Zobrazeno 1 - 10
of 267
pro vyhledávání: '"Paul Heinrich"'
Autor:
Laura Joachim, Sascha Göttert, Anna Sax, Katja Steiger, Klaus Neuhaus, Paul Heinrich, Kaiji Fan, Erik Thiele Orberg, Karin Kleigrewe, Jürgen Ruland, Florian Bassermann, Wolfgang Herr, Christian Posch, Simon Heidegger, Hendrik Poeck
Publikováno v:
EBioMedicine, Vol 97, Iss , Pp 104834- (2023)
Summary: Background: Inter-individual differences in response to immune checkpoint inhibitors (ICI) remain a major challenge in cancer treatment. The composition of the gut microbiome has been associated with differential ICI outcome, but the underly
Externí odkaz:
https://doaj.org/article/12cd81f05fce4a928aea82b9ae65b9a3
Autor:
Harald Lahm, Paul Heinrich, Elisabeth Zierler, Elda Dzilic, Irina Neb, Tatjana Luzius, Stefanie A. Doppler, Stephanie Schneider, Rüdiger Lange, Markus Krane, Martina Dreßen
Publikováno v:
Stem Cell Research, Vol 60, Iss , Pp 102691- (2022)
A number of mutations in the human TBX5 gene have been described which cause Holt-Oram syndrome, a severe congenital disease associated with abnormalities in heart and upper limb development. We have used a prime-editing approach to introduce a patie
Externí odkaz:
https://doaj.org/article/3834585b3c9b43dfa1ba102c48872f67
Publikováno v:
Journal of Pediatric Surgery Case Reports, Vol 64, Iss , Pp 101695- (2021)
Introduction: Stoma closure surgery (SCS; restoring intestinal continuity) in children is associated with high post-surgical complication rates with no established preventive strategies. Although many of these complications can be directly or indirec
Externí odkaz:
https://doaj.org/article/c62cb8b4bbe642ec9469d460d5590202
Autor:
Maren Feist, Philipp Schwarzfischer, Paul Heinrich, Xueni Sun, Judith Kemper, Frederike von Bonin, Paula Perez-Rubio, Franziska Taruttis, Thorsten Rehberg, Katja Dettmer, Wolfram Gronwald, Jörg Reinders, Julia C. Engelmann, Jan Dudek, Wolfram Klapper, Lorenz Trümper, Rainer Spang, Peter J. Oefner, Dieter Kube
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Metabolic rewiring of cancer cells can be driven by both extrinsic and intrinsic factors. Here the authors show that microenvironmental factors induce metabolic rewiring of B-cell lymphoma through activation of STAT3 and NF-ΚB resulting in upregulat
Externí odkaz:
https://doaj.org/article/10dedebdb6144adc9af992f5ae10844d
Autor:
Xueni Sun, Raffaela S. Berger, Paul Heinrich, Ibtissam Marchiq, Jacques Pouyssegur, Kathrin Renner, Peter J. Oefner, Katja Dettmer
Publikováno v:
Metabolites, Vol 10, Iss 7, p 292 (2020)
Glutathione (GSH) and glutathione disulfide (GSSG) are commonly used to assess the oxidative status of a biological system. Various protocols are available for the analysis of GSH and GSSG in biomedical specimens. In this study, we present an optimiz
Externí odkaz:
https://doaj.org/article/cfc6ad44c7b643f5b9e35fc2d6f0f423
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