Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Paul J. Kruzich"'
Autor:
Paul J. Kruzich, Ansong Ping
Publikováno v:
Pharmacology Biochemistry and Behavior. 90:492-496
Investigation of the role of choice between use of drugs of abuse and pursuit of alternative non-drug reinforcers is receiving greater attention. An understanding of the determinants influencing choice between drugs and alternative reinforcers will e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1398a05ed608713f7db0f4b867c2e698
https://doi.org/10.1016/j.pbb.2008.04.009
https://doi.org/10.1016/j.pbb.2008.04.009
Autor:
Paul J. Kruzich, David K. Grandy, B. Matthew Joyce, Clelland R. Gash, Erin C. Rutherford, Greg A. Gerhardt, Paul E.A. Glaser, Stewart P. Surgener, Katherine L. Suchland, Theresa Currier Thomas
Publikováno v:
Journal of Neuroscience Methods. 166:306-314
Dopamine D4 receptor (D4R) knockout mice (D4R-/-) provided for unique neurochemical studies designed to understand D4R contributions to dopamine (DA) regulation. In this study, post-mortem brain tissue content of DA did not differ between D4R+/+ and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39d0bbe88a65931542dd33f06bf6c99a
https://doi.org/10.1016/j.jneumeth.2007.03.009
https://doi.org/10.1016/j.jneumeth.2007.03.009
Autor:
Paul J. Kruzich
Publikováno v:
Brain Research. 1149:165-171
Inbred strains of mice are valuable tools for determining the impact of genes and the environment on behavior. However, use of mice in intravenous (iv) cocaine self-administration (SA) extinction/reinstatement paradigms has yielded mixed results. Mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72210f66c5339cc28374b7a68d9e7877
https://doi.org/10.1016/j.brainres.2007.02.037
https://doi.org/10.1016/j.brainres.2007.02.037
Publikováno v:
Cognitive, Affective, & Behavioral Neuroscience. 6:86-90
Dopamine is critical for directing goal-oriented behavior. We investigated dopamine D2 receptor involvement in reversal learning and reinforcement efficacy in mice lacking functional dopamine D2 receptors and their heterozygous and wild-type litterma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3890acc7a61554061a13b9a2de88da4a
https://doi.org/10.3758/cabn.6.1.86
https://doi.org/10.3758/cabn.6.1.86
Publikováno v:
Synapse. 47:243-249
Repeated intake of opioids is associated with dose escalation and alterations in signal transduction at the G-protein-coupled receptor level. The current study utilized two experiments to identify factors in rats that influence consumption rates such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::899a7687fcf835b56dd5224aac9f4b50
https://doi.org/10.1002/syn.10173
https://doi.org/10.1002/syn.10173
Publikováno v:
Behavioral Neuroscience. 115:1086-1092
The present study investigated the ability of a light and tone (LT) compound stimulus paired with cocaine infusions to reinstate cocaine-seeking behavior. Rats were trained to self-administer cocaine in the presence or absence of the LT during daily
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e76c23f29f7a377593e720c121b51af9
https://doi.org/10.1037/0735-7044.115.5.1086
https://doi.org/10.1037/0735-7044.115.5.1086
Autor:
Paul J. Kruzich, Ronald E. See
Publikováno v:
Brain Research. 875:35-43
A widely postulated mechanism of action for the atypical profile of many novel antipsychotic drugs (APDs) is their relatively high affinity for 5-HT(2) receptors. The present study investigated motor function and striatal dopamine (DA) efflux and met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8de8342de66d9fe2f64483fdd052fff5
https://doi.org/10.1016/s0006-8993(00)02574-9
https://doi.org/10.1016/s0006-8993(00)02574-9
Publikováno v:
Psychobiology. 28:383-386
In this study, we examined the importance of contingent access to a cocaine-related stimulus in the production of cocaine seeking following extinction of lever responding for cocaine. Rats self-administered cocaine for 2 weeks in daily 3-h sessions u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff385b44ad46cda5853a0275ad02c9ae
https://doi.org/10.3758/bf03331995
https://doi.org/10.3758/bf03331995
Publikováno v:
Drug and Alcohol Dependence. 57:41-49
Previous studies have demonstrated that conditioned stimuli can increase responding on a drug-associated lever after extinction from drug self-administration. The present study investigated singular stimuli (tone or light) or a compound stimulus (ton
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::706dbfb26b90d081676316531e314cfb
https://doi.org/10.1016/s0376-8716(99)00043-5
https://doi.org/10.1016/s0376-8716(99)00043-5
Publikováno v:
Pharmacology Biochemistry and Behavior. 60:167-173
Neuroleptic-induced orofacial movements in rats have been widely utilized as an animal model of tardive dyskinesia (TD). The present study investigated the role of the oral motor cortex in these movements by applying direct cortical stimulation in ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44b94d0415b43285f3fd9739fbe03938
https://doi.org/10.1016/s0091-3057(97)00587-x
https://doi.org/10.1016/s0091-3057(97)00587-x