Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Paul J. Matheson"'
Autor:
Jessica L. Weaver, Jessica E. Schucht, Paul J. Matheson, Amy J. Matheson, Cameron A. Ghazi, Cynthia D. Downard, Richard Neal Garrison, Jason W. Smith
Publikováno v:
Journal of Investigative Surgery, Vol 33, Iss 9, Pp 803-812 (2020)
Background: Acute brain death (ABD) is associated with inflammation and lung injury. Direct peritoneal resuscitation (DPR) improves blood flow to the vital organs after ABD. DPR reduces lung injury, but the mechanism for this is unknown. Methods: Mal
Externí odkaz:
https://doaj.org/article/1758d95bf02847c4ac3d09ebaf26c558
Publikováno v:
Journal of the American College of Surgeons. 235(4)
Intestinal injury from resuscitated hemorrhagic shock (HS) disrupts intestinal microvascular flow and causes enterocyte apoptosis, intestinal barrier breakdown, and injury to multiple organs. Fresh frozen plasma (FFP) resuscitation or directed perito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8f2c34b6beb390da76d536ab99e2e48
https://pubmed.ncbi.nlm.nih.gov/36106867
https://pubmed.ncbi.nlm.nih.gov/36106867
Autor:
Brian G Harbrecht, Khaled J M Alkhateeb, Paul J. Matheson, Jason W. Smith, Graham R Ashkettle, Logan Bond, Shawn Jones, Jessica E Schucht
Publikováno v:
Journal of Trauma and Acute Care Surgery. 89:649-657
Impaired intestinal microvascular perfusion following resuscitated hemorrhagic shock (HS) leads to ischemia-reperfusion injury, microvascular dysfunction, and intestinal epithelial injury, which contribute to the development of multiple organ dysfunc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ab210ce519125e9d08dddb8f0dea657
https://doi.org/10.1097/ta.0000000000002847
https://doi.org/10.1097/ta.0000000000002847
Autor:
Jason W. Smith, Graham R Ashkettle, Logan Bond, Paul J Matheson, Brian G. Harbrecht, Jessica E Schucht
Publikováno v:
The journal of trauma and acute care surgery. 90(1)
INTRODUCTION Hemorrhagic shock (HS) and resuscitation (RES) cause ischemia-induced intestinal permeability due to intestinal barrier breakdown, damage to the endothelium, and tight junction (TJ) complex disruption between enterocytes. The effect of h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cab7b53f7b799a6823658e8906ba3f74
https://pubmed.ncbi.nlm.nih.gov/32910075
https://pubmed.ncbi.nlm.nih.gov/32910075
Autor:
Mark A. Eid, C.D. Downard, Jessica L. Weaver, Samuel A. Matheson, Matthew A Wilson, Paul J. Matheson, Victoria S Graham, Jason W Smith
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 315:L339-L347
Conventional resuscitation (CR) of hemorrhagic shock (HS), a significant cause of trauma mortality, is intravenous blood and fluids. CR restores central hemodynamics, but vital organ flow can drop, causing hypoperfusion, hypoxia, damage-associated mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcbc90389f46f53b0c1613eb0d71bec4
https://doi.org/10.1152/ajplung.00183.2017
https://doi.org/10.1152/ajplung.00183.2017
Autor:
Jason W. Smith, Cynthia Downard, Brian G. Harbrecht, R. Neal Garrison, Victoria S Graham, Amy Matheson, Paul J. Matheson, Jessica L. Weaver
Publikováno v:
Journal of Trauma and Acute Care Surgery. 84:265-272
Background The profound inflammatory response associated with brain death is frequently cited as the reason organs procured from brain dead donors are associated with worse graft function. The intestine releases inflammatory mediators in other types
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::394396c132f56d3941958f86ad45e40a
https://doi.org/10.1097/ta.0000000000001742
https://doi.org/10.1097/ta.0000000000001742
Autor:
R. Neal Garrison, Glen A. Franklin, Paul J. Matheson, Brian G. Harbrecht, J. David Richardson, Jason W. Smith
Publikováno v:
Journal of the American College of Surgeons. 224:396-404
Peritoneal resuscitation (PR) represents a unique modality of treatment for severely injured trauma patients requiring damage control surgery. These data represent the outcomes of a single institution randomized controlled trial into the efficacy of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30d5d30cd56cfca0bd108b3e201d709d
https://doi.org/10.1016/j.jamcollsurg.2016.12.047
https://doi.org/10.1016/j.jamcollsurg.2016.12.047
Autor:
Ryan T. Hurt, R. Neal Garrison, Paul J. Matheson, Jason W. Smith, Jessica L. Weaver, Cynthia D. Downard, Craig J. McClain
Publikováno v:
Journal of the American College of Surgeons. 223:68-75
MicroRNAs (miRNAs) are small segments of noncoding RNA that regulate gene expression and protein function, and therefore are key regulators of cellular processes including those of the inflammatory cascade after hemorrhagic shock (HS). We have previo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aecd401c8644e9d0bfe9c1d87446d4b4
https://doi.org/10.1016/j.jamcollsurg.2016.03.024
https://doi.org/10.1016/j.jamcollsurg.2016.03.024
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c137964a030b31d131cccaef476cc428
https://doi.org/10.1096/fasebj.2020.34.s1.09756
https://doi.org/10.1096/fasebj.2020.34.s1.09756
Autor:
Jessica L. Weaver, Amy Matheson, Cynthia D. Downard, Jason W. Smith, Victoria S Graham, Richard N. Garrison, Paul J. Matheson
Publikováno v:
American journal of physiology. Renal physiology. 315(2)
Brain death is associated with significant inflammation within the kidneys, which may contribute to reduced graft survival. Direct peritoneal resuscitation (DPR) has been shown to reduce systemic inflammation after brain death. To determine its effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0d66a7564807e9e2c3635e7164e2609
https://pubmed.ncbi.nlm.nih.gov/29667907
https://pubmed.ncbi.nlm.nih.gov/29667907