Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Paul J, Harrison"'
Autor:
Dimosthenis Tsapekos, Rebecca Strawbridge, Matteo Cella, Kimberley Goldsmith, Michail Kalfas, Rosie H. Taylor, Samuel Swidzinski, Steven Marwaha, Libby Grey, Elizabeth Newton, Julie Shackleton, Paul J. Harrison, Michael Browning, Catherine Harmer, Hannah Hartland, David Cousins, Stephen Barton, Til Wykes, Allan H. Young
Publikováno v:
BMC Psychiatry, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Background A substantial proportion of people with bipolar disorder (BD) experience persistent cognitive difficulties associated with impairments in psychosocial functioning and a poorer disorder course. Emerging evidence suggests that cogni
Externí odkaz:
https://doaj.org/article/35d105528dc743b3b5478ac94e2b9e3d
Autor:
Keisuke Inomura, Juan José Pierella Karlusich, Stephanie Dutkiewicz, Curtis Deutsch, Paul J. Harrison, Chris Bowler
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT The rapid growth of diatoms makes them one of the most pervasive and productive types of plankton in the world’s ocean, but the physiological basis for their high growth rates remains poorly understood. Here, we evaluate the factors that e
Externí odkaz:
https://doaj.org/article/e76996cf98f54f8ea43aae8336fc6968
Autor:
Gauri Ang, Laurence A. Brown, Shu K. E. Tam, Kay E. Davies, Russell G. Foster, Paul J. Harrison, Rolf Sprengel, Vladyslav V. Vyazovskiy, Peter L. Oliver, David M. Bannerman, Stuart N. Peirson
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Dysfunction of the glutamate α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor GluA1 subunit and deficits in synaptic plasticity are implicated in schizophrenia and sleep and circadian rhythm disruption. To investigate th
Externí odkaz:
https://doaj.org/article/db96924aa90f4475ae84a2e870b1ccac
Autor:
Caroline Zangani, Edoardo G Ostinelli, Katharine A Smith, James S W Hong, Orla Macdonald, Gurpreet Reen, Katherine Reid, Charles Vincent, Rebecca Syed Sheriff, Paul J Harrison, Keith Hawton, Alexandra Pitman, Rob Bale, Seena Fazel, John R Geddes, Andrea Cipriani
Publikováno v:
JMIR Mental Health, Vol 9, Iss 8, p e38600 (2022)
BackgroundThe COVID-19 pandemic required mental health services around the world to adapt quickly to the new restrictions and regulations put in place to reduce the risk of transmission. As face-to-face contact became difficult, virtual methods were
Externí odkaz:
https://doaj.org/article/a66b0f4c5b4f48d5ac783ca177647b37
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract The major anti-hypertensive (AHT) drug classes have been associated with differential risks of psychiatric disorders. However, existing data are limited largely to depression, and confounding variables have not always been controlled for. We
Externí odkaz:
https://doaj.org/article/02214146ace54ce899978c35e7b900e0
Publikováno v:
EClinicalMedicine, Vol 39, Iss , Pp 101061- (2021)
Background: There are concerns about a link between the ChAdOx1 nCoV-19 and Ad26.COV2.S vaccines against COVID-19 and cerebral venous thrombosis (CVT) and other thrombotic events. One key missing component of the risk-benefit analysis of using such v
Externí odkaz:
https://doaj.org/article/c25e96792cc54861843444dca27c7ffe
Publikováno v:
PLoS Medicine, Vol 18, Iss 9, p e1003773 (2021)
BackgroundLong-COVID refers to a variety of symptoms affecting different organs reported by people following Coronavirus Disease 2019 (COVID-19) infection. To date, there have been no robust estimates of the incidence and co-occurrence of long-COVID
Externí odkaz:
https://doaj.org/article/f5299df8a1174dd6840a98866f770fcc
Autor:
Lauren Z. Atkinson, Lucy Colbourne, Alexander Smith, Catherine H. Harmer, Anna C. Nobre, Jennifer Rendell, Helen Jones, Christopher Hinds, Arne Mould, Elizabeth M. Tunbridge, Andrea Cipriani, John R. Geddes, Kate E. A. Saunders, Paul J. Harrison
Publikováno v:
Trials, Vol 20, Iss 1, Pp 1-11 (2019)
Abstract Background The discovery that voltage-gated calcium channel genes such as CACNA1C are part of the aetiology of psychiatric disorders has rekindled interest in the therapeutic potential of L-type calcium channel (LTCC) antagonists. These drug
Externí odkaz:
https://doaj.org/article/fcd4132004e84b789465d3f37ac6ad81
Autor:
Betty Raman, Mark Philip Cassar, Elizabeth M. Tunnicliffe, Nicola Filippini, Ludovica Griffanti, Fidel Alfaro-Almagro, Thomas Okell, Fintan Sheerin, Cheng Xie, Masliza Mahmod, Ferenc E. Mózes, Adam J. Lewandowski, Eric O. Ohuma, David Holdsworth, Hanan Lamlum, Myles J. Woodman, Catherine Krasopoulos, Rebecca Mills, Flora A. Kennedy McConnell, Chaoyue Wang, Christoph Arthofer, Frederik J. Lange, Jesper Andersson, Mark Jenkinson, Charalambos Antoniades, Keith M. Channon, Mayooran Shanmuganathan, Vanessa M. Ferreira, Stefan K. Piechnik, Paul Klenerman, Christopher Brightling, Nick P. Talbot, Nayia Petousi, Najib M. Rahman, Ling-Pei Ho, Kate Saunders, John R. Geddes, Paul J. Harrison, Kyle Pattinson, Matthew J. Rowland, Brian J. Angus, Fergus Gleeson, Michael Pavlides, Ivan Koychev, Karla L. Miller, Clare Mackay, Peter Jezzard, Stephen M. Smith, Stefan Neubauer
Publikováno v:
EClinicalMedicine, Vol 31, Iss , Pp 100683- (2021)
Background: The medium-term effects of Coronavirus disease (COVID-19) on organ health, exercise capacity, cognition, quality of life and mental health are poorly understood. Methods: Fifty-eight COVID-19 patients post-hospital discharge and 30 age, s
Externí odkaz:
https://doaj.org/article/c93a8aff12744d1c8382a20c752b6745
Publikováno v:
Neurology. 100:e790-e799
Background and ObjectivesThe relationship between COVID-19 and epilepsy is uncertain. We studied the potential association between COVID-19 and seizures or epilepsy in the 6 months after infection.MethodsWe applied validated methods to an electronic