Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Paul J. Laybourn"'
Publikováno v:
The American Biology Teacher. 81:513-519
Much evidence supports the role of writing-to-learn (WTL) assignments in improving student learning and argumentation skills. However, designing effective assignments can be challenging for instructors. We describe a process for modifying WTL assignm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c640031a312ed4f5dad0d273dcc22873
https://doi.org/10.1525/abt.2019.81.7.513
https://doi.org/10.1525/abt.2019.81.7.513
Publikováno v:
BioScience. 68:445-454
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::921bf1e80462c4ebe6f7d1f48b63e5ac
https://doi.org/10.1093/biosci/biy042
https://doi.org/10.1093/biosci/biy042
Autor:
Kasey L. Konesky, Paul J. Laybourn
Publikováno v:
Methods. 41:259-270
We have optimized a recombinant chromatin assembly system that properly incorporates core histones and histone H1 into a chromatin template containing a natural promoter sequence. This article provides a step-by-step procedure for expression and puri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee23df307dd4404a7014d730edc8529f
https://doi.org/10.1016/j.ymeth.2006.11.004
https://doi.org/10.1016/j.ymeth.2006.11.004
Publikováno v:
Journal of Virology. 80:10542-10553
Upon infection of human T-cell leukemia virus type 1 (HTLV-1), the provirus is integrated into the host cell genome and subsequently packaged into chromatin that contains histone H1. Consequently, transcriptional activation of the virus requires over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59e5ff89a55f14a420ebbb4d9d3ce706
https://doi.org/10.1128/jvi.00631-06
https://doi.org/10.1128/jvi.00631-06
Publikováno v:
Journal of Biological Chemistry. 281:13075-13082
The human T-cell leukemia virus type 1 (HTLV-1) is integrated into the host cell DNA and assembled into nucleosomes. Within the repressive chromatin environment, the virally encoded Tax protein mediates the recruitment of the coactivators CREB-bindin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d1a72c38e8a7e02be8155b2d05f6d47
https://doi.org/10.1074/jbc.m512193200
https://doi.org/10.1074/jbc.m512193200
Autor:
Paul J. Laybourn, Sriwan Wongwisansri
Publikováno v:
Eukaryotic Cell. 4:1387-1395
The histone deacetylase Rpd3p functions as a transcriptional repressor of a diverse set of genes, including PHO5 . Here we describe a novel role for RPD3 in the regulation of phosphate transporter Pho84p retention in the cytoplasmic membrane. We show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f21e0dad203183935985739afe0b1b1f
https://doi.org/10.1128/ec.4.8.1387-1395.2005
https://doi.org/10.1128/ec.4.8.1387-1395.2005
Autor:
David J. Tremethick, Danny Rangasamy, Young-Jun Park, Paul J. Laybourn, Yunhe Bao, Simona Rosu, Karolin Luger, Kasey L. Konesky, Pamela N. Dyer
Publikováno v:
The EMBO Journal. 23:3314-3324
H2A.Bbd is an unusual histone variant whose sequence is only 48% conserved compared to major H2A. The major sequence differences are in the docking domain that tethers the H2A-H2B dimer to the (H3-H4)(2) tetramer; in addition, the C-terminal tail is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5328c23eb0453dd4c9c0901d4e6552f
https://doi.org/10.1038/sj.emboj.7600316
https://doi.org/10.1038/sj.emboj.7600316
Publikováno v:
Journal of Biological Chemistry. 277:49459-49465
The human T-cell leukemia virus (HTLV-I)-encoded Tax protein is a potent transcriptional activator that stimulates expression of the integrated provirus. Biochemical studies indicate that Tax, together with cellular transcription factors, interacts w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e210bcb7774ee56a76f5e7a2a30cc56
https://doi.org/10.1074/jbc.m209566200
https://doi.org/10.1074/jbc.m209566200
Publikováno v:
Journal of Biological Chemistry. 277:31038-31047
The PHO5 gene promoter is an important model for the study of gene regulation in the context of chromatin. Upon PHO5 activation the chromatin structure is reconfigured, but the mechanism of this transition remains unclear. Using templates reconstitut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bee9410ac2d8830bece09de135f3b61
https://doi.org/10.1074/jbc.m204662200
https://doi.org/10.1074/jbc.m204662200
Autor:
David R. Moss, Paul J. Laybourn
Publikováno v:
Molecular Microbiology. 36:1293-1305
The mechanisms of transcription repression and derepression in vivo are not fully understood. We have obtained evidence that begins to clarify the minimum requirements for counteracting nucleosomal repression in vivo. Location of the TATA element nea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc7c0f02f47f719d956cde8e5b12c56f
https://doi.org/10.1046/j.1365-2958.2000.01940.x
https://doi.org/10.1046/j.1365-2958.2000.01940.x