Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Paul J Jardine"'
Autor:
Thorsten Hugel, Jens Michaelis, Craig L Hetherington, Paul J Jardine, Shelley Grimes, Jessica M Walter, Wayne Falk, Dwight L Anderson, Carlos Bustamante
Publikováno v:
PLoS Biology, Vol 5, Iss 3, p e59 (2007)
The bacteriophage phi29 generates large forces to compact its double-stranded DNA genome into a protein capsid by means of a portal motor complex. Several mechanical models for the generation of these high forces by the motor complex predict coupling
Externí odkaz:
https://doaj.org/article/c07a6fcd72fd47bdaa6c3424c0845db8
Autor:
Herman K H Fung, Shelley Grimes, Alexis Huet, Robert L Duda, Maria Chechik, Joseph Gault, Carol V Robinson, Roger W Hendrix, Paul J Jardine, James F Conway, Christoph G Baumann, Alfred A Antson
Publikováno v:
Nucleic Acids Research. 50:8719-8732
Many essential cellular processes rely on substrate rotation or translocation by a multi-subunit, ring-type NTPase. A large number of double-stranded DNA viruses, including tailed bacteriophages and herpes viruses, use a homomeric ring ATPase to proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17267723c01e98aacbd033f16eeecc1a
https://doi.org/10.1093/nar/gkac647
https://doi.org/10.1093/nar/gkac647
Autor:
Huzhang Mao, Mitul Saha, Emilio Reyes-Aldrete, Michael B. Sherman, Michael Woodson, Rockney Atz, Shelley Grimes, Paul J. Jardine, Marc C. Morais
Publikováno v:
Cell Reports, Vol 14, Iss 8, Pp 2017-2029 (2016)
Ring NTPases are a class of ubiquitous molecular motors involved in basic biological partitioning processes. dsDNA viruses encode ring ATPases that translocate their genomes to near-crystalline densities within pre-assembled viral capsids. Here, X-ra
Externí odkaz:
https://doaj.org/article/7e9b583bb87442dda5a0747b0a0936d9
Autor:
John F. Madden, Gary C. Anderson, Timothy H. Grafe, Paul J. Jardine, Siyao Shao, Qinghui Yuan, Paul S. Olin, Qisheng Ou, Rafael Grazzini Placucci, Judy Danielson, David Y.H. Pui, Jiarong Hong
Publikováno v:
The Journal of the American Dental Association. 152:981-990
Dental procedures often produce aerosols and spatter, which have the potential to transmit pathogens such as severe acute respiratory syndrome coronavirus 2. The existing literature is limited.Aerosols and spatter were generated from an ultrasonic sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f0d14fd660d760c690318bf5ae08be0
https://doi.org/10.1016/j.adaj.2021.06.007
https://doi.org/10.1016/j.adaj.2021.06.007
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Nature communications, vol 12, iss 1
Nature Communications
Nature communications, vol 12, iss 1
Nature Communications
Ring ATPases that translocate disordered polymers possess lock-washer architectures that they impose on their substrates during transport via a hand-over-hand mechanism. Here, we investigate the operation of ring motors that transport ordered, helica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60ffe6c7fe80cde287b6c485c02f4201
https://doaj.org/article/fd2702eb7c8e4254a416e2dbc6cb6580
https://doaj.org/article/fd2702eb7c8e4254a416e2dbc6cb6580
Autor:
Emilio Reyes-Aldrete, Brian A. Kelch, Erik Dill, Gaurav Arya, Joshua Pajak, Paul J. Jardine, Marc C. Morais, Mark A. White
Publikováno v:
Nucleic Acids Research
Summary Double-stranded DNA viruses package their genomes into pre-assembled protein capsids using virally-encoded ATPase ring motors. While several structures of isolated monomers (subunits) from these motors have been determined, they provide littl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::359047a8de437e93c383e97f2d9d10d4
https://doi.org/10.1093/nar/gkab372
https://doi.org/10.1093/nar/gkab372
Autor:
Feifei Wu, Changrui Lu, Fang Ding, Guangfeng Liu, Ian R. Price, Ailong Ke, Yunlong Zhang, Ting Chen, Paul J. Jardine, Rujie Cai
Publikováno v:
Nucleic Acids Research
Packaging of phage phi29 genome requires the ATPase gp16 and prohead RNA (pRNA). The highly conserved pRNA forms the interface between the connector complex and gp16. Understanding how pRNA interacts with gp16 under packaging conditions can shed ligh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ee442470f2986f30d31e373c4d89f46
http://europepmc.org/articles/PMC6765105
http://europepmc.org/articles/PMC6765105
Autor:
Mark A. White, Michael Woodson, Wei Zhang, Bryon P. Mahler, Paul J. Jardine, Gaurav Arya, Marc C. Morais, Wei Zhao, Joshua Pajak
Publikováno v:
Science Advances
A virally encoded ASCE ATPase motor ratchets between helical and planar configurations to translocate dsDNA into viral procapsids.
Molecular segregation and biopolymer manipulation require the action of molecular motors to do work by applying di
Molecular segregation and biopolymer manipulation require the action of molecular motors to do work by applying di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c18e807140587d9d40882b821ee66279
https://doi.org/10.1126/sciadv.abc1955
https://doi.org/10.1126/sciadv.abc1955
Autor:
Rockney Atz, Brian A. Kelch, Marc C. Morais, Paul J. Jardine, Joshua Pajak, Gaurav Arya, Brendan J. Hilbert
Publikováno v:
Proc Natl Acad Sci U S A
SummaryMany viruses utilize ringed packaging ATPases to translocate double-stranded DNA into procapsids during replication. A critical step in the mechanochemical cycle of such ATPases is ATP binding, which causes a subunit within the motor to grip D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57bf8707e85f2c84897062a06cb150dc
https://europepmc.org/articles/PMC8092589/
https://europepmc.org/articles/PMC8092589/
Autor:
Jiarong Hong, Paul J. Jardine, Qisheng Ou, Timothy H. Grafe, Siyao Shao, John F. Madden, David Y.H. Pui, Qinghui Yuan, Gary C. Anderson, Paul S. Olin, Judy Danielson, Rafael Grazzini Placucci
BackgroundDental procedures often produce aerosols and splatter which have the potential to transmit pathogens such as SARS-CoV-2. The existing literature is limited.MethodsAerosols and splatter were generated from an ultrasonic scaling procedure on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d401dc0e62eaa4e4aeb84ce4f61f1869
https://doi.org/10.1101/2021.02.26.21252487
https://doi.org/10.1101/2021.02.26.21252487