Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Paul Kippax"'
Publikováno v:
Journal of Pharmaceutical Sciences. 108:3515-3520
Particle size analysis in the pharmaceutical industry has long been a source of debate regarding how best to define measurement accuracy; the degree to which the result of a measurement or calculation conforms to the true value. Defining a “true”
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a9cd5b19c4b7edd4a0af5970e1a1c4b
https://doi.org/10.1016/j.xphs.2019.08.007
https://doi.org/10.1016/j.xphs.2019.08.007
Publikováno v:
Powder Technology. 250:75-83
Powder processing operations can give rise to tribo-electrification of particles. The resulting electrostatic force can cause segregation/agglomeration of particles as well as their adhesion to the walls of the processing equipment, adversely affecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9208a6f5524cb59cbd6f1175fa3d04d2
https://doi.org/10.1016/j.powtec.2013.10.006
https://doi.org/10.1016/j.powtec.2013.10.006
Publikováno v:
Powder Technology. 240:88-94
The relationship between bulk powder cohesion and ease of powder dispersion is of interest for many applications including particle characterisation and drug delivery from dry powder inhalers. Quasi-static bulk powder testing is used to evaluate powd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a3c63b80630298098154e525732054a
https://doi.org/10.1016/j.powtec.2012.07.003
https://doi.org/10.1016/j.powtec.2012.07.003
Autor:
Paul Kippax, David Alexander Vodden Morton, Ian Larson, Peter Stewart, Srinivas Ravindra Babu Behara
Publikováno v:
International Journal of Pharmaceutics. 421:72-81
The purpose of the current investigation is to understand the kinetics of de-agglomeration (k(d)) of micronised salbutamol sulphate (SS) and lactohale 300 (LH300) under varying air flow rates (30-180l min(-1)) from three dry powder inhaler devices (D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79309ea6b6825059134f4f901033c7f7
https://doi.org/10.1016/j.ijpharm.2011.09.024
https://doi.org/10.1016/j.ijpharm.2011.09.024
Autor:
Peter Stewart, Srinivas Ravindra Babu Behara, Ian Larson, Paul Kippax, David Alexander Vodden Morton
Publikováno v:
Chemical Engineering Science. 66:5284-5292
The purpose of this study was to understand the kinetics of emptying of micronised salbutamol sulphate (SS) and lactohale 300 (LH300) under varying air flow rates (30–180 L min −1 ) from three dry powder inhaler devices, Rotahaler ® (RH), Monodo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f025cbfa32bbce3824d73ff81d916e8
https://doi.org/10.1016/j.ces.2011.07.029
https://doi.org/10.1016/j.ces.2011.07.029
Autor:
Srinivas Ravindra Babu Behara, Paul Kippax, Ian Larson, Peter Stewart, David Alexander Vodden Morton
Publikováno v:
Chemical Engineering Science. 66:1640-1648
The purpose of this study was to characterise the cohesive behaviour of powders by measuring aerosolisation at a sequence of different flow rates, i.e. flow titration. Salbutamol sulphate and Lactohale 300 were model cohesive materials. Laser diffrac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40e5f90ea9fac61fb859ffef5922d6da
https://doi.org/10.1016/j.ces.2010.12.044
https://doi.org/10.1016/j.ces.2010.12.044
Autor:
David Alexander Vodden Morton, Michelle P. McIntosh, Srinivas Ravindra Babu Behara, Peter Stewart, Paul Kippax, Ian Larson
Publikováno v:
European Journal of Pharmaceutical Sciences. 42:210-219
Purpose The purpose of this study was to understand the behaviour of cohesive powder mixtures of salbutamol sulphate (SS) and micronized lactose (LH300) at ratios of SS:LH300 of 1:1, 1:2, 1:4 and 1:8 under varying air flow conditions. Methods Aerosol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ea8bb79f10d264d7a539d7f022d7ca1
https://doi.org/10.1016/j.ejps.2010.11.008
https://doi.org/10.1016/j.ejps.2010.11.008
Autor:
Philippe Begat, Jagdeep Shur, John N. Staniforth, Robert Price, David Alexander Vodden Morton, Paul Kippax
Publikováno v:
Journal of Pharmaceutical Sciences. 98:2770-2783
The aim of this study was to determine the aerosolisation and aerodynamic properties of model inhalation particles (salbutamol sulphate and budesonide) upon coprocessing with force control agents (FCAs)-leucine, lecithin and magnesium stearate. Copro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::441b8ee0526df008e8e452935988f30c
https://doi.org/10.1002/jps.21629
https://doi.org/10.1002/jps.21629
Publikováno v:
International Journal of Pharmaceutics. 371:99-105
Mathematical models are available which predict aerosol deposition in the respiratory system assuming that the aerosol concentration and size are constant during inhalation. In this study, we constructed a sinusoidal breathing model to calculate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9b42e2c915b330a5fde513c3b60bab8
https://doi.org/10.1016/j.ijpharm.2008.12.027
https://doi.org/10.1016/j.ijpharm.2008.12.027
Publikováno v:
Powder Technology. 134:243-248
Ultrasonic attenuation spectroscopy is a recently developed technique for rapid characterisation of particulate suspensions at high concentrations. Implementation of the full Epstein–Carhart–Allegra–Hawley model, which is used to transform ultr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1aade9fa3b12ad57994de8279499667c
https://doi.org/10.1016/j.powtec.2003.08.051
https://doi.org/10.1016/j.powtec.2003.08.051