Výsledky vyhledávání - "Paul J. Birckbichler"

The BBZDR/Wor Rat Model for Investigating the Complications of Type 2 Diabetes Mellitus

Autor: Tiangen Wu, Dennis L. Guberski, Edward H. Kislauskis, Rebecca S. Tirabassi, Joan F. Flanagan, Paul J Birckbichler

Publikováno v: ILAR Journal. 45:292-302

Congenic and inbred strains of rats offer researchers invaluable insight into the etiopathogenesis of diabetes and associated complications. The inbred Bio-Breeding Zucker diabetic rat (BBZDR)/Wor rat strain is a relatively new and emerging model of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca836c3d09fd04960bd0f42ae5586bd8
https://doi.org/10.1093/ilar.45.3.292

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Loss of tissue transglutaminase as a biomarker for prostate adenocarcinoma

Autor: Rebecca B. Bonner, Robert E. Hurst, Barbara L. Bane, Jan V. Pitha, George P. Hemstreet, Paul J Birckbichler

Publikováno v: Cancer. 89:412-423

BACKGROUND Additional molecular tissue biomarkers for prostate carcinoma are needed to stratify patients with clinically suspicious findings, such as an elevated prostate specific antigen (PSA) with a negative biopsy, according to risk. METHODS Prost

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d8d432747aab99f4560e5a155284a56a
https://doi.org/10.1002/1097-0142(20000715)89:2<412::aid-cncr29>3.0.co

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α1-Adrenergic Receptor Signaling via Gh Is Subtype Specific and Independent of Its Transglutaminase Activity

Autor: Siiri E. Iismaa, Robert M. Graham, Fang Lin, Songhai Chen, Paul J. Birckbichler, Kyung N. Lee

Publikováno v: Journal of Biological Chemistry. 271:32385-32391

Tissue transglutaminase (TGase II) is a Ca2+- and thiol-dependent enzyme that catalyzes the post-translational modification of proteins via the formation of epsilon(gamma-glutamyl) lysine bonds. We have shown previously that the GTP-binding protein,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f445462bf2cba97eaa2192dbb9779fe7
https://doi.org/10.1074/jbc.271.50.32385

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Enhanced apoptosis in transformed human lung fibroblasts after exposure to sodium butyrate

Autor: Anna Henley, Animesh Sahai, Tami C. Rowland, Graham L. Thomas, Martin Griffin, Paul J. Birckbichler

Publikováno v: In Vitro Cellular & Developmental Biology - Animal. 32:505-513

Simian virus-transformed human cells, WI-38 VA13A, showed a dose-dependent induction of apoptosis and reduction in cell numbers after exposure to sodium butyrate. Apoptosis was confirmed by ApopTag staining, isolation of apoptotic envelopes, and immu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::753d6b425e21c91e7d0fbdfbdd1dfe34
https://doi.org/10.1007/bf02723054

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