Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Paul J. Kaminski"'
Publikováno v:
mBio, Vol 11, Iss 4 (2020)
ABSTRACT High-risk human papillomaviruses (HPVs) constitutively activate the ataxia telangiectasia and Rad3-related (ATR) DNA damage response pathway, and this is required for viral replication. In fibroblasts, activated ATR regulates transcription o
Externí odkaz:
https://doaj.org/article/5d0cf5180f0043dbaf1cd79c8ed96a12
Autor:
Laimonis A. Laimins, Yan Li, Jorge Andrade, Junfen Xu, Shiyuan Hong, Paul J. Kaminski, Paul Hoover
Publikováno v:
Oncogene
High-risk human papillomaviruses (HPVs) constitutively activate ataxia telangiectasia mutated (ATM) and ataxia telangiectasia- and Rad3-related (ATR) DNA damage repair pathways for viral genome amplification. HPVs activate these pathways through the
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
mBio
mBio
High-risk human papillomaviruses (HPVs) infect epithelial cells and induce viral genome amplification upon differentiation. HPV proteins activate DNA damage repair pathways by inducing high numbers of DNA breaks in both viral and cellular DNAs.