Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Paul Hellewell"'
Autor:
Ingrid Gomez, Ben Ward, Celine Souilhol, Chiara Recarti, Mark Ariaans, Jessica Johnston, Amanda Burnett, Marwa Mahmoud, Le Anh Luong, Laura West, Merete Long, Sion Parry, Rachel Woods, Carl Hulston, Birke Benedikter, Chiara Niespolo, Rohit Bazaz, Sheila Francis, Endre Kiss-Toth, Marc van Zandvoort, Andreas Schober, Paul Hellewell, Paul C. Evans, Victoria Ridger
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
The role of neutrophils in the development of atherosclerosis has long been an enigma, with few neutrophils detected within the plaque. Here, the authors show that microvesicles released from neutrophils increase vascular inflammation and enhance ath
Externí odkaz:
https://doaj.org/article/56d869ba2dc54e5c8b181fd48b5df87b
Autor:
Amanda Burnett, Ingrid Gomez, David Davila De Leon, Mark Ariaans, Pavlos Progias, Richard A. Kammerer, Guillermo Velasco, Marie Marron, Paul Hellewell, Victoria Ridger
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Angiopoietins are a family of growth factors that are ligands for the tyrosine kinase receptor, Tie2. Angiopoietin 1 (Ang-1) is agonistic for Tie2, plays a key role in blood vessel maturation and stability and has been shown to possess anti-
Externí odkaz:
https://doaj.org/article/13276e96cb424136925e3edbd894f7ad
Autor:
Chiara Recarti, Le Anh Luong, Amanda Burnett, Celine Souilhol, Ben Ward, Endre Kiss-Toth, Jessica Johnston, Victoria Ridger, Merete Long, Marwa Mahmoud, Sheila E. Francis, Andreas Schober, Siôn A Parry, Paul Hellewell, Marc A. M. J. van Zandvoort, Mark P. Ariaans, Carl J. Hulston, Birke J. Benedikter, Ingrid Gomez, Rachel M Woods, Laura West, Paul C. Evans, Rohit Bazaz
Neutrophils have been implicated in the pathogenesis of atherosclerosis, a lipid-driven disease of arteries, but they are seldom found in atherosclerotic plaques. To resolve this longstanding paradox, we investigated whether neutrophil-derived microv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::809f542794cdfee829847af7dcd9abb4
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 35
Background: Atherosclerosis is the most common underlying cause of cardiovascular disease. Many cells types are involved in the initiation and progression of atherosclerotic plaques but, until recently, neutrophils were not considered to be among the
Publikováno v:
Heart. 101:A122-A123
Background Many cell types are involved in the initiation and progression of atherosclerosis but neutrophils are rarely considered to be among them. However, despite their infrequent detection in plaques, neutrophils have been shown to facilitate the