Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Paul Heo"'
Autor:
Laurence Lecordier, Paul Heo, Jonas H. Graversen, Dorle Hennig, Maria Kløjgaard Skytthe, Alexandre Cornet d’Elzius, Frédéric Pincet, David Pérez-Morga, Etienne Pays
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113528- (2023)
Summary: Apolipoproteins L1 and L3 (APOLs) are associated at the Golgi with the membrane fission factors phosphatidylinositol 4-kinase-IIIB (PI4KB) and non-muscular myosin 2A. Either APOL1 C-terminal truncation (APOL1Δ) or APOL3 deletion (APOL3-KO [
Externí odkaz:
https://doaj.org/article/f14274957a20483d908e98fc48560d83
Publikováno v:
FEBS Open Bio, Vol 12, Iss 11, Pp 1958-1979 (2022)
Membrane fusion is not a spontaneous process. Physiologically, the formation of coiled‐coil protein complexes, the SNAREpins, bridges the membrane of a vesicle and a target membrane, brings them in close contact, and provides the energy necessary f
Externí odkaz:
https://doaj.org/article/0accfd61d7fc437dbf4fc7067f10d0a9
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111921- (2023)
Summary: Tail-anchored (TA) proteins contain a single C-terminal transmembrane domain (TMD) that is captured by the cytosolic Get3 in yeast (TRC40 in humans). Get3 delivers TA proteins to the Get1/2 complex for insertion into the endoplasmic reticulu
Externí odkaz:
https://doaj.org/article/3140225396d546c5a27daedc9d467434
Autor:
Byoungjae Kong, Seokoh Moon, Yuna Kim, Paul Heo, Younghun Jung, Seok-Hyeon Yu, Jinhyo Chung, Choongjin Ban, Yong Ho Kim, Paul Kim, Beom Jeung Hwang, Woo-Jae Chung, Yeon-Kyun Shin, Baik Lin Seong, Dae-Hyuk Kweon
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Membrane-disrupting agents that selectively target virus versus host membranes could potentially be potent antivirals. Here the authors incorporate a decoy virus receptor into a nanodisc and show that it ruptures the viral membrane at low pH and trap
Externí odkaz:
https://doaj.org/article/3dd9feb19abe4cd5836438ceb64097b5
Autor:
Paul Heo, Frederic Pincet
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-8 (2020)
Communications Biology
Communications Biology, Nature Publishing Group, 2020, 3 (1), ⟨10.1038/s42003-020-0883-7⟩
Communications Biology
Communications Biology, Nature Publishing Group, 2020, 3 (1), ⟨10.1038/s42003-020-0883-7⟩
Synucleinopathies are neurological diseases that are characterized by the accumulation of aggregates of a cytosolic protein, α-synuclein, at the plasma membrane. Even though the pathological role of the protein is established, the mechanism by which
Autor:
Dae-Hyuk Kweon, Younghun Jung, Byoungjae Kong, Jonghyeok Shin, Myungseo Park, Paul Heo, Joon-Bum Park
Publikováno v:
Biochemical and Biophysical Research Communications. 488:53-59
Soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins mediate intracellular membrane fusion by forming a ternary SNARE complex. A minimalist approach utilizing proteoliposomes with reconstituted SNARE proteins yielded
Autor:
Sathish Ramakrishnan, Paul Heo, Frederic Pincet, Jean-Baptiste Fleury, Jeff Coleman, James E. Rothman
Publikováno v:
Small
Small, Wiley-VCH Verlag, 2019, 15 (21), pp.1900725. ⟨10.1002/smll.201900725⟩
Small, Wiley-VCH Verlag, 2019, 15 (21), pp.1900725. ⟨10.1002/smll.201900725⟩
Experimental setups to produce and to monitor model membranes have been successfully used for decades and brought invaluable insights into many areas of biology. However, they all have limitations that prevent the full in vitro mimicking and monitori
Autor:
Pan-Jun Kim, Da Hyeong Cho, Dae-Hee Lee, Jun Seob Kim, Choong Hwan Lee, Jaeyun Sung, Paul Heo, Dongwoo Shin, Suk Chae Jung, Myungseo Park, Eun Joong Oh, Dae-Hyuk Kweon, Suk Chan Lee, Sarah Lee, Yong Su Jin
Publikováno v:
Antimicrobial Agents and Chemotherapy. 60:2232-2240
Bacterial persisters are a small fraction of quiescent cells that survive in the presence of lethal concentrations of antibiotics. They can regrow to give rise to a new population that has the same vulnerability to the antibiotics as did the parental
Autor:
Dae-Hyuk Kweon, Jun-Bum Park, Byoungjae Kong, Jonghyeok Shin, Yoosoo Yang, Paul Heo, Younghun Jung, Cherlhyun Jeong
Publikováno v:
Biochemical and Biophysical Research Communications. 465:864-870
Soluble N-ethylmaleimide-sensitive-factor attachment protein receptor (SNARE) proteins generate energy required for membrane fusion. They form a parallelly aligned four-helix bundle called the SNARE complex, whose formation is initiated from the N te
Publikováno v:
The FASEB Journal. 34:1-1