Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Paul J, Silver"'
Publikováno v:
Gastro Hep Advances, Vol 3, Iss 1, Pp 48-54 (2024)
Background and Aims: Patients with health-related social needs (HRSNs) experience barriers to health care services. To identify areas of intervention, we need to understand the impact of HRSN in patients with gastroparesis. This study aimed to 1) det
Externí odkaz:
https://doaj.org/article/5e300f749e894852854b45dc48b046f3
Publikováno v:
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility SocietyREFERENCES. 34(12)
Total gastric retention (TGR) from gastric emptying scintigraphy (GES) is used for diagnosing gastroparesis (Gp), but correlates poorly with patients' symptoms. Regional intragastric meal distribution (RIMD) can also be assessed from GES. This study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21f87f67a8dcd4a8aa2a1fad6494f128
https://pubmed.ncbi.nlm.nih.gov/35929769
https://pubmed.ncbi.nlm.nih.gov/35929769
Publikováno v:
Neurogastroenterology & Motility. 34
BACKGROUND Gastric emptying scintigraphy (GES) reports percent retention at 1, 2, and 4 h. Time to empty half the meal (T½ ) could simplify GE reporting. AIMS To compare the performance of GES T½ to 1-, 2-, and 4-h retention. METHODS GES studies we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7eb6e6a07281aa1256f409232c435e84
https://doi.org/10.1111/nmo.14261
https://doi.org/10.1111/nmo.14261
Publikováno v:
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility SocietyREFERENCES. 34(5)
Gastric emptying scintigraphy (GES) reports percent retention at 1, 2, and 4 h. Time to empty half the meal (TTo compare the performance of GES TGES studies were reviewed; results determined according to retention at 1, 2, and 4 h. TOf 495 patients,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e37f1401df7949be80567ac685695db5
https://pubmed.ncbi.nlm.nih.gov/34633719
https://pubmed.ncbi.nlm.nih.gov/34633719
Publikováno v:
European Journal of Pharmacology. 400:145-153
In the current study, a glycosaminoglycan lyase, chondroitinase B, was used to study the role of dermatan sulfate proteoglycans on human dermal fibroblast proliferation. Pretreatment with chondroitinase B significantly decreased fibroblast proliferat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4354a98d702aaf9ba3ed25b54746bfd6
https://doi.org/10.1016/s0014-2999(00)00381-2
https://doi.org/10.1016/s0014-2999(00)00381-2
Publikováno v:
Journal of Cardiovascular Pharmacology. 35:29-36
Bucindolol is a nonselective β-adrenergic receptor antagonist that has additional vasodilating properties. Because some β-adrenergic receptor antagonists such as cyanopindolol are used as 5-HT 1A /5-HT 1B receptor antagonists, we tested the hypothe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a0e1e562f92925acd4351970e1a7681
https://doi.org/10.1097/00005344-200001000-00004
https://doi.org/10.1097/00005344-200001000-00004
Autor:
Paul J Silver
Publikováno v:
Expert Opinion on Investigational Drugs. 7:1003-1014
IBT 9302 (heparinase III, EC 4.2.2.8), purified from Flavobacterium heparinum, selectively cleaves heparan sulfate proteoglycans (HSPGs) from cellular surfaces and extracellular matrices. HSPGs serve as binding sites for P- and L-selectins, as well a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc22f9cfac3e763064a46b7a6f9a63ed
https://doi.org/10.1517/13543784.7.6.1003
https://doi.org/10.1517/13543784.7.6.1003
Autor:
John J. Court, Ranjit C. Desai, Dennis J. Hlasta, Paul J. Silver, E. D. Pagani, Donald C. Bode
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 7:89-94
Hybrid structural analogs 1 of the PDE V and PDE III inhibitors, zaprinast, milrinone, and CI-930 were prepared to identify dual PDE inhibitors. The SAR study led unexpectedly to the identification of WIN 61691 (8d), a potent inhibitor of PDE I (IC50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9189672dffb76fa7969fc073bb87b95a
https://doi.org/10.1016/s0960-894x(96)00578-1
https://doi.org/10.1016/s0960-894x(96)00578-1
Autor:
Donald C. Bode, Paul J. Silver, R. Allan Buchholz, Phillip F. Pratt, Keith N. Jackson, Lawrence de Garavilla, Edward D. Pagani, Marlo L. Volberg, Ronald L. Dundore
Publikováno v:
European Journal of Pharmacology. 313:89-96
Hemodynamic tolerance to nitroglycerin was developed in spontaneously hypertensive rats following 2-3 days of pretreatment with 100 mg/kg of nitroglycerin administered s.c. 3 times/day. Tolerance was evaluated both in vivo, by administering ascending
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86dca781b9b1b7332f4df017d4c534b3
https://doi.org/10.1016/0014-2999(96)00505-5
https://doi.org/10.1016/0014-2999(96)00505-5
Autor:
Robert E. Johnson, Paul J. Silver, Russell Becker, Nancy C. Birsner, Eric A. Bohnet, G. Maurice Briggs, Carl A. Busacca, Paul Canniff, Philip M. Carabateas, Thomas D'Ambra, Ronald L. Dundore, Jen-Sen Dung, Christopher C. Chadwick, Alan M. Ezrin, William Gorczyca, Peter G. Habeeb, Patrick Horan, Douglas S. Krafte, Gary Pelling, Bernard O'Connor, Manohar T. Saindane, Donald C. Schlegel, Gerald P. Stankus, John Swestock, Walter A. Volberg
Publikováno v:
Journal of Medicinal Chemistry. 38:2551-2556
A series of 4,5-dihydro-3-[2-(methanesulfonamidophenyl)ethyl]-1-phenyl- 1H-2,4-benzodiazepines has been identified as potential antiarrhythmic agents that interact at the delayed rectifier myocardial potassium channels (IKr) and prolong the ventricul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efc92eadd0db68fb0531e2763844b686
https://doi.org/10.1021/jm00014a008
https://doi.org/10.1021/jm00014a008