Výsledky vyhledávání - "Paul J. Feeney"

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Autor: Christopher A. Lipinski, Franco Lombardo, Beryl W. Dominy, Paul J. Feeney

Publikováno v: Advanced Drug Delivery Reviews. 64:4-17

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ee4b36317c0241462ecc758365beb2b
https://doi.org/10.1016/j.addr.2012.09.019

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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 1PII of original article: S0169-409X(96)00423-1. The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 3–25. 1

Autor: Christopher A. Lipinski, Beryl W. Dominy, Paul J. Feeney, Franco Lombardo

Publikováno v: Advanced Drug Delivery Reviews. 46:3-26

Experimental and computational approaches to estimate solubility and permeability in discovery and development settings are described. In the discovery setting 'the rule of 5' predicts that poor absorption or permeation is more likely when there are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1cacaa5128417838a13b65511ed9ec29
https://doi.org/10.1016/s0169-409x(00)00129-0

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