Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Paul J Declerck"'
Autor:
Shiraazkhan Abdul, Miet Peeters, Els Brouwers, Joyce J M C Malfliet, Frank W G Leebeek, Paul J Declerck, Dingeman C Rijken, Shirley Uitte de Willige
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0196911 (2018)
Around 70% of circulating alpha-2-antiplasmin (α2AP), the main natural plasmin inhibitor, is N-terminally cleaved between residues Pro12 and Asn13 by antiplasmin-cleaving enzyme. This converts native Met-α2AP into the more potent fibrinolysis inhib
Externí odkaz:
https://doaj.org/article/e2a6b9d1253348ceb014e9f164bf1048
Autor:
Jorrit J Hofstra, Alexander D Cornet, Paul J Declerck, Barry Dixon, Hamid Aslami, Alexander P J Vlaar, Joris J Roelofs, Tom van der Poll, Marcel Levi, Marcus J Schultz
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55262 (2013)
BACKGROUND: Critically ill patients frequently develop acute lung injury (ALI). Disturbed alveolar fibrin turnover, a characteristic feature of ALI, is the result of both activation of coagulation and inhibition of fibrinolysis. Nebulized fibrinolyti
Externí odkaz:
https://doaj.org/article/91b5a6d412d14a34965fb2314c9a9cb1
Autor:
Sebastian Seidl, Nis Valentin Nielsen, Michael Escheid, Bengt Erik Haug, Maria Stensland, Bernd Thiede, Paul J. Declerck, Geir Åge Løset, Sandip M. Kanse
Increased Factor VII activating protease (FSAP) activity has a protective effect in diverse disease conditions as inferred from studies in FSAP−/− mice and humans deficient in FSAP activity due to a single nucleotide polymorphism. The activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1bab935607a25f3e39e2a20180ce336
https://doi.org/10.1101/2022.01.09.475526
https://doi.org/10.1101/2022.01.09.475526
Autor:
Sebastian Berge-Seidl, Nis Valentin Nielsen, Armando A. Rodriguez Alfonso, Michael Etscheid, Sai Priya Sarma Kandanur, Bengt Erik Haug, Maria Stensland, Bernd Thiede, Merve Karacan, Nico Preising, Sebastian Wiese, Ludger Ständker, Paul J. Declerck, Geir Åge Løset, Sandip M. Kanse
Publikováno v:
ACS Chemical Biology
2631–2642
2631–2642
Factor VII Activating protease (FSAP) has a protective effect in diverse disease conditions as inferred from studies in FSAP-/- mice and humans deficient in FSAP activity due to single-nucleotide polymorphism. The zymogen form of FSAP in plasma is ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::575d9f37fe86a28755688db593e0dc61
https://hdl.handle.net/11250/3029761
https://hdl.handle.net/11250/3029761
Publikováno v:
Methods in enzymology. 499
Plasminogen activator inhibitor-1 (PAI-1) is the main inhibitor of tissue-type plasminogen activator (t-PA) and urokinase-type plasminogen activator (u-PA) and therefore plays an important role in the plasminogen/plasmin system. PAI-1 is involved in
Publikováno v:
Thrombosis and haemostasis. 95(5)
Autor:
Katleen, Fierens, Ann, Gils, Stefaan, Sansen, Kristof, Brijs, Christophe M, Courtin, Paul J, Declerck, Camiel J, De Ranter, Kurt, Gebruers, Anja, Rabijns, Johan, Robben, Steven, Campenhout, Guido, Volckaert, Jan A, Delcour
Publikováno v:
The FEBS journal. 272(22)
Wheat endoxylanase inhibitor TAXI-I inhibits microbial glycoside hydrolase family 11 endoxylanases. Crystallographic data of an Aspergillus niger endoxylanase-TAXI-I complex showed His374 of TAXI-I to be a key residue in endoxylanase inhibition. Its
Autor:
Ann, Gils, Paul J, Declerck
Publikováno v:
Thrombosis and haemostasis. 91(3)
Plasminogen activator inhibitor-I (PAI-I) is an important component of the plasminogen/plasmin system as it is the main inhibitor of tissue-type and urokinase-type plasminogen activator. Consequently, PAI-I plays an important role in cardiovascular d
Publikováno v:
The Journal of biological chemistry. 278(26)
The serpin plasminogen activator inhibitor-1 (PAI-1) plays an important role in the regulation of the fibrinolytic activity in blood. In plasma, PAI-1 circulates mainly in the active conformation. However, PAI-1 spontaneously converts to a latent con
Autor:
Ann, Gils, Jean-Marie, Stassen, Herbert, Nar, Joerg T, Kley, Wolfgang, Wienen, Uwe J, Ries, Paul J, Declerck
Publikováno v:
Thrombosis and haemostasis. 88(1)
Plasminogen activator inhibitor-1 (PAI-1), the primary physiological inhibitor of both tissue-type plasminogen activator and urokinase-type plasminogen activator in plasma, is a well established risk factor in thrombotic diseases. Reduction of active