu Chung
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract To evaluate the accuracy of biomarkers for the early diagnosis of biliary atresia (BA) and prognostic stratification after Kasai portoenterostomy (KPE). We conducted a systematic review of PubMed, Web of Science, Embase, Scopus and OVID for
Externí odkaz:
https://doaj.org/article/a955149154d04b84b8c5ecae5beaf15d
Autor:
Patrick Ho Yu Chung, Edwin Kin Wai Chan, Fanny Yeung, Albert Chi Yan Chan, Jennifer Wai Cheung Mou, Kim Hung Lee, Judy Wing Suet Hung, Michael Wai Yip Leung, Paul Kwong Hang Tam, Kenneth Kak Yuen Wong
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract We present a 37 years’ experience in the management of biliary atresia (BA) and discuss long-term complications after Kasai portoenterostomy (KPE). A retrospective territory-wide study from 1980 to 2017 on 231 patients with open KPE from t
Externí odkaz:
https://doaj.org/article/cd43f546b5924971a20dca65ede4e12b