Zobrazeno 1 - 10
of 183
pro vyhledávání: '"Paul J. Fletcher"'
Autor:
Ahmed Hasbi, Melissa L. Perreault, Maurice Y. F. Shen, Theresa Fan, Tuan Nguyen, Mohammed Alijaniaram, Tomek J. Banasikowski, Anthony A. Grace, Brian F. O'Dowd, Paul J. Fletcher, Susan R. George
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2018)
A significant subpopulation of neurons in rat nucleus accumbens (NAc) coexpress dopamine D1 and D2 receptors, which can form a D1-D2 receptor complex, but their relevance in addiction is not known. The existence of the D1-D2 heteromer in the striatum
Externí odkaz:
https://doaj.org/article/d73d0900fe7448689d960230ca5d1563
Autor:
Ishraq Siddiqui, Gary Remington, Sarah Saperia, Susana Da Silva, Paul J. Fletcher, Aristotle N. Voineskos, Konstantine K. Zakzanis, George Foussias
Publikováno v:
Schizophrenia. 8
Intrinsic motivation deficits are a prominent feature of schizophrenia that substantially impacts functional outcome. This study used cluster analysis of innate real-world behaviours captured during two open-field tasks to dimensionally examine heter
Autor:
Kerri L. Thurmon, David A. Duchene, Raphael V. Carrera, Paul J. Fletcher, J. Hogan Randall, Wilson R. Molina, Donald Neff
Publikováno v:
World Journal of Urology. 39:3587-3591
Basketing plays an important role during flexible ureteroscopy, but it can be time-consuming, especially when fragments are too large to pass through the ureteral access sheath. We aim to present the optimal on-screen, endoscopic stone size that pred
Publikováno v:
Psychopharmacology. 237:3689-3702
Environmental stimuli paired with alcohol can function as conditioned reinforcers (CRfs) and trigger relapse to alcohol-seeking. In animal models, pharmacological stressors can enhance alcohol consumption and reinstate alcohol-seeking, but it is unkn
Publikováno v:
Neuropsychopharmacology
Gambling disorder (GD) is a behavioral addiction that may be linked to alterations in dopamine (DA) systems. Gambling involves chronic exposure to uncertain reward, which can sensitize the activity of DA systems. Here we explored how combinations of
Publikováno v:
Psychopharmacology. 237:957-966
Although clozapine is effective in treating schizophrenia, it is associated with adverse side effects including weight gain and metabolic syndrome. Despite this, the role of clozapine on feeding behaviour and food intake has not been thoroughly chara
Publikováno v:
Psychopharmacology. 236:1875-1886
Adolescence is a sensitive period of brain development, during which there may be a heightened vulnerability to the effects of drug use. Despite this, the long-term effects of cannabis use during this developmental period on cognition are poorly unde
Publikováno v:
Addiction Biology. 26
The serotonin (5-HT) system has been implicated in the pathophysiology of alcohol (ethanol; EtOH) use disorders. Lorcaserin, a 5-HT2C receptor agonist, attenuates drug self-administration in animal models. We investigated the effects of lorcaserin on
Autor:
J Hogan, Randall, Raphael V, Carrera, Paul J, Fletcher, David A, Duchene, Kerri L, Thurmon, Donald A, Neff, Wilson R, Molina
Publikováno v:
World journal of urology. 39(9)
Basketing plays an important role during flexible ureteroscopy, but it can be time-consuming, especially when fragments are too large to pass through the ureteral access sheath. We aim to present the optimal on-screen, endoscopic stone size that pred
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 105
γ-aminobutyric acid (GABA)-ergic interneurons are essential for the physiological function of the mammalian central nervous system. Dysregulated GABAergic interneuron function has been implicated in the pathophysiology of a number of neurodevelopmen