Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Paul J. Furdon"'
Autor:
Richard P. Woychik, Ingo Hansmann, Paul J. Furdon, John G. Powell, Wen Ji Chen, Scott J. Bultman, Heajoon Y. Kwon, William O. Wilkison, Christiane Löffler, Anton-Lewis Usala
Publikováno v:
Proceedings of the National Academy of Sciences. 91:9760-9764
The agouti (a) locus in mouse chromosome 2 normally regulates coat color pigmentation. The mouse agouti gene was recently cloned and shown to encode a distinctive 131-amino acid protein with a consensus signal peptide. Here we describe the cloning of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bedef4d0d39a91091dbb55e4b88423cb
https://doi.org/10.1073/pnas.91.21.9760
https://doi.org/10.1073/pnas.91.21.9760
Autor:
Brian Champion, Cinda M. Boyer, Gerard M. Mcgeehan, James Nichols, Margrith Verghese, Judy P. Ways, Anne Truesdale, James G. Conway, Stephen E. Karp, Katherine M. Pryzwansky, Janet Warner, Andrew B. Mcelroy, J. David Becherer, Kevin M. Connolly, Sudha Kidao, Les Sekut, Frank J Schoenen, Paul J. Furdon, Robert C. Bast
Publikováno v:
Nature. 370:558-561
Tumour necrosis factor-alpha (TNF-alpha) is a potent pro-inflammatory agent produced primarily by activated monocytes and macrophages. TNF-alpha is synthesized as a precursor protein of M(r) 26,000 (26K) which is processed to a secreted 17K mature fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1cb164e2c78432b69587d89c2a0ae19
https://doi.org/10.1038/370558a0
https://doi.org/10.1038/370558a0
Autor:
John G. Gray, Gyan Chandra, William C. Clay, Sandra W. Stinnett, Stephen A. Haneline, Jennifer J. Lorenz, Indravadan R. Patel, G. Bruce Wisely, Paul J. Furdon, J. David Taylor, Thomas A. Kost
Publikováno v:
Molecular and Cellular Biology. 13:6678-6689
Transfection of U937 and THP-1 cells with a recombinant plasmid, pIL1(4.0kb)-CAT, containing 4 kb of the interleukin 1 beta (IL-1 beta) gene upstream regulatory sequence resulted in inducer-dependent expression of chloramphenicol acetyltransferase ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3544f5081a09a3f78bf2be120afb6e8e
https://doi.org/10.1128/mcb.13.11.6678
https://doi.org/10.1128/mcb.13.11.6678
Publikováno v:
Nucleic Acids Research. 11:1491-1505
A novel mutation in the anticodon stem of E. coli tRNA1Tyrsu3+ (G43 to U43) has been characterized. The gene coding for the mutant tRNA, carried by phage phi 80DHA61.3 a derivative of phi 80psu3+su0, produces only 20% of mature suppressor tRNA as com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72e16bdf7f703a797d03fb8bd28e50b3
https://doi.org/10.1093/nar/11.5.1491
https://doi.org/10.1093/nar/11.5.1491
Publikováno v:
Nucleic Acids Research. 14:5241-5254
In vitro splicing of human beta-globin pre-mRNA can be fully inhibited by treatment of the splicing extract with polyclonal antibodies against hnRNP core proteins prior to the addition of pre-mRNA. Inhibition of the first step in the splicing pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ebd2ac3146430f4e18adc57d1b30380
https://doi.org/10.1093/nar/14.13.5241
https://doi.org/10.1093/nar/14.13.5241
Autor:
Ryszard Kole, Paul J. Furdon
Publikováno v:
Proceedings of the National Academy of Sciences. 83:927-931
Human beta-globin mRNAs truncated in the second exon or in the first intron have been processed in vitro in a HeLa cell nuclear extract. Transcripts containing a fragment of the second exon as short as 53 nucleotides are efficiently spliced, whereas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24eb7d36826cf5f06b1412f5326f6491
https://doi.org/10.1073/pnas.83.4.927
https://doi.org/10.1073/pnas.83.4.927
Publikováno v:
Nucleic Acids Research. 17:9193-9204
Three types of 14-mer oligonucleotides were hybridized to human beta-globin pre-mRNA and the resultant duplexes were tested for susceptibility to cleavage by RNase H from E. coli or from HeLa cell nuclear extract. The oligonucleotides contained norma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::856ac28de95780ff9dbf80d9d9b3ef45
https://doi.org/10.1093/nar/17.22.9193
https://doi.org/10.1093/nar/17.22.9193
Autor:
Paul J. Furdon, Sidney Altman
Publikováno v:
Nucleic acids research. 13(7)
Several addition and deletion mutations were constructed in the region of the gene for Escherichia coli tRNATyr su+3 corresponding to the dihydrouracil loop of the mature tRNA. None of these resulting mutants had detectable suppressor function compar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ca8951e1fc2f87098042e4e3c933b74
https://pubmed.ncbi.nlm.nih.gov/3889847
https://pubmed.ncbi.nlm.nih.gov/3889847
Autor:
Ryszard Kole, Paul J. Furdon
Publikováno v:
Analytical biochemistry. 162(1)
The electrophoresis step in the RNA fingerprinting procedure has been modified by replacing the large and expensive electrophoresis tank with a horizontal agarose gel electrophoresis box, a common piece of laboratory equipment. Two RNA molecules (67
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dcf63fbe7aafe28e73babd99a589535
https://pubmed.ncbi.nlm.nih.gov/2440342
https://pubmed.ncbi.nlm.nih.gov/2440342