Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Paul J. Myers"'
Publikováno v:
Western Journal of Emergency Medicine, Vol 15, Iss 7, Pp 840-840 (2014)
n/a
Externí odkaz:
https://doaj.org/article/d656fcba437149078c12dca73db9004f
Autor:
Brooke A. Brown, Paul J. Myers, Sara J. Adair, Jason R. Pitarresi, Shiv K. Sah-Teli, William S. Hart, Michelle Barbeau, Kelsey Leong, Nicholas Seyler, William Kane, Kyoung Eun Lee, Edward Stelow, M. Celeste Simon, Peppi Koivunen, Todd W. Bauer, Ben Z. Stanger, Matthew J. Lazzara
Here, we show that hypoxia drives especially long-lasting epithelial-mesenchymal transition (EMT) in pancreatic ductal adenocarcinoma (PDAC) primarily through a positive-feedback histone methylation-MAPK signaling axis. We find that neoplastic PDAC c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fc3704190032dba40de537af9b4484b
https://doi.org/10.1101/2022.10.19.512869
https://doi.org/10.1101/2022.10.19.512869
Autor:
Shayn M. Peirce, Matthew J. Lazzara, Kenny M. Hansson, Maria Wågberg, Peter Gennemark, Regina Fritsche-Danielson, Joachim Almquist, S. Michaela Rikard, Anthony C. Bruce, Paul J. Myers
Publikováno v:
Cellular and Molecular Bioengineering
Introduction Pharmacologic approaches for promoting angiogenesis have been utilized to accelerate healing of chronic wounds in diabetic patients with varying degrees of success. We hypothesize that the distribution of proangiogenic drugs in the wound
A Spatially Resolved EGFR Signaling Model Predicts the Length Scale of GAB1-SHP2 Complex Persistence
Autor:
Paul J. Myers, Christopher M. Furcht, Itziar Pinilla-Macua, Alexander Sorkin, William M. Deen, Matthew J. Lazzara
Activation of receptor tyrosine kinases (RTKs) promotes the intracellular assembly of protein complexes formed through phosphotyrosine-SH2 domain linkages. These interactions are weak and reversible, and the dephosphorylation of uncomplexed phosphory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28bf11abb6a453dcca79a63b8692258c
https://doi.org/10.1101/2021.11.08.467801
https://doi.org/10.1101/2021.11.08.467801
Autor:
Brooke A. Brown, Paul J. Myers, Sara J. Adair, Jason R. Pitarresi, Shiv Sah Teli, Peppi Karppinen, Ben Z. Stanger, Todd W. Bauer, Matthew J. Lazzara
Publikováno v:
Cancer Research. 82:C054-C054
Pancreatic ductal adenocarcinoma (PDAC) tumors are poorly vascularized and exhibit regions of hypoxia. Here, we demonstrate that this feature of the tumor microenvironment promotes epithelial-mesenchymal transition (EMT), which occurs early in PDAC a
Autor:
Mark A Pitman, Brooke A. McGirr, Matthew J. Lazzara, Paul J. Myers, Julie L Hartz, Christopher D. Deppmann, Philip J Tubergen
Publikováno v:
eLS
Autor:
Samantha A Clayton, Paul J. Myers, Matthew J. Lazzara, Simon C. Watkins, Alexander Sorkin, Sachin V. Surve
Publikováno v:
Molecular Biology of the Cell
Activation of the epidermal growth factor (EGF) receptor (EGFR) at the cell surface initiates signaling through the RAS-RAF-MAPK/ERK1/2 pathway and receptor endocytosis. Whether this signaling continues from endosomes remains unclear, because RAS is
Autor:
DO Lindsay R. Newcomb, Bryan G Kane, Erin Ricart, DO Paul J Myers, DO Kayla R Long, RN Valerie Rupp, David M. Richardson, DO Megan C Urquhart
Publikováno v:
The Journal of nursing administration. 44(11)
Background Timely stocking of essential supplies in an emergency department (ED) is crucial to efficient and effective patient care. Objective The objective of this study was to decrease wasted nursing time in obtaining needed supplies in an ED throu
Publikováno v:
Western Journal of Emergency Medicine
Western Journal of Emergency Medicine, Vol 15, Iss 7, Pp 840-840 (2014)
Western Journal of Emergency Medicine, Vol 15, Iss 7, Pp 840-840 (2014)
Author(s): Myers, DO, Paul J.; Kane, MD, Kathleen E.; Porter, Bernadette G.; Mazzaccaro, MD, PhD, Richard J.