Výsledky vyhledávání - "Paul J. Barrow"

Confirmation that somatic mutations of beta-2 microglobulin correlate with a lack of recurrence in a subset of stage II mismatch repair deficient colorectal cancers from the QUASAR trial

Autor: Andrew J Wallace, David J. Kerr, Kelly Handley, Richard Gray, Phil Quirke, Laura Magill, Gordon G A Hutchins, James Hill, Paul J. Barrow, D. Gareth Evans, Susan D. Richman

Publikováno v: Histopathology
Barrow, P, Richman, S D, Wallace, A, Handley, K, Hutchins, G G A, Kerr, D, Magill, L, Evans, D G, Gray, R, Quirke, P & Hill, J 2019, ' Confirmation that somatic mutations of beta-2 microglobulin correlate with a lack of recurrence in a subset of stage II mismatch repair deficient colorectal cancers from the QUASAR trial ', Histopathology . https://doi.org/10.1111/his.13895

Aims:Beta2-Microglobulin (B2M) forms part of the HLA class I complex and plays a role in metastatic biology. B2M mutations occur frequently in mismatch repair-deficient colorectal cancer (dMMR CRC) with limited data suggesting they may protect agains

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2df909ffd82a2a5f3b3837f89d46d75c
https://eprints.whiterose.ac.uk/145822/64/Barrow_et_al-2019-Histopathology.pdf

Zobrazit plný text záznamu

Improving the uptake of predictive testing and colorectal screening in Lynch syndrome: a regional primary care survey

Autor: D. G. R. Evans, Thomas E. Clancy, James Hill, Fiona Lalloo, Kate Green, Paul J. Barrow

Publikováno v: Clinical Genetics. 87:517-524

Lynch syndrome (LS) is an autosomal dominant cancer predisposition syndrome with a 60-80% lifetime risk of colorectal cancer. We assessed the uptake of predictive testing and colorectal screening among first-degree relatives (FDRs) in LS families and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::883c19ebd200e55e9fd74b31b0db9c19
https://doi.org/10.1111/cge.12559

Zobrazit plný text záznamu

Key genetic considerations in the management of suspected hereditary colorectal cancer

Autor: D. Gareth Evans, Tara Clancy, Paul J Barrow

Publikováno v: Colorectal Cancer. 2:31-41

SUMMARY Hereditary bowel cancer syndromes account for up to 5% of colorectal cancer (CRC) incidence. Presentation of CRC under the age of 50 years should alert clinicians to a possible underlying genetic predisposition. This article focuses on Lynch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0e5be9a66ae77496225c47bb788a9d46
https://doi.org/10.2217/crc.12.75

Zobrazit plný text záznamu

Internal dressings for healing perianal abscess cavities

Autor: Katy Newton, James Hill, Lyndsay E Pearce, Zipporah Iheozor-Ejiofor, Jo C Dumville, Jennifer A Smith, Laura Hancock, Stella R Smith, Paul J. Barrow

Publikováno v: Cochrane Database Syst Rev
The Cochrane Library
Smith, S R, Newton, K, Smith, J, Dumville, J, Iheozor-Ejiofor, Z, Pearce, L, Barrow, P J, Hancock, L & Hill, J 2016, ' Internal dressings for healing perianal abscess cavities ', The Cochrane database of systematic reviews, vol. 8, CD011193 . https://doi.org/10.1002/14651858.CD011193.pub2

BACKGROUND: A perianal abscess is a collection of pus under the skin, around the anus. It usually occurs due to an infection of an anal gland. In the UK, the annual incidence is 40 per 100,000 of the adult population, and the standard treatment is ad

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faf036500e214c5b333f7d285898eea9
https://pubmed.ncbi.nlm.nih.gov/27562822

Zobrazit plný text záznamu

Timing of Laparoscopic Cholecystectomy for Acute Cholecystitis: Evidence to Support a Proposal for an Early Interval Surgery

Autor: Anas Owera, Basil J. Ammori, Paul J. Barrow, Jee K Low

Publikováno v: The American Surgeon. 73:1188-1192

We evaluated the safety and feasibility of delayed urgent laparoscopic cholecystectomy (LC) performed beyond 72 hours to overcome the logistical difficulties in performing early urgent LC within 72 hours of admission with acute cholecystitis (AC), an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::262bd9e0f8fcb5cf4eba50d73acdd51e
https://doi.org/10.1177/000313480707301123

Zobrazit plný text záznamu

Internal dressings for healing perianal abscess cavities

Autor: Stella R Smith, Lyndsay E Pearce, Katherine Newton, Jo C Dumville, Jennifer A Smith, Paul J Barrow, Laura Hancock, James Hill

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::47c51cee9092e6f8afe1138fac5be442
https://doi.org/10.1002/14651858.cd011193

Zobrazit plný text záznamu

Outcome of hepaticojejunostomy without access loop for repair of iatrogenic bile duct injury at laparoscopic cholecystectomy

Autor: Paul J. Barrow, Ajith K. Siriwardena

Publikováno v: Journal of Hepato-Biliary-Pancreatic Surgery. 14:374-376

Roux-en-Y hepaticojejunostomy is the accepted treatment for transectional biliary injury at cholecystectomy. Many authors advocate leaving a long redundant jejunal access loop to facilitate subsequent access. Reasoning that percutaneous access can be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6767314e91d930d3037ec1cf5860279
https://doi.org/10.1007/s00534-006-1174-5

Zobrazit plný text záznamu

The spectrum of urological malignancy in Lynch syndrome

Autor: D G R Evans, Fiona Lalloo, Sarah L Ingham, Kate Green, I. McIntyre, Paul J. Barrow, James Hill, Catherine O'Hara

Publikováno v: Familial cancer. 12(1)

Urological tumours are the third most frequent malignancy in Lynch syndrome after colonic and endometrial cancer. Upper urinary tract tumours are well recognised in Lynch syndrome, but the association with prostate and bladder cancer is controversial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e4c0800950441d096a5d401df0076ad
https://pubmed.ncbi.nlm.nih.gov/23054215

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání