Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Paul K. S. Chan"'
Autor:
Liuyang Cai, Hengyan Zhu, Qianqian Mou, Po Yee Wong, Linlin Lan, Cherrie W. K. Ng, Pu Lei, Man Kit Cheung, Daijuanru Wang, Eddy W. Y. Wong, Eric H. L. Lau, Zenon W. C. Yeung, Ronald Lai, Katie Meehan, Sherwood Fung, Kwan Chee A. Chan, Vivian W. Y. Lui, Alfred S. L. Cheng, Jun Yu, Paul K. S. Chan, Jason Y. K. Chan, Zigui Chen
Publikováno v:
npj Biofilms and Microbiomes, Vol 10, Iss 1, Pp 1-16 (2024)
Abstract Dysbiosis of the human oral microbiota has been reported to be associated with oral cavity squamous cell carcinoma (OSCC) while the host-microbiota interactions with respect to the potential impact of pathogenic bacteria on host genomic and
Externí odkaz:
https://doaj.org/article/6d1d6f4104b84fe4850c86de36df8238
Autor:
Baozhen Huang, Jinghan Huang, Nim Hang Chiang, Zigui Chen, Grace Lui, Lowell Ling, Mike Yat Wah Kwan, Joshua Sung Chih Wong, Phoebe Qiaozhen Mak, Janet Wan Hei Ling, Ivan Cheuk San Lam, Rita Wai Yin Ng, Xingyan Wang, Ruonan Gao, David Shu-Cheong Hui, Suk Ling Ma, Paul K. S. Chan, Nelson Leung Sang Tang
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
IntroductionThere is insufficient understanding on systemic interferon (IFN) responses during COVID-19 infection. Early reports indicated that interferon responses were suppressed by the coronavirus (SARS-CoV-2) and clinical trials of administration
Externí odkaz:
https://doaj.org/article/d1b469ff536f4a2e87c8aeab755b005d
Autor:
Owen N. W. Leung, Nicholas K. H. Chiu, Samuel Y. S. Wong, Pim Cuijpers, Jordi Alonso, Paul K. S. Chan, Grace Lui, Eliza Wong, Ronny Bruffaerts, Benjamin H. K. Yip, Philippe Mortier, Gemma Vilagut, Dora Kwok, Linda C. W. Lam, Ronald C. Kessler, Arthur D. P. Mak
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract This study examined the latent structure of the broad range of complex neuropsychiatric morbidities occurring 1 year after COVID-19 infection. As part of the CU-COVID19 study, 248 (response rate=39.3%) of 631 adults hospitalized for COVID-19
Externí odkaz:
https://doaj.org/article/55e4c3380b414080993901ffe8fea5d4
Autor:
Bei Huang, Steven W. H. Chau, Yaping Liu, Joey W. Y. Chan, Jing Wang, Suk Ling Ma, Jihui Zhang, Paul K. S. Chan, Yun Kit Yeoh, Zigui Chen, Li Zhou, Sunny Hei Wong, Vincent C. T. Mok, Ka Fai To, Hei Ming Lai, Simon Ng, Claudia Trenkwalder, Francis K. L. Chan, Yun Kwok Wing
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract The microbiota-gut-brain axis has been suggested to play an important role in Parkinson’s disease (PD). Here we performed a cross-sectional study to profile gut microbiota across early PD, REM sleep behavior disorder (RBD), first-degree re
Externí odkaz:
https://doaj.org/article/c3bbdd259c714201900d6ae7b4f3e793
Autor:
Man Kit Cheung, Ting Fan Leung, Wing Hung Tam, Agnes S. Y. Leung, Oi Man Chan, Rita W. Y. Ng, Jennifer W. K. Yau, Lai-yuk Yuen, Sylvia L. Y. Tong, Wendy C. S. Ho, Apple C. M. Yeung, Zigui Chen, Paul K. S. Chan
Publikováno v:
mSystems, Vol 8, Iss 5 (2023)
ABSTRACT The first few years of life is a key period for the development of the gut microbiome. However, our current understanding of this topic is largely biased toward Western populations. In this study, we characterized the development and determi
Externí odkaz:
https://doaj.org/article/ac4b79eceff548bb80c34d9d75444898
Autor:
Yu P. Song, Man F. Tang, Agnes S. Y. Leung, Kin P. Tao, Oi M. Chan, Gary W. K. Wong, Paul K. S. Chan, Renee W. Y. Chan, Ting F. Leung
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 5 (2023)
ABSTRACT Rhinovirus (RV) is the leading pathogen causing childhood wheezing, with rhinovirus C (RV-C) species reported to cause asthma exacerbation. Allele A of single-nucleotide polymorphism (SNP) CDHR3_rs6967330 upregulates epithelial expression of
Externí odkaz:
https://doaj.org/article/cae431285db24543beb675014e19063d
Autor:
Qin Liu, Qi Su, Fen Zhang, Hein M. Tun, Joyce Wing Yan Mak, Grace Chung-Yan Lui, Susanna So Shan Ng, Jessica Y. L. Ching, Amy Li, Wenqi Lu, Chenyu Liu, Chun Pan Cheung, David S. C. Hui, Paul K. S. Chan, Francis Ka Leung Chan, Siew C. Ng
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Here, by performing an integrative multi-omics analysis coupled to clinical features of COVID-19 patients prospectively followed for up to 6 month, the authors identify specific gut microbiome patterns associated with disease severity and development
Externí odkaz:
https://doaj.org/article/9c82b02d370c4f8693fdb8e528652f7e
Autor:
Zigui Chen, Amy B. W. Chan, Lok-Sang Kam, Man-Hin Chan, Jason Y. K. Chan, Wai-Tung Lee, Chit Chow, Siaw S. Boon, Chichao Xia, Brian Lam, Suki Lam, Rita W. Y. Ng, Wendy C. S. Ho, Eddy W. H. Lam, Christopher K. C. Lai, Paul K. S. Chan
Publikováno v:
Cancers, Vol 16, Iss 1, p 226 (2024)
The incidence of human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC) is rising in the West, but little is known in Asia. This study elucidated changes in the incidence and HPV-positive portion of OPSCC in Hong Kong. Da
Externí odkaz:
https://doaj.org/article/a246cd73b1c7421584a1987eb5ae8a96
Autor:
Lowell Ling, Christopher K.C. Lai, Grace Lui, Apple Chung Man Yeung, Hiu Ching Chan, Chung Hon Shawn Cheuk, Adonia Nicole Cheung, Lok Ching Chang, Lok Ching Sandra Chiu, Jack Zhenhe Zhang, Wai-Tat Wong, David S. C. Hui, Chun Kwok Wong, Paul K. S. Chan, Zigui Chen
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Longitudinal studies on upper respiratory tract microbiome in coronavirus disease 2019 (COVID-19) without potential confounders such as antimicrobial therapy are limited. The objective of this study is to assess for longitudinal changes in the upper
Externí odkaz:
https://doaj.org/article/f791d26a338f4956af53a62baa13af68
Autor:
Man Kit Cheung, Sylvia L. Y. Tong, Martin C. S. Wong, Jason Y. K. Chan, Margaret Ip, Mamie Hui, Christopher K. C. Lai, Rita W. Y. Ng, Wendy C. S. Ho, Apple C. M. Yeung, Paul K. S. Chan, Zigui Chen
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 1 (2023)
ABSTRACT Recent studies have provided evidence on the presence of an oral–gut microbiota axis in gastrointestinal diseases; however, whether a similar axis exists in healthy individuals is still in debate. Here, we characterized the bacterial and f
Externí odkaz:
https://doaj.org/article/840a681132a4436399f65423fee389c8