Phase Ⅰ/Ⅱ, Double-Masked, Randomized, Vehicle-Controlled Study of H-1337 Ophthalmic Solution for Glaucoma and Ocular Hypertension

Autor: Paul J. Hartman, David L. Cooke, Henry H. Hsu, Jeanette Stewart, Kengo Sumi, Yoko Yoshida, Hiroyoshi Hidaka, Gary D. Novack

Publikováno v: Ophthalmology. Glaucoma, vol 6, iss 2

PurposeTo perform a phase Ⅰ/Ⅱ evaluation of an H-1337 ophthalmic solution in subjects with primary open-angle glaucoma (POAG) or ocular hypertension (OHT).DesignThis was a phase I/II, randomized, double-masked, vehicle-controlled, dose-response s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87f1354718658aa2f4ba91fbb21c4e60
https://doi.org/10.1016/j.ogla.2022.08.015

Phase 3, Randomized, 20-Month Study of Bimatoprost Implant in Open-Angle Glaucoma and Ocular Hypertension (ARTEMIS 1)

Autor: Felipe A. Medeiros, Thomas R. Walters, Miriam Kolko, Michael Coote, Marina Bejanian, Margot L. Goodkin, Qiang Guo, Jane Zhang, Michael R. Robinson, Robert N. Weinreb, Ashish Agar, Renuka Bathijia, Lance Liu, Tim Roberts, Christoph Faschinger, Clemens Vass, Nathalie Collignon, Ana Claudia Alves Pereira, Rubens Belfort de Mattos, Fernando Justino Dantas, Marcelo Jordao Lopes da Silva, Fabio Kanadani, Leopoldo Magacho dos Santos Silva, Tiago Prata, Daniella Bach-Holm, Jimmy Lai, Clement Tham, György Bátor, Lajos Szalczer, Balázs Varsányi, Eytan Blumenthal, Orna Geyer, Shmuel Lavartovsky, Tamar Pedut-Kloizman, Nir Shoham-Hazon, Silvio Lujan, Benjamin Abela, Robert E. Ang, Edgar U. Leuenberger, Harvey Uy, Maria Imelda Yap-Veloso, Piotr Fryczkowski, Piotr Jurowski, Bartlomiej Kalużny, Józef Kalużny, Marta Misiuk-Hojlo, Krystyna Raczynska, Wioletta Tomczyk-Dorozynska, Jaromir Wasyluk, Slawomir Zalewski, Tomasz Zarnowski, Julian Garcia Feijoó, Rafael Giménez-Gómez, Elena Milla Griño, Alfonso Antón López, Merce Guarro Miralles, Javier Montero Moreno, Vicente Polo, Enrique Cervera Taulet, Beatriz Ponte Zúñiga, Ying-Ying Chen, Yuan-Chieh Lee, Louis Alpern, Michael S. Berlin, Jacob Brubaker, Delmar Caldwell, Andrew Camp, Louis B. Cantor, Ronald Caronia, Charles J. Crane, Douglas Day, Eran Duzman, John Elfervig, Sherif El-Harazi, Richard Evans, Ann C. Fisher, William John Flynn, Charles Stephen Foster, Ronald Frenkel, Raj Goyal, Ronald Gross, Paul J. Hartman, William L. Haynes, Gary Jerkins, Janet Kim, Max Kim, Bradley Kwapiszeski, Benjamin Lambright, Christine Larsen, James Lehmann, Jeffrey H. Levenson, Dwayne Logan, Brian McMillan, Joseph R. Martel, Hylton Mayer, Felipe Medeiros, Sayoko Moroi, Andrew Moyes, Jonathan Myers, John Nairn, Steven Nielsen, Don Perez Ortiz, James Paauw, Vicky Pai, Joseph Panarelli, Abraham Park, Mujtaba A. Qazi, Nikola Ragusa, Douglas J. Rhee, Robert Rothman, Reginald Sampson, Samuel Seltzer, Anurag Shrivastava, Steven T. Simmons, Annette Sims, Mark A. Slabaugh, Scott Smetana, Oluwatosin Smith, Scott C. So, Ingeborg Stalmans, Jitendra Swarup, Jay Wallshein, Fiaz Zaman, Rui Zhang

Publikováno v: Medeiros, F A, Walters, T R, Kolko, M, Coote, M, Bejanian, M, Goodkin, M L, Guo, Q, Zhang, J, Robinson, M R, Weinreb, R N, ARTEMIS 1 Study Group, Agar, A, Coote, M, Bathijia, R, Bach-Holm, D, Walters, T R, Zaman, F & Zhang, R 2020, ' Phase 3, Randomized, 20-Month Study of Bimatoprost Implant in Open-Angle Glaucoma and Ocular Hypertension (ARTEMIS 1) ', Ophthalmology, vol. 127, no. 12, pp. 1627-1641 . https://doi.org/10.1016/j.ophtha.2020.06.018

Purpose To evaluate the intraocular pressure (IOP)-lowering efficacy and safety of 10- and 15-μg bimatoprost implant in subjects with open-angle glaucoma (OAG) and ocular hypertension (OHT) after initial and repeated administrations. Design Randomiz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6460ae378d48f231ab7646dd34d2e2a
https://pubmed.ncbi.nlm.nih.gov/32544560