Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Paul J. Matheson"'
Autor:
Jessica L. Weaver, Jessica E. Schucht, Paul J. Matheson, Amy J. Matheson, Cameron A. Ghazi, Cynthia D. Downard, Richard Neal Garrison, Jason W. Smith
Publikováno v:
Journal of Investigative Surgery, Vol 33, Iss 9, Pp 803-812 (2020)
Background: Acute brain death (ABD) is associated with inflammation and lung injury. Direct peritoneal resuscitation (DPR) improves blood flow to the vital organs after ABD. DPR reduces lung injury, but the mechanism for this is unknown. Methods: Mal
Externí odkaz:
https://doaj.org/article/1758d95bf02847c4ac3d09ebaf26c558
Publikováno v:
The Journal of surgical research [J Surg Res] 1998 Feb 15; Vol. 75 (1), pp. 90-4.
Publikováno v:
The Journal of surgical research. 75(1)
Copyright
Publikováno v:
Journal of the American College of Surgeons. 235(4)
Intestinal injury from resuscitated hemorrhagic shock (HS) disrupts intestinal microvascular flow and causes enterocyte apoptosis, intestinal barrier breakdown, and injury to multiple organs. Fresh frozen plasma (FFP) resuscitation or directed perito
Autor:
Brian G Harbrecht, Khaled J M Alkhateeb, Paul J. Matheson, Jason W. Smith, Graham R Ashkettle, Logan Bond, Shawn Jones, Jessica E Schucht
Publikováno v:
Journal of Trauma and Acute Care Surgery. 89:649-657
Impaired intestinal microvascular perfusion following resuscitated hemorrhagic shock (HS) leads to ischemia-reperfusion injury, microvascular dysfunction, and intestinal epithelial injury, which contribute to the development of multiple organ dysfunc
Autor:
Jason W. Smith, Graham R Ashkettle, Logan Bond, Paul J Matheson, Brian G. Harbrecht, Jessica E Schucht
Publikováno v:
The journal of trauma and acute care surgery. 90(1)
INTRODUCTION Hemorrhagic shock (HS) and resuscitation (RES) cause ischemia-induced intestinal permeability due to intestinal barrier breakdown, damage to the endothelium, and tight junction (TJ) complex disruption between enterocytes. The effect of h
Autor:
Mark A. Eid, C.D. Downard, Jessica L. Weaver, Samuel A. Matheson, Matthew A Wilson, Paul J. Matheson, Victoria S Graham, Jason W Smith
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 315:L339-L347
Conventional resuscitation (CR) of hemorrhagic shock (HS), a significant cause of trauma mortality, is intravenous blood and fluids. CR restores central hemodynamics, but vital organ flow can drop, causing hypoperfusion, hypoxia, damage-associated mo
Autor:
Jason W. Smith, Cynthia Downard, Brian G. Harbrecht, R. Neal Garrison, Victoria S Graham, Amy Matheson, Paul J. Matheson, Jessica L. Weaver
Publikováno v:
Journal of Trauma and Acute Care Surgery. 84:265-272
Background The profound inflammatory response associated with brain death is frequently cited as the reason organs procured from brain dead donors are associated with worse graft function. The intestine releases inflammatory mediators in other types
Autor:
R. Neal Garrison, Glen A. Franklin, Paul J. Matheson, Brian G. Harbrecht, J. David Richardson, Jason W. Smith
Publikováno v:
Journal of the American College of Surgeons. 224:396-404
Peritoneal resuscitation (PR) represents a unique modality of treatment for severely injured trauma patients requiring damage control surgery. These data represent the outcomes of a single institution randomized controlled trial into the efficacy of
Autor:
Ryan T. Hurt, R. Neal Garrison, Paul J. Matheson, Jason W. Smith, Jessica L. Weaver, Cynthia D. Downard, Craig J. McClain
Publikováno v:
Journal of the American College of Surgeons. 223:68-75
MicroRNAs (miRNAs) are small segments of noncoding RNA that regulate gene expression and protein function, and therefore are key regulators of cellular processes including those of the inflammatory cascade after hemorrhagic shock (HS). We have previo