Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Paul J, Gardina"'
Autor:
Farhat Parween, Satya P. Singh, Hongwei H Zhang, Nausheen Kathuria, Francisco A. Otaizo-Carrasquero, Amirhossein Shamsaddini, Paul J. Gardina, Sundar Ganesan, Juraj Kabat, Hernan A. Lorenzi, Timothy G. Myers, Joshua M. Farber
Publikováno v:
bioRxiv
Pro-inflammatory T cells co-express multiple chemokine receptors, but the distinct functions of individual receptors on these cells are largely unknown. Human Th17 cells uniformly express the chemokine receptor CCR6, and we discovered that the subgro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a4c6a8f17e7606fe913cc5196cb4287
https://doi.org/10.1101/2023.01.25.525561
https://doi.org/10.1101/2023.01.25.525561
Autor:
Satya P. Singh, Farhat Parween, Nithin Edara, Hongwei H. Zhang, Jinguo Chen, Francisco Otaizo-Carrasquero, Debby Cheng, Nicole A. Oppenheim, Amy Ransier, Wenjun Zhu, Amirhossein Shamsaddini, Paul J. Gardina, Samuel W. Darko, Tej Pratap Singh, Daniel C. Douek, Timothy G. Myers, Joshua M. Farber
Publikováno v:
bioRxiv
Th17 cells have been investigated in mice primarily for their contributions to autoimmune diseases. However, the pathways of differentiation of Th17 and related (type 17) cells and the structure of the type 17 memory population in humans are not well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e579672a588967df5bfaa0736841126e
https://doi.org/10.1101/2023.01.05.522630
https://doi.org/10.1101/2023.01.05.522630
Autor:
Yoon-Dong Park, Joseph N. Jarvis, Guowu Hu, Sarah E. Davis, Jin Qiu, Nannan Zhang, Christopher Hollingsworth, Angela Loyse, Paul J. Gardina, Tibor Valyi-Nagy, Timothy G. Myers, Thomas S. Harrison, Tihana Bicanic, Peter R. Williamson
Publikováno v:
mBio, Vol 9, Iss 6 (2018)
ABSTRACT Human infection with Cryptococcus causes up to a quarter of a million AIDS-related deaths annually and is the most common cause of nonviral meningitis in the United States. As an opportunistic fungal pathogen, Cryptococcus neoformans is dist
Externí odkaz:
https://doaj.org/article/7eef56baff9a450683077288b9fd68cd
Autor:
Jesse H. Arbuckle, Paul J. Gardina, David N. Gordon, Heather D. Hickman, Jonathan W. Yewdell, Theodore C. Pierson, Timothy G. Myers, Thomas M. Kristie
Publikováno v:
mBio, Vol 8, Iss 4 (2017)
ABSTRACT Epigenetic regulation is based on a network of complexes that modulate the chromatin character and structure of the genome to impact gene expression, cell fate, and development. Thus, epigenetic modulators represent novel therapeutic targets
Externí odkaz:
https://doaj.org/article/6536961d25844f508d6e7f7c04d5f1cf
Autor:
Hong Duc Dang, Paul J. Gardina, Liza Lindenberg, Daniel Velez, Timothy G. Myers, David S. Schrump, Joshua M. Farber, Hongwei H. Zhang, Chang H. Paik, Xin Xu, Satya P. Singh, Tito Fojo, Jae-Ho Lee, Lyn M. Huff, Stefania Pittaluga, Ido D. Weiss, Moses O. Evbuomwan, Peter L. Choyke
Publikováno v:
Oncotarget. 8:73387-73406
// Ido D. Weiss 1 , Lyn M. Huff 2 , Moses O. Evbuomwan 3 , Xin Xu 1 , Hong Duc Dang 1 , Daniel S. Velez 1 , Satya P. Singh 1 , Hongwei H. Zhang 1 , Paul J. Gardina 4 , Jae-Ho Lee 5 , Liza Lindenberg 6 , Timothy G. Myers 4 , Chang H. Paik 5 , David S.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e370968c89721a2c15964a165e18d0f
https://doi.org/10.18632/oncotarget.19945
https://doi.org/10.18632/oncotarget.19945
Publikováno v:
Tuberculosis. 120:101895
New vaccines are needed to combat the public health threat posed by M. tuberculosis (M. tb), but no correlates have been defined to aid vaccine development. Using mouse models, we previously developed an in vitro system that measures the ability of M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99e0ff63cbc43540c83ee870cc62b043
https://doi.org/10.1016/j.tube.2019.101895
https://doi.org/10.1016/j.tube.2019.101895
Autor:
Timothy G. Myers, Angela Loyse, Joseph N Jarvis, Peter R. Williamson, Sarah E. Davis, Thomas S. Harrison, Guowu Hu, Nannan Zhang, Yoon-Dong Park, Tibor Valyi-Nagy, Christopher Hollingsworth, Paul J. Gardina, Jin Qiu, Tihana Bicanic
Publikováno v:
mBio
mBio, Vol 9, Iss 6, p e02353-18 (2018)
mBio, Vol 9, Iss 6 (2018)
mBio, Vol 9, Iss 6, p e02353-18 (2018)
mBio, Vol 9, Iss 6 (2018)
Cryptococcus is a fungal pathogen that kills an estimated quarter of a million individuals yearly and is the most common cause of nonviral meningitis in the United States. The fungus is carried in about 10% of the adult population and, after reactiva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::939c7861ede7079349a38fba6d95e29d
http://europepmc.org/articles/PMC6299223
http://europepmc.org/articles/PMC6299223
Autor:
Ido D, Weiss, Lyn M, Huff, Moses O, Evbuomwan, Xin, Xu, Hong Duc, Dang, Daniel S, Velez, Satya P, Singh, Hongwei H, Zhang, Paul J, Gardina, Jae-Ho, Lee, Liza, Lindenberg, Timothy G, Myers, Chang H, Paik, David S, Schrump, Stefania, Pittaluga, Peter L, Choyke, Tito, Fojo, Joshua M, Farber
Publikováno v:
Oncotarget
Expression of the chemokine receptor CXCR4 by many cancers correlates with aggressive clinical behavior. As part of the initial studies in a project whose goal was to quantify CXCR4 expression on cancers non-invasively, we examined CXCR4 expression i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::55975096280d9f8c2cb343fdd8bd5411
https://pubmed.ncbi.nlm.nih.gov/29088715
https://pubmed.ncbi.nlm.nih.gov/29088715
Autor:
Catherine Riou, Ian N. Moore, Paul J. Gardina, Alan Sher, Timothy G. Myers, Elsa Du Bruyn, Keith D. Kauffman, Taylor W. Foreman, Daniel L. Barber, Shunsuke Sakai, Temeri Wilder-Kofie, Cecilia S. Lindestam Arlehamn, Stella G. Hoft, Alessandro Sette, Robert J. Wilkinson, Michelle A. Sallin, Rashida Moore
Publikováno v:
Nature microbiology. 3(11)
Mycobacterium tuberculosis infection (Mtb) is the leading cause of death due to a single infectious agent and is among the top ten causes of all human deaths worldwide1. CD4 T cells are essential for resistance to Mtb infection, and for decades it ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8375cea3bac80de13e2b8d6d0375f85f
https://pubmed.ncbi.nlm.nih.gov/30356152
https://pubmed.ncbi.nlm.nih.gov/30356152
Autor:
Paul J. Gardina, Timothy G. Myers, Joshua M. Farber, Hongwei H. Zhang, Satya P. Singh, Chang Hoon Lee, Vijayaraj Nagarajan, Hsinyi Tsang
Publikováno v:
The Journal of Immunology. 194:4350-4361
Th17 cells, which express the chemokine receptor CCR6, are implicated in many immune-mediated disorders, such as psoriasis and multiple sclerosis. We found that expression levels of CCR6 on human effector/memory CD4+ T cells reflect a continuum of Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d94a10505a78442bf63fd828dc7862d3
https://doi.org/10.4049/jimmunol.1401093
https://doi.org/10.4049/jimmunol.1401093