Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Paul J, Gomes"'
Publikováno v:
Ophthalmology and Therapy. 11:1449-1461
This clinical trial assessed the activity of reproxalap, a novel reactive aldehyde species modulator, and estimated clinically relevant thresholds for changes in ocular itching and redness in an allergic conjunctivitis field trial.This was a randomiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::735764087868e73cd4fd9470654ed7bf
https://doi.org/10.1007/s40123-022-00520-z
https://doi.org/10.1007/s40123-022-00520-z
Autor:
David J. Evans, Erin Reilly, Michael H Goldstein, Eugene B McLaurin, Jamie Lynne Metzinger, Fabiana Q. Silva, Paul J Gomes, Srilatha Vantipalli, Carolyn Repke, Nysha Blender, Andrea Gibson, Michelle A. Sato
Publikováno v:
American Journal of Ophthalmology. 229:288-300
PURPOSE The purpose of this study was to evaluate the efficacy and safety of a dexamethasone intracanalicular ocular insert for the treatment of allergic conjunctivitis. DESIGN Multicenter, randomized, double-masked, placebo-controlled, Phase 3 clini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e746c1f8796964145262c287521ee71
https://doi.org/10.1016/j.ajo.2021.03.017
https://doi.org/10.1016/j.ajo.2021.03.017
Autor:
Tetsuya Kawakita, Tomoko Hasunuma, David A Hollander, Paul J Gomes, Hiroshi Fujishima, Takuro Sekiya
Publikováno v:
Ocular Immunology and Inflammation. 29:1621-1626
This study evaluated the efficacy and safety of once-daily Alcaftadine 0.25% (AGN-229666) for prevention of signs and symptoms of Japanese cedar-pollen allergic conjunctivitis. This was a single-ce...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d5ef9152582c43d6931e01341299432
https://doi.org/10.1080/09273948.2020.1760309
https://doi.org/10.1080/09273948.2020.1760309
Publikováno v:
Clinical Ophthalmology. 13:403-413
Purpose The studies reported here aimed to assess the safety and tolerability of cetirizine ophthalmic solution 0.24%, a new topical ophthalmic medication approved by the US Food and Drug Administration for the treatment of ocular itching associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b78507c4b8d64a42376ce1e3fa3369fd
https://doi.org/10.2147/opth.s186092
https://doi.org/10.2147/opth.s186092
Publikováno v:
Clinical Ophthalmology (Auckland, N.Z.)
Edward J Meier,1 Gail L Torkildsen,2 Paul J Gomes,3 Mark C Jasek4 1Apex Eye, Mason, OH, USA; 2Andover Eye, Andover, MA, USA; 3Allergy, Ora, Inc., Andover, MA, USA; 4Eyevance Pharmaceuticals, TX, USA Purpose: The purpose of these Phase III studies was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba63864f025e0f91f4e0218898bde6c3
https://doi.org/10.2147/opth.s185835
https://doi.org/10.2147/opth.s185835
Publikováno v:
Ocular Immunology and Inflammation. 27:622-631
Purpose: To compare alcaftadine and olopatadine ophthalmic solutions, and vehicle for preventing allergen-mediated conjunctivitis in Japanese subjects. Methods: Japanese cedar pollen-sensitive subjects were randomized to alcaftadine 0.25%, olopatadin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::858cfbe14740ea93e8e895eab5d2b15a
https://doi.org/10.1080/09273948.2018.1432764
https://doi.org/10.1080/09273948.2018.1432764
Publikováno v:
Current Eye Research. 43:43-51
Purpose/Aims: This study assessed the efficacy and safety of brimonidine tartrate ophthalmic solution, 0.025% for treating ocular redness in adult subjects.This was a single-center, double-masked, randomized, vehicle-controlled, parallel-group study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1468359f77860b1a743d3f142183259
https://doi.org/10.1080/02713683.2017.1381269
https://doi.org/10.1080/02713683.2017.1381269
Publikováno v:
Immunity, Inflammation and Disease. 5:78-84
Introduction Field studies for allergic rhinitis (AR) commonly have inconsistent allergen concentrations and subject exposure patterns due to varying environmental conditions and subject behaviors. A technical and clinical validation study was conduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82a1e702dcf3eab3a5534a1c6a86be5a
https://doi.org/10.1002/iid3.143
https://doi.org/10.1002/iid3.143
Publikováno v:
Journal of Asthma and Allergy
Paul J Gomes,1 Keith J Lane,1 Endri Angjeli,1 Linda Stein,1 Mark B Abelson1,2 1Ora, Inc., Andover, MA, USA; 2Department of Ophthalmology, Harvard Medical School, Cambridge,MA, USA Background: Allergic rhinitis is a common condition, with ragweed poll
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1905f18b636186146d0448276a4c5914
http://europepmc.org/articles/PMC5167464
http://europepmc.org/articles/PMC5167464
Publikováno v:
Cornea
Supplemental Digital Content is Available in the Text.
Purpose: A contact lens (CL)-based drug delivery system for therapeutic delivery of the antihistamine ketotifen was tested in 2 parallel, conjunctival allergen challenge-based trials. Method
Purpose: A contact lens (CL)-based drug delivery system for therapeutic delivery of the antihistamine ketotifen was tested in 2 parallel, conjunctival allergen challenge-based trials. Method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bb9bef3df6a619f8d60247584902426
https://pubmed.ncbi.nlm.nih.gov/30908338
https://pubmed.ncbi.nlm.nih.gov/30908338