Zobrazeno 1 - 10
of 269
pro vyhledávání: '"Paul J, Higgins"'
Autor:
Ralf-Peter Czekay, Craig E. Higgins, Hasan Basri Aydin, Rohan Samarakoon, Nusret Bekir Subasi, Stephen P. Higgins, Hwajeong Lee, Paul J. Higgins
Publikováno v:
Cells, Vol 13, Iss 10, p 796 (2024)
A heterogenous population of inflammatory elements, other immune and nonimmune cells and cancer-associated fibroblasts (CAFs) are evident in solid malignancies where they coexist with the growing tumor mass. In highly desmoplastic malignancies, CAFs
Externí odkaz:
https://doaj.org/article/3364fa0309614b398c5065f0a181f295
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/eeaa7dd8c8484341aafd89c216c14b74
Autor:
Craig E. Higgins, Jiaqi Tang, Stephen P. Higgins, Cody C. Gifford, Badar M. Mian, David M. Jones, Wenzheng Zhang, Angelica Costello, David J. Conti, Rohan Samarakoon, Paul J. Higgins
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Tubulointerstitial fibrosis is a common and diagnostic hallmark of a spectrum of chronic renal disorders. While the etiology varies as to the causative nature of the underlying pathology, persistent TGF-β1 signaling drives the relentless progression
Externí odkaz:
https://doaj.org/article/105a7c27a3c0441384845dff57701da2
Autor:
Rohan Samarakoon, Paul J. Higgins
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/167054d374b6435f808e925f0ea0853b
Publikováno v:
Am J Physiol Renal Physiol
Mammalian kidneys consist of more than 30 different types of cells. A challenging task is to identify and characterize the stem/progenitor subpopulations that establish the lineage relationships among these cellular elements during nephrogenesis in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4178db1408b05457a5d952e68a7d3853
https://doi.org/10.1152/ajprenal.00326.2021
https://doi.org/10.1152/ajprenal.00326.2021
Supplementary Figure 4 from TGF-β1 + EGF-Initiated Invasive Potential in Transformed Human Keratinocytes Is Coupled to a Plasmin/MMP-10/MMP-1–Dependent Collagen Remodeling Axis: Role for PAI-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5722b9af4636b3dcfa661c1bf7da212f
https://doi.org/10.1158/0008-5472.22381370
https://doi.org/10.1158/0008-5472.22381370
Supplementary Figure 3 from TGF-β1 + EGF-Initiated Invasive Potential in Transformed Human Keratinocytes Is Coupled to a Plasmin/MMP-10/MMP-1–Dependent Collagen Remodeling Axis: Role for PAI-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::308bbfff8b5b3d564fb0d1d48915c22f
https://doi.org/10.1158/0008-5472.22381373
https://doi.org/10.1158/0008-5472.22381373
The phenotypic switching called epithelial-to-mesenchymal transition is frequently associated with epithelial tumor cell progression from a comparatively benign to an aggressive, invasive malignancy. Coincident with the emergence of such cellular pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cd062b83a2669eb263bb7a5464915c6
https://doi.org/10.1158/0008-5472.c.6499847.v1
https://doi.org/10.1158/0008-5472.c.6499847.v1
Supplementary Video 2C from TGF-β1 + EGF-Initiated Invasive Potential in Transformed Human Keratinocytes Is Coupled to a Plasmin/MMP-10/MMP-1–Dependent Collagen Remodeling Axis: Role for PAI-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c9c018bab52b198c59cbedbd96dd49e
https://doi.org/10.1158/0008-5472.22381364.v1
https://doi.org/10.1158/0008-5472.22381364.v1
Supplementary Figure 2 from TGF-β1 + EGF-Initiated Invasive Potential in Transformed Human Keratinocytes Is Coupled to a Plasmin/MMP-10/MMP-1–Dependent Collagen Remodeling Axis: Role for PAI-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94768d9b4fb2b3677d9380b18d342ccd
https://doi.org/10.1158/0008-5472.22381376
https://doi.org/10.1158/0008-5472.22381376