Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Paul J. R. Spooner"'
NMR methods have been adopted to observe directly the characteristics of substrate binding to the galactose-H+ symport protein GalP, in its native environment, the inner membranes of Escherichia coli. Sedimented inner-membrane vesicles containing the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f848d043a31fb198c512f2329041182
https://doi.org/10.1073/pnas.91.9.3877
https://doi.org/10.1073/pnas.91.9.3877
Publikováno v:
Scopus-Elsevier
The influence of the antiviral peptide, carbobenzoxy-D-phenylalanyl-L-phenylalanylglycine (ZfFG), on the average conformation of phosphatidylcholine in hydrated bilayers was investigated with multinuclear solid state magnetic resonance (NMR). Phospha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7c8681e9e06da5fdd23dabe63dd09e6
https://ora.ox.ac.uk/objects/uuid:a7a30e0e-a160-47eb-b136-8875ca2c8e15
https://ora.ox.ac.uk/objects/uuid:a7a30e0e-a160-47eb-b136-8875ca2c8e15
A phosphotriester approach is used to access the complex phospholipid, cardiolipin (1) with polyunsaturated fatty acid chains. The synthetic method allows the specific incorporation of isotopic labels within the molecule and sets up the desired confi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f2d80d82d9619478aa0a57ded14c1c2
https://doi.org/10.1016/s0040-4039(97)10829-2
https://doi.org/10.1016/s0040-4039(97)10829-2
Autor:
S. W. Homans, W. J. O'reilly, Peter J. F. Henderson, Paul J. R. Spooner, Anthony Watts, Nicholas G. Rutherford
The weak binding of sugar substrates fails to induce any quantifiable physical changes in the L-fucose-H+ symport protein, FucP, from Escherichia coli, and this protein lacks any strongly binding ligands for competitive binding assays. Access to subs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be5fd14b9c5eef31635b041eae62d657
https://ora.ox.ac.uk/objects/uuid:172676df-e815-473e-acc9-2ba1415bd02f
https://ora.ox.ac.uk/objects/uuid:172676df-e815-473e-acc9-2ba1415bd02f
1,2-Isopropylidene-3-methoxyethoxymethyl- sn -glycerol ( 2 ) is used to access complex polyunsaturated diacylglycerols of high optical purity such as 1,2-dilinoleoyl- sn -glycerol ( 5 ). Using a similar methodology its enantiomer, 2,3-dilinoleoyl- sn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::498de5294e34ca35ddbbde8715f774e2
https://doi.org/10.1016/s0040-4039(00)99448-6
https://doi.org/10.1016/s0040-4039(00)99448-6
Autor:
Kay E. Gottschalk, Shimon Schuldiner, Anthony Watts, Horst Kessler, Paul J. R. Spooner, Clemens Glaubitz, Adriane Gröger
The binding of tetraphenylphosphonium (TPP+) to EmrE, a membrane-bound, 110 residue Escherichia coli multidrug transport protein, has been observed by 31P cross-polarisation–magic-angle spinning nuclear magnetic resonance spectroscopy (CP–MAS NMR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84777c8678554f48487625160d60ce7f
https://doi.org/10.1016/s0014-5793(00)01916-5
https://doi.org/10.1016/s0014-5793(00)01916-5
Autor:
Willem J. DeGrip, Johan Lugtenburg, Anthony Watts, Paul J. R. Spooner, Michiel A. Verhoeven, Petra H. M. Bovee-Geurts, Arthur M.A. Pistorius, Jonathan M. Sharples, Scott C. Goodall
Publikováno v:
Journal of Molecular Biology, 343, 3, pp. 719-30
Journal of Molecular Biology, 343, 719-30
Journal of Molecular Biology, 343, 719-30
Contains fulltext : 57945.pdf (Publisher’s version ) (Closed access) The current view that the beta-ionone ring of the rhodopsin chromophore vacates its binding pocket within the protein early in the photocascade has been adopted in efforts to prov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbd1039c4da4ece456efb5a9347085e6
https://doi.org/10.1016/j.jmb.2004.08.049
https://doi.org/10.1016/j.jmb.2004.08.049
Autor:
Anthony Watts, J. Lugtenburg, Jonathan M. Sharples, Clemens Glaubitz, Michiel A. Verhoeven, Paul J. R. Spooner
Publikováno v:
Biochemistry. 41:7549-7555
Rotational resonance solid state nuclear magnetic resonance has been used to determine the relative orientation of the beta-ionone ring and the polyene chain of the chromophore 11-Z-retinylidene of rhodopsin in rod outer segment membranes from bovine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e881a481fc04cd577d70b652ebcc3cec
https://doi.org/10.1021/bi020007o
https://doi.org/10.1021/bi020007o
Autor:
Saffron E. Rankin, Anthony Watts, Teresa J. T. Pinheiro, Paul J. R. Spooner, Andrzej A. Duralski
Publikováno v:
Biophysical Journal. 65(1):106-112
Deuterium and phosphorus nuclear magnetic resonance (NMR) has been used to investigate the dynamics of slow motional processes induced in bilayer cardiolipin upon binding with cytochrome c. 31P NMR line shapes suggest that protein binding induces les
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ec27e1da235740169de9a906ad5aa02